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    Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics
    Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of...

    Keywords: cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

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    A Phylogenetic Analysis of the Evolution of the CRYAA Gene Across Vertebrates
    Although the divergence of the aA-crystallin protein from other heat shock proteins has been examined, the extent to which the CRYAA gene controlling it has evolved across vertebrate species...

    Keywords: phylogeneticsvertebrates

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    BSL-4: Authorized Personnel Only
    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    Keywords: infectious diseaseexperimental designbioinformaticsEbolaNIBLSECase It!PCRBLASTmultiple sequence alignmentPublished in National Center for Case Study Teaching in Sciencepolymerase chain reactionfebrile illnessvirusELISAenzyme linked immunosorbent assayfilovirusAfrica

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    Build Multiomic and Visualization Skills in Bioscience Lecture
    This resource promotes inclusive learning by using all free platforms to extend the central dogma to an applied experience. Genomics is focused on with literature reviews that are performed to...

    Keywords: geneticsBiochemistryBiology and Biochemistry EduationProtein StructureBioinformatics and GenomicsFunctional GenomicstranscriptomicsproteomicsRNAseqClinical genomicsprotein structure modelingInclusive teaching3D protein structure /function analysisinclusive classrooms3D protein structuresinclusivegene

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    Using Bioinformatics Activities to understand the Past and Present of SARS-CoV2
    We have designed a Bioinformatics activity that uses tools to identify the origins and mutations in the novel SARS-CoV2 strains.
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    A Critical Guide to BLAST
    This Critical Guide in the Introduction to Bioinformatics series provides an overview of the BLAST similarity search tool, briefly examining the underlying algorithm and its rise to popularity.

    Keywords: NIBLSEBLASTGOBLETInstructorResources

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    When did I lose my legs? A limbless lizard tale
    Using oVERT project models students examine examples of extant traditional lizards, snakes and limbless lizards and create phylogenies based on trait and genetic data.

    Keywords: phylogeneticsevolutionary biologyHerpetologynatural history collections3D models#NGSSdigitized natural history collectionsoVertConvergent Evolution

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    GEA Introductory lesson on RNA-Seq
    This RNA-Seq lesson uses the CyVerse VICE Platform and Jupyter notebooks to examine the expression of the leptin gene in samples from a mouse experimental design evaluating diet (high-fat vs....

    Keywords: data sciencebioinformaticsGenome BrowserRNAseqhigh throughput sequencingmRNAAlignmentNCBI Sequence Read Archive

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    A Fun Introductory Command Line Exercise: Next Generation Sequencing Quality Analysis with Emoji!
    This resource is a fun computer-based intro to command line programming. The activity takes FASTQ NGS data files and runs a fun program called FASTQE.

    Keywords: data sciencebioinformaticsnext generation sequencingquality controlFASTQgenomicsprogrammingNIBLSElinuxmicrobiomeIllumina sequencingcommand lineFASTQEFASTPNGS analysisterminalMacemojiPhred scoreTrimmingshort read

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    The Effect of Climate Change on Butterfly Phenology - Intro Environmental Science
    In this module, students practice interpreting the relationship between variables before exploring changes in butterfly phenology through the use of natural history collections data.

    Keywords: ExcelResources @ ESA - TIEEgraphingquantitative literacyclimate changefmnphenologynatural history collectionsDIGbutterflyinterspecific interactions

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    Citations
    Published Avida-Ed article

    Keywords: EvolutioncurriculumSelectionDigital Organisms

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    2020-Stepien_Kostelich_Kuang-Mathematics Cancer An Undergraduate Bridge Course in Applied Mathematics
    Most undergraduates have limited experience with mathematical modeling. This paper describes a course on the mathematical models of cancer growth and treatment.

    Keywords: differential equationsmodelingundergraduate educationcancertumor

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    Introduction to nucleotide sequence analysis and protein modeling in MEGA and PyMol using coronavirus SARS-CoV-2
    Introduction into computational approaches in phylogeny and protein modeling based on coronavirus SARS-CoV-2 (caused COVID-19 pandemic). Two self-guided tutorials for standard lab classes of 2.5...

    Keywords: phylogeneticsundergraduate educationbioinformaticsNCBICOVID19coronavirusMEGAPyMolvirtual labPDBprotein modelingSARSSARS-CoV

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    Introduction to Phylogenetic Trees for Comparative Genomic Analysis
    In this activity, students are introduced to phylogenetic trees and networks as tools for analyzing evolutionary relationships.
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    Data Analysis Recitation Activities Support Better Understanding in SEA-PHAGES CURE
    Course-based undergraduate research experiences (CUREs) are widely known to improve student learning outcomes in the sciences. Undergraduate students have a particularly difficult time interpreting...

    Keywords: bacteriophageDNA extractionGel analysisPhage purificationTiter calculationViral replicative growth

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    HITS: A network to create inquiry-based case studies that make high-throughput approaches and discovery accessible
    Poster on the work of the NSF-funded High-throughput Discovery Science & Inquiry-based Case Studies for Today’s Students (HITS) Research Coordination Network. Presented at the 2021 BIOME Institute.

    Keywords: case studieshigh-throughputHITSHigh-throughput Discovery Science & Inquiry-based Case Studies for Today’s Students2021 BIOME

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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisgenetic basisPDBMolecular Case StudyMol*

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    Sex-specific differences in Meiosis: Real-world applications
    In traditional classrooms, students are typically presented with facts that they are asked to memorize and recall during an exam.  The rapid explosion of available scientific facts in recent...

    Keywords: meiosisReproductionAneuploidyGameteNon-disjunctionOocyteSpermTrisomy

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    From Cre/LoxP to Fate Maps: Inclusive and Equitable Approaches for Engaging Developmental Biology Students in Experimental Design
    Engaging first generation underrepresented minority students in the process of inquiry in developmental biology is important to increase diversity in future graduate STEM education. One important...

    Keywords: experimental designC. elegansCre/LoxPFate mapheart developmentheart regenerationmousereporter constructzebrafish

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    Snapshot Serengeti: Implementing an online module about Serengeti wildlife ecology in a community-college ecology course
    This resource describes the implementation plan for an undergraduate ecology course at Muscatine Community College, Iowa, of an online module featuring a database on Serengeti wildlife populations....

    Keywords: ecologywildlifewildlife managementWildlife ecology

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