You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    Exploring Biological Variation and the Value of Natural History Collections Using an Online Lesson
    First-year science students in large-enrollment lecture courses are rarely given opportunities to contribute to science beyond their classroom as part of their curriculum. Meanwhile, natural...

    Keywords: natural historymuseumBiodiversityalgaeherbariumseaweedcitzen science

    204

    views

    4

    downloads

    0

    comments

    0

    adaptations

    Genotype-phenotype associations: What are they, and how are they related to broader society?
    In this lesson, students will explore contexts in which a single genotype does not directly yield a single phenotype (polygenic traits and gene x environment interactions). Students will reflect on...

    Keywords: journal clubevolution educationInclusive teachinggenotype to phenotypeGenotype-Phenotype Connectionspolygenic traitsgenotype x environment interactions

    279

    views

    24

    downloads

    0

    comments

    0

    adaptations

    Osmosis Through the Lens of Sexual Health
    Osmosis contributes to a range of biological phenomena, from functioning of nephrons in animals to stomatal opening and closing in plants; yet, scientifically simple ideas about osmosis are common....

    Keywords: OsmosisDiffusionsexual healthsocial and cultural embeddedness of scienceinclusive dialogue

    438

    views

    38

    downloads

    0

    comments

    0

    adaptations

    X-ploring Fragile X: The Science Behind the Syndrome
    Fragile X Syndrome is an X-linked genetic disorder resulting from the impairment of transcription of the FMR1 gene, producing less to no FMRP protein. FMRP is a translational inhibitor that plays a...

    Keywords: epigeneticsgene regulationtranscriptioncentral dogmatranslationFragile X syndromeSphingosine Metabolism

    664

    views

    59

    downloads

    0

    comments

    0

    adaptations

    Instructor Guide: Integrating Project Leadership, Artificial Intelligence, Simulation and Google Tools to Understand Regulation of Gene Expression with the Lac Operon and Lactase Gene
    Scientific leadership and current artificial intelligence (AI) skills are important skills to be included in the course curriculum. Together or individually, these skills can enhance knowledge,...

    Keywords: Resources @ HHMI - BioInteractivebiologymolecular biologygenomicsArtificial Intelligencegene expressionleadershipgroup worklactosegoogle toolsSeniorPhET SimulationLactase

    321

    views

    65

    downloads

    0

    comments

    0

    adaptations

    Evaluating Local Adaptation and Conservation with Life Tables
    This module contains a sequence of activities designed for an undergraduate ecology lesson on stage-structured population models or life tables that use published data. Two versions are provided:...

    Keywords: ecologypopulation modelmatrix modelsclimate changelife cyclessensitivity analysispopulation ecologylife tablestage-structured modelsnet reproductive rateconservation planning

    333

    views

    639

    downloads

    1

    comments

    0

    adaptations

    The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics
    Coursework connecting biology to socially relevant issues and ethical questions can help students think about biology in interdisciplinary terms. Gene drives represent one topic involving both...

    Keywords: bioethicsCRISPR/Cas9Genetic modificationGene drives

    439

    views

    67

    downloads

    0

    comments

    0

    adaptations

    Analyzing Data on Behavioral and Immunological Effects of Inflammation in Mice
    In this activity, students will learn about behavioral and immunological responses to a bacterial infection. The activity emphasized the host’s responses rather than bacterial manipulation of the...

    Keywords: Vision and Changedata analysisImmunologybehaviorphysiologyinflammationinterdisciplinary educationAntigenmouseImmunoReachSicknessleukocyteneutrophilLipopolysaccharideacute phase response

    373

    views

    171

    downloads

    0

    comments

    0

    adaptations

    Linkage Analysis
    This Excel workbook simulates a linkage analysis problem with up to four alleles. Based on the offspring produced by a multihybrid testcross, the user builds a model of the gene order,...

