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    Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway
    Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions.  This...

    Keywords: SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur

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    Learning About Protein Localization: A Lesson for Analyzing Figures in a Scientific Publication
    In order to function correctly, proteins must be localized to a specific subcellular location. We have designed this lesson to use data from the primary literature to teach students about the...

    Keywords: colocalizationimmunofluorescenceProtein localizationsignal sequencessubcellular fractionationwestern blotting

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    Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course
    A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it...

    Keywords: structure-functionEnzymeallosteric regulationcompetitive inhibitionfeedback inhibitionnoncompetitive inhibitionproductsubstrate

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    Drawing flowcharts of lab protocols helps students prepare for biology labs
    With the publishing of the Vision and Change report, we know it is best practice to include authentic research experiences in our undergraduate science lab classes. One big challenge in teaching...

    Keywords: laboratorymolecular biologyUndergraduateprotocolflowchart

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    Fly Exercise: A Simple Experiment to Test the Physiological Effects of Exercise on a Model Organism
    Model organisms are commonly used to study and experimentally explore biological processes in ways that are technically or ethically not possible in humans. For this reason, model organisms are an...

    Keywords: exerciseenzyme kineticsmetabolite concentrationmodel speciesphysical activity

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    The Impact of Diet and Antibiotics on the Gut Microbiome: Distance Education Variant
    The goal of this article is to describe a variation of an active learning exercise that was previously published by the same author under a similar title. The variation describes modifications...

    Keywords: microbiomenutritionbacterial metabolitesgut bacteriahost response

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    Converting a Face-to-Face Lab to Online: An Example of Process and Outcomes for a CRISPR-Based Molecular Biology Lab
    The COVID-19 pandemic created a need to convert in-person laboratory courses into an online format in a short amount of time. For this reason, we converted our face-to-face molecular biology lab...

    Keywords: mutationtranscriptioncrisprtranslation

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    "Got Algae?" A Sorting Game for Introducing the Weird and Wonderful Diversity of Algae
    Algae are a fascinating and diverse organismal group, with global ecological importance, a storied evolutionary history and deep connections to both contemporary and historical human societies. Yet...

    Keywords: phylogenyBiodiversityphotosynthesisalgaeseaweedmonophyly

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    Assessing in vivo Antimicrobial Activity Through the Analysis of Galleria mellonella Kaplan-Meier Plots
    Antimicrobials and their use in the treatment of bacterial infections are a fundamental lesson in all microbiology courses. Typically, cultivation-based methods are used to teach students about...

    Keywords: Antimicrobial TestingAntimicrobialsInvertebrate animal models

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    Student-Driven Design-and-Improve Modules to Explore the Effect of Plant Bioactive Compounds in Three Model Organisms
    Engaging and supporting introductory level students in authentic research experiences during required coursework is challenging. Plant bioactive compounds attract students' natural curiosity as...

    Keywords: statisticsLabCUREInquiryresearch skillscaterpillardaphniadrugsscience process

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    Breaking Bricks: A Hands-On Model of Enzyme Kinetics and Inhibition
    Enzyme kinetics and the impacts of inhibitors on the enzyme's maximal velocity and ability to bind substrates are important topics in cell biology and biochemistry. However, these topics can be...

    Keywords: kineticsEnzymecompetitive inhibition

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    Online Adaptation to "Gotcha! Which fly trap is the best? An introduction to experimental data collection and analysis"
    We present here a simple and engaging experiment capitalizing on the universal need to rid our homes of fruit flies to teach experimental design and analysis. In an earlier paper, we described an...

    Keywords: data analysisexperimental designolfaction

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    Sorry to Eat and Run: A Lesson Plan for Testing Trade-off in Squirrel Behavior Using Giving Up Densities (GUDs)
    All animals need to find and compete for food, shelter, and mates in order to survive and reproduce. They also need to avoid being eaten by predators. Optimal foraging theory provides a framework...

    Keywords: ecologyanimal behaviorAnimal form and functionAnimal nutritionSquirrel-Net

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    An Introduction to the Squirrel-Net Teaching Modules
    Although course-based undergraduate research experiences (CUREs) are gaining popularity in biology, most are designed for benchwork-based laboratory courses while few focus on field-based skills....

    Keywords: ecologybehaviortrade-offsScientific ProcessSquirrel-Net

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    Squirreling Around for Science: Observing Sciurid Rodents to Investigate Animal Behavior
    Hands-on research experiences are important opportunities for students to learn about the nature of inquiry and gain confidence in solving problems. Here, we present an inquiry-based lesson plan...

    Keywords: foragingbehaviorbehavioral ecologySciuridSquirrelSquirrel-NetTrade-offVigilance

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    Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix
    The extracellular matrix (ECM) provides structural support to cells, but also has key roles in mediating cell adhesion, cell signaling, and differentiation. While this topic is discussed in the...

    Keywords: Neural extracellular matrixPerineuronal netPrimary neuronal culture

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    Exploring the Lytic and Lysogenic Life Cycles of Bacteriophages
    The goal of this lesson is to introduce students to the lytic and lysogenic cycles of T4 and lambda bacteriophages, respectively, using student-centered pedagogies. Bacteriophages are viruses that...

    Keywords: bacteriophagesLysogenic cycleLysogenyLytic cycle

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    Ain't No Mountain Pine Enough: A Case Study of How Mountain Pine Beetles are Affecting Ecosystem Processes
    This case study engages students in generating hypotheses and predictions, analyzing and interpreting data, critically evaluating contrasting results in science, and thinking about feedbacks...

    Keywords: population biologycarbon cyclingSpecies-habitat interactions

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    Adaptation and Facilitation of Small Group Activities in an Online Introductory Biology Class
    In spring 2020, the sudden mid-semester closure of my campus in response to the global COVID-19 pandemic necessitated a rapid transition to emergency online learning. Consequently, I adapted the...

    Keywords: Cellular communicationNeuronal functionNeuronal structure

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    A Quick and Simple Natural Selection Role Play
    Teaching evolution remains a challenging task in biology education. Students enter the classroom with stubborn misconceptions and many traditional examples of the process of evolution may not...

    Keywords: EvolutionfitnessNatural Selectionheritability

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