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    Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination
    Sanger sequencing is commonly taught with a hands-on approach. Sanger sequencing involves chain termination by dideoxynucleotides, because they are missing the oxygen on the 3’ carbon atom,...

    Keywords: nucleotidessequencingDNAgel electrophoresisChain Termination

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    Module 2: Transcription Part I: From DNA Sequence to Transcription Unit
    This module illustrates how a primary transcript (pre-mRNA) is synthesized using a DNA molecule as the template. Students will learn about the importance of the 5' and 3' regions of the gene for...

    Keywords: data visualizationmolecular biologybioinformaticsGenome BrowsergenomicsTranscription InitiationTranscription Start SiteTranscription Termination Signal

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    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

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    Food Chain Dynamics In A Simple Ecosystem
    In this lab, students will work with a simple algae/brine shrimp environment to learn about food chains and population dynamics.

    Keywords: ecologyecosystemsfood chainalgae

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    Food Chain Dynamics In A Simple Ecosystem
    In this lab, students will work with a simple algae/brine shrimp environment to learn about food chains and population dynamics. It was implemented with limited alteration for an Introductory...

    Keywords: ecologyecosystemsfood chain

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    Food Chain Dynamics In A Simple Ecosystem
    In this lab, students will work with a simple algae/brine shrimp environment to learn about food chains and population dynamics.

    Keywords: ecologyecosystemsfood chain

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    2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
    The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important...

    Keywords: paracetamolpharmacokineticsstomachsmall intestinesulfapyridine

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    Malawian Aquaculture Pond Ecosystem Challenge
    This case study challenges students to design a pond that will provide supplemental food security to a rural Malawian village. In the process they apply concepts of primary and secondary...
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    Half Life of mRNA
    This module introduces exponential growth and decay in the context of understanding the stability of mRNA. It is intended for an introductory biology audience.

    Keywords: exponential equationsGenetic Informationlogarithmic equationshalf-lifemRNA

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    Food Chain Dynamics In A Simple Ecosystem
    In this lab, students will construct simple experiments with algae and brine shrimp to learn about food chains and population dynamics.

    Keywords: ecologyecosystemsfood chainalgaebrine shrimp

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    Predicting and classifying effects of insertion and deletion mutations on protein coding regions
    Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of...

    Keywords: mutationcentral dogmatranslationframeshift

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    Learn genomics and bioinformatics through scientific thinking, creation and analysis (virtual and hands-on)
    Nucleic acid are biological molecules composed of nitrogen-containing bases, phosphate groups, and sugar molecules. The complimentary chemical bonding results in formation of double stranded DNA....

    Keywords: data analysisbioinformaticsnucleotidesproteinsRNAgenomicsScientific communicationscientific writingDNAmodelling scientific thinkinggenescientific thinkingcreation

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    A rainforest with a gold chain? The impacts of gold mining on the trophic web of an Amazonian rainforest of SE Peru
    The use of mercury in artisanal gold mining affects aquatic and terrestrial food webs in the Peruvian Amazon. Learn about bioaccumulation, explore data on mercury deposition in vegetation and how...

    Keywords: conservation biologydeforestationhuman healthpollutionbiodiversity losstropical land use

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    Modeling Trophic Interactions in Rice Agriculture: A Jigsaw Approach
    Students explore four different issues related to trophic interactions that affect modern rice agriculture practices and consider relationships between these issues using Lotka and Volterra...

    Keywords: mathematical modelLotka-Volterrajigsawfood chaintrophic cascadespredator-prey interactionsfood web

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    Understanding Trophic Interactions in Rice Agriculture: A Jigsaw Approach
    Students explore four different issues related to trophic interactions that affect modern rice agriculture practices and consider relationships between these issues.

    Keywords: jigsawfood chaintrophic cascadesfood web

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    Population dynamics in simple two-species experimental microcosms
    A two-week exercise which includes homework calculations and teaching resources. Students establish brine shrimp and Platymonas algal cultures and predict final densities.

    Keywords: population dynamicsecologyspecies interactionsbotanyecosystemsfood chainpopulation regulation

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    Implementing an online module about the implications of gold mining in the Amazonian rainforest for a community college ecology course
    This online module describes the implications of gold mining in the Amazon Rainforest, introduces students to ecological concepts, and explores human-environment connections. The implementation...
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    BSL-4: Authorized Personnel Only
    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    Keywords: infectious diseaseexperimental designbioinformaticsEbolaNIBLSECase It!PCRBLASTmultiple sequence alignmentPublished in National Center for Case Study Teaching in Sciencepolymerase chain reactionfebrile illnessvirusELISAenzyme linked immunosorbent assayfilovirusAfrica

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    A simple way for students to visualize cellular respiration: adapting the board game MousetrapTM to model complexity
    Lecture-based introductory biology courses are typically content-heavy as instructors strive to provide students with foundational knowledge in a broad range of topics.  One topic...

    Keywords: ATPGlycolysisCellular RespirationElectron Transport ChainKrebs Cycle

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    Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis
    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education,...

    Keywords: transcriptioncentral dogmatranslationsequence analysisDNA replicationgenetic variants

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