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    Colon Cancer: A Case of Genetic Bad Luck
    Case study developed for an introductory genetics class published in the National Center for Case Study Teaching in Science

    Keywords: bioinformaticsNCBINIBLSEBLASTPublished in National Center for Case Study Teaching in Sciencecolon cancerpedigreegenetic testingAPC

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    Exploring the Introduction of Genetic Variation by Random Mutation: Avida-Ed Lab Book Exercise 1
    An introductory activity introducing the role of random mutation in generating genetic variation using the Avida-ED simulation.

    Keywords: geneticsEvolutionavida-edmutationsoftware simulations

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    Phylogenetic analysis using collections material: interpreting trait evolution by comparison of morphological and molecular genetic hypotheses
    Exercise spans two weeks, includes homework, and involves some groups of animals as well as plants. Emphasizes re-interpretation of morphological trait evolution following molecular genetic...

    Keywords: Evolutionmorphologyphylogenylaboratoryplantsbiological collectionsmolecular analysis

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    Behavioral Genetics: Investigating the genes of a complex phenotype in fruit flies
    Introductory genetics laboratory published as GSA Learning Resource

    Keywords: behaviorbioinformaticsNIBLSEdrosophilagenetic basisfruit fliesmodel organism

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    A Student-Led Hearing on the Use of HeLa Cells in Research
    In this role-playing case study, students will learn about the HeLa cell line and its origins while examining multiple perspectives surrounding the cell line and its uses. The goal of this case...

    Keywords: bioethicsscience policycell culturedebateHeLa cellsinformed consentrole playsocial justice issues

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    SKILLS DEVELOPMENT - Toxicology MSDT
    On this website you can find 6 learning modules on various topics in toxicology. These are self-paced student-centered online learning modules. You will receive a certificate of completion at the...

    Keywords: pathophysiologyregulatory toxicologyprinciples of toxicologybiochemistry and molecular geneticsprinciples of genetic toxicologyapplied systems toxicology

    662

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    Using Bioinformatics to Understand Genetic Diseases: A Practical Guide
    This Practical Guide outlines a number of basic bioinformatics approaches that can be used to understand the molecular basis of genetic diseases.
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    Sickle Cell Disease and Natural Selection in Humans
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    Bacteria Transformation
    TeachEngineering resource in which students construct paper recombinant plasmids to simulate the methods genetic engineers use to create modified bacteria.

    Keywords: bacteriaengineeringGMOsbacterial transformationplasmids

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    Cystic Fibrosis Mechanism and Treatment
    This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymacromoleculesGenetic diseaseCell Structure & Function

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    DNA and Knot Theory
    This module introduces knot theory in the context of understanding the packing of DNA. It is intended for an introductory biology audience.

    Keywords: DNAGenetic InformationTopologyKnot Theory

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    Chi-Square analysis of two point test cross data
    This flash tutorial simulates analysis of a 2 point test cross and will walk you through the analysis of two hypothetical traits.

    Keywords: geneticssimulationchi-squaredlinkagetest crossrecombinationdemonstrationin-class activityproblem set

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    Learning Quantitative Genetics: Investigation of Genetic Control for Cold Stress Response in Plants
    Course-embedded undergraduate research experiences (CUREs) for students have been shown to increase students’ understanding of the process of science, affirm their scientific identity, and...

    Keywords: data analysisrecombinationplantsquantitative geneticsabiotic stress responsegenetic control of complex traitsinheritance of complex traits

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    Exploration of the Human Genome by Investigation of Personalized SNPs
    Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To...

    Keywords: UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization

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    Phylogeography Simulator
    This Excel workbook simulates the phylogeography of an asexually reproducing species.

    Keywords: Phylogeographymutation ratesAsexual reproductionspecies dispersal

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    Examining the Physiology Behind the Symptoms of Lactose Intolerance
    This is a set of extension questions for the HHMI short film The Making of the Fittest: Got Lactase? The Co-evolution of Genes Video Activity.
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    Half Life of mRNA
    This module introduces exponential growth and decay in the context of understanding the stability of mRNA. It is intended for an introductory biology audience.

    Keywords: exponential equationsGenetic Informationlogarithmic equationshalf-lifemRNA

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    Population Bottlenecks: Heterozygosity vs. Allelic Diversity
    This module introduces heterozygosity and allelic diversity in the context of understanding population bottlenecks. It is intended for an introductory biology audience.

    Keywords: Ratiosexponential equationsAlgebraGenetics and Evolution

    854

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    Computational Biology using R
    This is an introductory level course on computational biology.

    Keywords: simulationmoduleRcourseprojectsolutions

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    EvolSeq
    An Excel worksheet that simulates the molecular evolution of DNA sequences.

    Keywords: molecular evolutionDNA

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