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    Sequence Similarity in Developmental Biology - A Bioinformatics Exercise Using Myostatin
    This exercise leads upper level biology majors in an inquiry-based excursion to determine how similar the signaling molecule, myostatin, is between humans and mice, using a basic set of...
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    Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans
    Incorporating authentic research experiences into undergraduate labs, while shown to be particularly effective at engaging and retaining students in STEM majors, can be difficult to accomplish...

    Keywords: gene regulationmicroRNAsgene expression

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    2000-Idels-Wang-Harvesting Fisheries Management Strategies With Modified Effort Function
    This study concludes that a control parameter beta (the magnitude of the effect of the fish population size on the fishing effort function E), changes not only the rate at which the population goes...

    Keywords: sustainabilityfishFishingmanagementharvestfisherstrategyoverfishing

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    6-005-InsectColonySurvivalOpt-ModelingScenario
    We present a system of nonlinear differential equations to model the control of energy flow into producing workers or reproducers in an insect colony, using a set of given parameters and a number...

    Keywords: optimizationOptimal Control Theoryinsect colonyoptimal controlnatural resourcesPointryagin's Maximum Principlecontrol variable

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    2008-Ratneesh_Suri-Optimal harvesting strategies for fisheries-differential equations approach
    We develop and investigate the harvesting model in both deterministic and stochastic settings. We first employ the Expected Net Present Value approach and determine optimal harvesting policy using...

    Keywords: optimal controlsustainable yieldmaximum sustainable yieldharvestExpected Net Present Valuecalculus of variationsdynamic programmingmaximum economic yield

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    Using Musical Instruments to Model Negative Feedback in the Hypothalamo-Pituitary-Target Gland Axes
    Homeostasis and negative feedback are crucial, yet difficult, concepts for undergraduates, particularly in the context of the hypothalamo-pituitary axes. This interactive activity was designed to...

    Keywords: cell-cell communicationhomeostasisnegative feedback

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    1-104A-T-InfectionRisk-ModelingScenario
    This project is designed to examine differences between the exponential and logistic growth models in biology and how to apply these models in solving epidemic questions and comparing to actual...

    Keywords: regressioninfectionCOVID19carrying capacitylogistic equationexponential model

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    2016-Wilkie-EtAl-Using ODEs to Explore Cancer-Immune Dynamics and Tumor Dormancy
    Here we present a general method using ordinary differential equations (ODEs) to model and analyze cancer-immune interactions, and in particular, immune-induced tumor dormancy.

    Keywords: cancertumor-inhibiting cytotoxic actiontumor-promoting inflammationimmune-induced tumor dormancytumor growth dynamics

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    2019-Fred_Brauer-The_Final_Size_of_a_Serious_Epidemic
    In an epidemic of a serious disease, there is likely to be behavioral response that decreases the epidemic size considerably.

    Keywords: epidemicfinal sizebehavioral responseSIER modelrelations

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    Studying disease with Dr. Ameeta Parekh of the FDA
    Ameeta Parekh, Ph.D. is the Senior Advisor for Scientific Collaborations in the Office of Translational Sciences for the FDA. She talked to us about the FDA's mission and purpose, an overview of...

    Keywords: diseasedrugsregulatory complianceFDA

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    Machine Learning Meets Medicine with Jenessa Peterson
    Jenessa Peterson is a former teacher turned data scientist/engineer and Director of Learning Engineering at The Learning Agency. Her more recent work in data science has included building a...

    Keywords: data sciencemachine learningmedicine

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    6-010-SocialCampaign-ModelingScenario
    The epidemic modeling problem is formulated as a system of three nonlinear, first order differential equations in which three compartments (S, I, and R) of the population are linked.

    Keywords: diseasegrowth rateJudgment and Decision MakingSIR modelinfections diseasesocial campaignrecovery ratedelay timejoining processquitting processexponential distribution

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    6-016-PandemicModeling-ModelingScenario
    The recent coronavirus outbreak has infected millions of people worldwide and spread to over 200 countries. How can we use differential equations to study the spread of coronavirus?

    Keywords: population dynamicsinfectious diseasediseaseEbolaeSIR modelsCOVID19pandemicepidemicreproduction number

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    The Human Microbiome Biodiversity in Health and Disease
    The students will analyze the human gut and vaginal microbiomes in healthy and diseased states using diversity of bacteria as determined by 16SrRNA sequence.
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    Cancer Discovery Activities
    These two hands-on activities are based on a Howard Hughes Medical Institute 2013 Holiday Lectures on Science video (http://www.hhmi.org/biointeractive/cancer-genetic-disease-video-highlights)...

    Keywords: geneticsResources @ HHMI - BioInteractiveorganismal biologyneurosciencegenomicscancergenetic basis of diseasebiology of cellsHigh School

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    Disease Spread Simulation with M&M's and Information on the wider SIMIODE community
    This is a Student Version of a Modeling Scenario from the community, SIMIODE - Systemic Initiative for Modeling Investigations and Opportunities with Differential Equations at www.simiode.org

    Keywords: resourcesdifferential equationsmodelingsimulationmoduledataepidemicsdiseasecommunityapplied mathematicsResources @ SIMIODEretinal surgeryinsect colonyLSDm&mparameter estimationin-class activityproject

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    2017-Jean-Roux-Mathematical Models in Air Quality Problems
    Presents many models with analysis in air quality control. Starts with chemical kinetics models and builds complexity to PDE models.

    Keywords: air pollution effects on forest ecosystemsfinite volume methodboundary layerchemical kineticsfinite differenceemissionsdepositionsadvection

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    2005-DieboldEtAl-Modeling Bond Yields In Finance And Macroeconomics
    From a macroeconomic perspective, the short-term interest rate is a policy instrument under the direct control of the central bank. From a finance perspective, long rates are risk-adjusted averages...

    Keywords: financeinterest ratebond yieldmacroeconomics

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    1994-S_S_Everingham-C_Peter_Rydell-Modeling the Demand for Cocaine
    This is a report prepared for the Office of National Drug Control Policy of the United States Army by the Rand Corporation. The report contains lots of data and builds a two compartment difference...

    Keywords: drugstwo compartmentcocainedemand

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    Factor Structure Assessment of the Students Support Needs Scale-Augmented for African-American STEM Students
    Poster on the impact of a performance pyramid-based peer-led learning community on course knowledge at a Historically Black University. Presented at the 2021 BIOME Institute.

    Keywords: modelingSTEM education2021 BIOMEfactor structure

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