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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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    Navigating Bacterial Changes in Aging Organisms: Graphs, Patterns, and Models
    Aging is an incredibly important area of research, and recent biological advances implicate the intestines in aging pathologies. Given that the gut harbors an immense amount of an organism’s...

    Keywords: statisticsgraphingmathematics for life sciencesmathexponential growthPrecalculus

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    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

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    Causes and consequences of resisting herbivory: How long-lived plants avoid damage from diverse short-lived insect herbivores
    This module guides students through decades-long studies of tropical plant-insect interactions to elucidate the ecology and evolution of plant defenses while encouraging students to consider the...
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    Between a rock and a hard place. What can turning rocks tell us about land-use change impacts on animals living in a rock outcrop?
    Unique rock outcrops in the Western Ghats biodiversity hotspot in India provide a setting that challenges students to develop a study to assess the impact of land-use change on threatened animals...

    Keywords: conservationagricultureland useamphibianstropicalbiodiversity losslateritic outcropopen natural ecosystemsreptilesrocks

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    A rainforest with a gold chain? The impacts of gold mining on the trophic web of an Amazonian rainforest of SE Peru
    The use of mercury in artisanal gold mining affects aquatic and terrestrial food webs in the Peruvian Amazon. Learn about bioaccumulation, explore data on mercury deposition in vegetation and how...

    Keywords: conservation biologydeforestationhuman healthpollutionbiodiversity losstropical land use

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    Healing the scars: Tropical rainforest carbon cycling. Does it matter which tree species you plant?
    This online module explores how differences in traits of tropical tree species translate into differential effects on the carbon cycle, integrating ecological information across scales and the...

    Keywords: climate changecarbon cyclingtropical biology4DEE Frameworkforest restorationtropical tree speciessoil carbon

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    EDU-STEM - Equity and Diversity in Undergraduate STEM (RCN-UBE Introduction)
    EDU-STEM is Equity and Diversity in Undergraduate Science, Technology, Engineering and Mathematics (STEM), a network funded by the National Science Foundation to support the research-coordination...

    Keywords: RCN-UBE Introduction

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    2010-Jungck-EtAl-Mathematical Manipulative Models-In Defense of Beanbag Biology
    This paper offers up samples of projects from the Bio- QUEST Curriculum Consortium’s 24-yr experience of holding faculty development workshops for biology and mathematics educators.

    Keywords: epidemiologysimulationinfectious diseasedisease transmissiondiseasein-class activitybean bag activity

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    Who’s That Speci-Mon? Using PokémonTM to Understand Biological Terminology Using Greek and Latin Roots
    We set out to create a fun and engaging activity using recognizable fictional characters, so students get a chance to practice using Greek and Latin roots to create binomial names. Students in...

    Keywords: linguisticstaxonomyAnatomyGreek and Latin Roots

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    1994-T_Gruszka-A_Balloon_Experiment_in_the_Classroom
    The experiment consists of dropping a balloon from two different heights and recording the time it takes to hit the floor. The following experiment involves a balloon, a stopwatch, and a...

    Keywords: differential equationsresistancegravityfree fallaccelerationballoon

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    When tests disagree, how do I know if I have COVID-19?
    Students will learn about infectious disease and the immune response to infection by investigating different types of tests (PCR, antigen, and antibody tests) to detect the SARS-CoV-2 viral genetic...

    Keywords: geneticsVision and Changeintroductory biologyinfectious diseasemolecular biologycore competenciesRT-PCRviruscore conceptsnon-majors biologySARS-CoV-2antibodyAntigenImmunoReachmolecular DiagnosticsCOVID-19 transmission

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    Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students...

    Keywords: gene regulationtranscriptiongene expressioncentral dogmarepressoralternative splicingmRNA processingActivatorTranscription factors

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    Introduction to nucleotide sequence analysis and protein modeling in MEGA and PyMol using coronavirus SARS-CoV-2
    Introduction into computational approaches in phylogeny and protein modeling based on coronavirus SARS-CoV-2 (caused COVID-19 pandemic). Two self-guided tutorials for standard lab classes of 2.5...

    Keywords: phylogeneticsundergraduate educationbioinformaticsNCBICOVID19coronavirusMEGAPyMolvirtual labPDBprotein modelingSARSSARS-CoV

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    Fitting Exponential and Logistic Growth Models to Bacterial Cell Count Data
    In this activity, students will model a noisy set of bacterial cell count data using both exponential and logistic growth models. For each model the students will plot the data (or a linear...

    Keywords: modelingdata analysislinear regressiongraphingExponentsoptimizationcalculusInterpreting GraphsFunctionsqbccCellular and Molecular BiologyChoosing modelsUnderstanding ratesConcepts in Statisticsmeasurementsmanipulating equationscreating graphsExponential and Logarithmic Functionsinterpreting tables

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    The Inside and Outside the Body
    The Inside and Outside the Body activity helps students develop a conceptual understanding of anatomical barriers such as skin and mucus membranes that separate internal cells and fluids from the...

    Keywords: structureAnatomybarriers

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    Plotting Cranial and Spinal Nerve Pathways in a Human Anatomy Lab
    Hands-on experiences with cadavers, animal dissections, or plastic models are effective at improving student learning and attitudes in human anatomy courses. The hands-on experience allows students...

    Keywords: human anatomyNervous systemBrainCranial nerveNerveSpinal cordSpinal nerve

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    That Vertebrate Ate What Exactly?
    During the course of this lesson, students will analyze CT scan data and observe bycatch (or an unknown discovery) captured during the scanning process of vertebrates.

    Keywords: EvolutionidigbioAP Biologynatural history collections3D modelsanatomy and physiology#NGSSVertebrate MorphologyCT scanoVert

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    Teaching introductory bioinformatics with Jupyter notebook-based active learning
    Presentation on teaching introductory bioinformatics with Jupyter notebook-based active learning at the 2019 Great Lakes Bioinformatics Conference

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics
    Coursework connecting biology to socially relevant issues and ethical questions can help students think about biology in interdisciplinary terms. Gene drives represent one topic involving both...

    Keywords: bioethicsCRISPR/Cas9Genetic modificationGene drives

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