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    2010-Brian_Winkel-Parameter estimates in differential equation models for chemical kinetics
    We discuss the need for devoting time in differential equations courses to modelling and the completion of the modelling process with efforts to estimate the parameters in the models using data.

    Keywords: kineticschemical kineticszeroth order reactionfirst order reactionsecond order reaction

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    2009-Reid-King-Pendulum Motion and Differential Equations
    This article presents a relatively simple, real-world example that instructors can use in the classroom to let students explore the effect of simplifying assumptions on a model’s ability to reflect...

    Keywords: pendulumphysical pendulum

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    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics...

    Keywords: longitudinal dataAIDSantiretroviral drug therapyBayesian nonlinear mixed-effectstime-varying drug efficacyHIV dynamics

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    2008-Brewer-EtAl-Fitting ordinary differential equations to short time course data
    In this paper, we present a survey of existing algorithms and describe the main approaches. We also introduce and evaluate a new efficient technique for estimating ODEs linear in parameters...

    Keywords: time seriesEvaluation SPLINEgeneleast squaresbifurcation

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    2007-Ramsay-Hooker-Campbell-Cao-Parameter estimation for differential equations-a generalized smoothing approach
    We propose a new method for estimating parameters in models that are defined by a system of non-linear differential equations.

    Keywords: estimating equationfunctional data analysisGauss–Newton methodparameter cascadeprofiled estimationdynamic system

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    2007-Graham-Lerch-Parameter Recovery for a Differential Equation Model
    This article presents a project for a differential equations class using an inverse problem based on the second order differential equation that models and electrical circuit.

    Keywords: laboratorydata collectionRLC circuitinvers problemelectrical circuit

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    2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
    Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.

    Keywords: liverwortsintraveneouspharmacokineticsethanolethanol infustionpharmacodynamictissue model

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    1-125-DiceyPopulation-ModelingScenario
    We offer students an opportunity to generate data for their team on a death and immigration model using 12 and 20 sided dice and then pass on the data to another student team for analysis with a...

    Keywords: simulationimmigrationdeathdice

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    2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
    The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important...

    Keywords: paracetamolpharmacokineticsstomachsmall intestinesulfapyridine

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    2004-Hill-Lozowski-Sampson-Experiments on ice spikes and a simple growth model
    We observed ice-spike growth using time-lapse digital photography, using two water types in two different containers.

    Keywords: iceice spikebulk heat transfermass conservation

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    2002-Dietz-Heesterbeek-Daniel Bernoulli-epidemiological model revisited
    The seminal paper by Daniel Bernoulli published in 1766 is put into a new perspective. After a short account of smallpox inoculation and of Bernoulli’s life, the motivation for that paper and its...

    Keywords: life tableepidemicsmallpoxDaniel Bernoullicompeting riskinoculation

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    2001-Knisley-Kerley-Using data to motivate the models used in introductory differential equations
    In this paper, the data itself is used to motivate mathematical models in introductory mathematics courses. In doing so, various regression and optimization techniques are illustrated.

    Keywords: regressionlogisticTorricelli's Lawgrowthperiodic process

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    1999-Richard_Single-Different quotients-derivatives-and data through modeling with slime
    In this article, I present an experiment that can be conducted in a calculus class to investigate the difference quotient and the derivative, using mathematical modeling with student-collected data.

    Keywords: data analysisslimedifference quotientspread of slime

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    1999-Lomen-Lovelock-Data Sets from text Differential Equations Graphics-Models-Data
    Data selected by field is presented, e.g., chemistry, electricity, growth, motion, population, miscellaneous.

    Keywords: dataEstimate

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    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not...

    Keywords: sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search

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    1984-W_Brunner-D__Focht-Deterministic Three-Half-Order Kinetic Model for Microbial Degradation
    The kinetics of mineralization of carbonaceous substrates has been explained by a deterministic model which is applicable to either growth or nongrowth conditions in soil.

    Keywords: kineticsnonlinear regressionsum of square errorsMonodlinearizemineralizationsubstratescarbonaceous

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    1975-Rodda-Sampson-Smith-The One-Compartment Open Model Parameter Estimation
    A new estimation procedure is proposed for estimating the parameters of the simplest pharmacokinetic model, the one-compartment open model.

    Keywords: compartment modelpharmacokineticsnonlinear estimationone compartment model

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    2011-Brian_Winkel-Parameter_Estimates_in_Differential_Equation_Models_for_Chemical_Kinetics
    We estimate the parameters present in several differential equation models of chemical kinetics and logistic growth.

    Keywords: kineticsparameter estimationlogisticchemical kineticschemical reaction

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    2011-Brian_Winkel-Parameter_Estimates_in_Differential_Equation_Models_for_Population_Growth
    We estimate the parameters present in several differential equation models of population growth, specifically single species exponential and logistic growth, and multiple species competition and...

    Keywords: population modelparameter estimationpopulationparameter

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    1992-Emelie_Kenney-Differential_equations_and_the_AIDS_epidemic
    This paper describes a lecture for Calculus II students in which the Acquired Immune Deficiency Syndrome was used to motivate study of first-order linear differential equations and the derivative...

    Keywords: datafirst orderparameterAIDS

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