You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics
    Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need...

    Keywords: epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

    5775

    views

    1129

    downloads

    0

    comments

    0

    adaptations

    Why do Some People Inherit a Predisposition to Cancer? A small group activity on cancer genetics
    Before undergraduate students take a genetics course they generally know cancer has a genetic basis and involves the proliferation of cells; however, many are uncertain about why only a subset of...

    Keywords: cancerInheritance patternsProbability calculationProto-oncogeneTumor Suppressor Gene

    1724

    views

    440

    downloads

    0

    comments

    0

    adaptations

    Phenology Trends and Climate Change in Minnesota (Project EDDIE): A focus on American elm
    In this module, students will practice answering a specific question about how climate change has affected flowering date in American elm trees.
    800

    views

    421

    downloads

    0

    comments

    0

    adaptations

    Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination
    Sanger sequencing is commonly taught with a hands-on approach. Sanger sequencing involves chain termination by dideoxynucleotides, because they are missing the oxygen on the 3’ carbon atom,...

    Keywords: nucleotidessequencingDNAgel electrophoresisChain Termination

    1057

    views

    209

    downloads

    0

    comments

    0

    adaptations

    Modeling Strep Throat Detection, Infection, and Spread Using an SIR Model and the Vensim Simulation Software
    The overarching goal of this lesson is to provide students with an opportunity to gain experience making and using biological models. Biological modeling can be used to investigate complex,...

    Keywords: infectious diseasebiological modelingSIR model

    1405

    views

    200

    downloads

    0

    comments

    0

    adaptations

    GMC: Genes, Mutations and Cancer - Group Concept Map Development
    It has been shown that active learning strategies used in the classroom can increase student learning and retention of information. We generated an active learning exercise that can be used in the...

    Keywords: mutationcancerCell Division

    2640

    views

    449

    downloads

    0

    comments

    0

    adaptations

    Applying phylogenetic tree building in MEGA X to forensic applications for identifying unknown specimens
    This exercise is designed to guide a learner through the construction of phylogenetic trees as a means of addressing research questions in forensic science such as the identification of previously...

    Keywords: taxonomyBioinformatics and GenomicsDNA Barcodinginvertebrate phylogeneticsforensic entomology

    1713

    views

    567

    downloads

    0

    comments

    0

    adaptations

    Using Dotplots for Comparative Genomic Analysis
    In this activity, students are introduced to dotplots as a tool for analyzing phage genomic similarity.
    1200

    views

    1051

    downloads

    3

    comments

    0

    adaptations

    Introduction to Phylogenetic Trees for Comparative Genomic Analysis
    In this activity, students are introduced to phylogenetic trees and networks as tools for analyzing evolutionary relationships.
    1660

    views

    2126

    downloads

    2

    comments

    0

    adaptations

    Exploring Functions for Common Phage Proteins
    This resource is designed to help students better understand the functions of common structural and enzymatic phage proteins, and to relate these functions to phage structure using electron...
    1108

    views

    1776

    downloads

    0

    comments

    0

    adaptations

    From Dirt to Streptomyces DNA
    The purpose of this semester-long Lesson is to give students an authentic, course-based undergraduate research experience during which they learn basic and advanced microbiological and molecular...

    Keywords: MetabolismAntibiotic productionrRNA genesSecondary metabolitesStreptomyces

    2130

    views

    449

    downloads

    0

    comments

    0

    adaptations

    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

    6316

    views

    1582

    downloads

    0

    comments

    0

    adaptations

    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

    3544

    views

    381

    downloads

    0

    comments

    0

    adaptations

    A Short Bone Biomechanics Primer: Background for a Lesson on Bone Viscoelasticity
    The skeletal system is the first of the body systems that we discuss in-depth in our Physiology & Anatomy courses (PNB 2264/2265 and PNB 2274/2275) in the Department of Physiology and...

    Keywords: structure-functionbiomechanicsAnisotropyViscoelasticity

    712

    views

    108

    downloads

    0

    comments

    0

    adaptations

    Phenology Trends and Climate Change in Minnesota (Project EDDIE)
    In this module, students will practice answering a specific question about how climate change has affected flowering date in American elm trees. Students can then practice on a species of their own...
    1000

    views

    208

    downloads

    0

    comments

    1

    adaptations

    How to Find a Gene: Retrieving Information From Gene Databases
    A strong understanding of distinct gene components and the ability to retrieve relevant information from gene databases are necessary to answer a diverse set of biological questions. However, often...

    Keywords: NCBItranscriptiontranslationGene StructureGene databasesEnsembl

    1431

    views

    337

    downloads

    0

    comments

    0

    adaptations

    It's a Substrate... It's a Protein...No - It's an Enzyme! Teaching Using 3D Serine Protease Physical Modeling Activities to Confront Misconceptions.
    Reported misconceptions of enzyme-substrate interactions highlight the necessity for better, targeted instructional tools and assessments. A series of active learning activities with corresponding...

    Keywords: Protein StructureEnzymes-Substrate InteractionsNoncovalent InteractionsGeometric ComplementaryElectronicsStereochemistrySerine Proteases

    2840

    views

    363

    downloads

    0

    comments

    0

    adaptations

    Making toast: Using analogies to explore concepts in bioinformatics
    Contemporary biology is moving towards heavy reliance on computational methods to manage, find patterns, and derive meaning from large-scale data, such as genomic sequences. Biology teachers are...

    Keywords: bioinformaticsworkflowgenome

    848

    views

    173

    downloads

    0

    comments

    0

    adaptations

    Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches
    Constructing a robust understanding of homologous chromosomes, sex chromosomes, and the particulate nature of genes is a notoriously difficult task for undergraduate biology students. In this...

    Keywords: bioinformaticsautosomehomologous chromosomeshomologous recombinationsex chromosomesex determinationsex reversal mutations

    3193

    views

    655

    downloads

    0

    comments

    0

    adaptations

    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have...

    Keywords: case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections

    1032

    views

    9

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search