    Keywords: recombinationlinkage analysis

    103

    views

    34

    downloads

    0

    comments

    0

    adaptations

    Evolution Through Natural Selection
    This Excel workbook simulates the population genetics of a single gene with two alleles, allowing the user to set the initial allele frequencies and enter parameters for a variety of different...

    Keywords: population geneticsNatural Selection

    106

    views

    44

    downloads

    0

    comments

    0

    adaptations

    Deme 2.0
    This workbook simulates the population genetics of a single gene with two alleles. It can simultaneously model up to three local populations, which may differ in their selection coefficients.

    Keywords: population geneticsGenetic DriftNatural Selection

    110

    views

    80

    downloads

    0

    comments

    0

    adaptations

    DeFinetti 1.0
    This Excel workbook simulates evolution of a single gene with three alleles. The user assigns fitness values to each of the six possible genotypes, then enters starting allele frequencies for each...

    Keywords: population geneticsallelesevolutionary fitness

    99

    views

    46

    downloads

    0

    comments

    0

    adaptations

    Learn biotechnology, biophysics and business through scientific thinking and innovation
    Scientific, leadership and innovation skills are also an integral framework of the curriculum. All of them together or individually are important for enhancement of knowledge, critical thinking,...

    Keywords: educationbusinessBiotechnologybiophysicsleadershiprecombinant DNAgroup workcloninginnovationscientific thinkingplasmid

    258

    views

    135

    downloads

    0

    comments

    0

    adaptations

    Defining Life: Exploring Creativity, Scientific Discovery, and Biology Core Concepts in a Disciplinary First-Year Seminar
    This unit, Defining Life, engages students in thinking like scientists, applying creativity to science, and learning biology core concepts as they explore the defining characteristics of life. This...

    Keywords: Evolutionbiologycellprocess of science

    1256

    views

    65

    downloads

    0

    comments

    0

    adaptations

    Let me in: Interpreting graphs of parasite infection in red blood cells
    The goal of this activity is to familiarize students with reading graphs, to think about how cells are different from one another and how parasites can take advantage of cell surface markers to...

    Keywords: graph interpretationfmnCellsStem cellsmalariaBioGraphIrepresentation in STEMcell sortinginfection efficiencycell surface proteinscell recongitionred blood cells

    257

    views

    169

    downloads

    0

    comments

    0

    adaptations

    A Structured Inquiry-Based Module for the Undergraduate Cell Biology Laboratory That Teaches Fundamental Concepts of Cell Differentiation
    Pedagogical research in science education has shown that students effectively learn science by doing science. As a result, there is increased interest in bringing research-like experiences into the...

    Keywords: fluorescence microscopygene expressionpolymerase chain reactionCell Structurecell culturewestern blottingdifferentiationreverse transcription

    909

    views

    56

    downloads

    0

    comments

    0

    adaptations

    Exploring Microbial Diversity: An Interactive In-Class Assignment for Biology and Microbiology Courses
    This interactive assignment engages students in a hands-on exploration of microbial diversity and the importance of microbes in ecosystems. Designed for General Biology II and Introduction to...

    Keywords: Microbiology EducationMicrobial DiversitymicrobiologyEcological Society of Americaecology educationresearch-based classroom instruction4DEE Framework

    650

    views

    209

    downloads

    0

    comments

    0

    adaptations

    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have...

    Keywords: case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections

    4386

    views

    85

    downloads

    0

    comments

    0

    adaptations

    Learn genomics and bioinformatics through scientific thinking, creation and analysis (virtual and hands-on)
    Nucleic acid are biological molecules composed of nitrogen-containing bases, phosphate groups, and sugar molecules. The complimentary chemical bonding results in formation of double stranded DNA....

    Keywords: data analysisbioinformaticsnucleotidesproteinsRNAgenomicsScientific communicationscientific writingDNAmodelling scientific thinkinggenescientific thinkingcreation

    391

    views

    77

    downloads

    0

    comments

    0

    adaptations

    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

    544

    views

    85

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search