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    CYTOSKELETON - Microtubule Dynamics in the Cell Cycle
    This module contains exercises designed to help upper-level cell biology students understand the dynamics of microtubule polymerization and depolymerization within the cell cycle and how cancer...

    Keywords: cell biologyQuantitative reasoningInterdisciplinary STEMInterpreting GraphsCytoskeletonScientific reasoningdimensional analysisNIQBC2. Data and GraphsC6. Quantitative LanguageC1. Numeracy

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    A Simple Method for Predicting a Molecule's Biological Properties From Its Polarity
    The distinction between very polar and less polar substances is a foundation of biochemistry, cell biology, and physiology; it surfaces in multiple concept inventories and elaborations of...

    Keywords: Diffusionsolubilitycovalent bondshydrophilichydrophobicpartition coefficientplasma membranepolarity

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    Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study
    Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut...

    Keywords: dietanimal behaviorimmune systemmicrobiomeNervous systemgut-brain axisImmunoReachdysbiosisCoyoteCytokines

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    Sex Verification Testing of Athletes
    This interactive module explores the biology of sex determination and development in humans, set against the backdrop of the different sex testing policies implemented throughout sports history.

    Keywords: Resources @ HHMI - BioInteractiveDevelopmental BiologyAnatomy & PhysiologyScience & SocietySex hormoneshuman reproductive development

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    Learn Biological Sciences and Chemistry through cellular transport and concentration ( online and hands-on)
    Osmosis is a process by which by which solvent move from a region of lower solute concentration to region of higher solute concentration through a semi-permeable membrane. Cells utilize the process...

    Keywords: statisticsdata analysisbiologycell biologyconcentrationskillscellchemistryOsmosisSpectrophotometersolutionsolutesolvent

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    Teaching Cancer Biology Through a Lens of Social Justice
    The biology classroom is not separate from the greater context of society; social issues can and should be presented in connection with the content. Here we present an example of antiracist...

    Keywords: assessmentcancersocial justicePOGILAlignmentPublic ExamPublic

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    The Evolution of Color Vision in Monkeys: From Nucleotides to Ecology
    This case study examines the evolution color vision in Old World and New World monkeys from multiple biological perspectives.

    Keywords: phylogeneticsgenescase studybiologyResources @ NSF - NCCSTSColor visiondichromatictrichromaticnucleotidesproteinsopsinscell functioncone cellsphotoreceptorsspectral shiftgene duplicationmeiosissex-linkedfood gatheringmonkeysprimatesResources @ QUBES - Teaching & Referenceundergraduate biology education

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    2018-Winkle-Igoshin-Bennett-Josic-Ott-Modeling_Mechanical_Interactions_in_Growing_Populations_of_Rod-Shaped_Bacteria
    Here, we present an agent-based model that allows growing cells to detect and respond to mechanical interactions.

    Keywords: bacteriaagent-basedpopulationbrod-shapedcellular growth

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    Joel E. Greengiant Learns About Peas: From Nucleotides to Selection
    This case study follows purveyors of peas, Joel E. and Jolene Greengiant, as they learn about the origin, biochemistry, genetics and eventual artificial selection of sweet (wrinkled) peas, all in...

    Keywords: geneticspopulation geneticsEvolutionintroductory biologycase studybiologyResources @ NSF - NCCSTSmeiosisMendel’s peaspea plantPisum sativumMendel’s Lawsmolecular geneticsmutationnucleotide insertionartificial selectionstarch synthesisstarch branching enzymeplant domesticationlegumesResources @ QUBES - Teaching & Reference

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    Exploration of the Human Genome by Investigation of Personalized SNPs
    Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To...

    Keywords: UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization

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    Why Cells Change Weight: Demonstrating Linear Regression Through an Osmosis Experiment
    In this activity, students will perform an experiment utilizing dialysis tubing to create cellular models to demonstrate the linear relationship between cell weight and time in varying tonicities....

    Keywords: graphingqbccCellular and Molecular BiologyInterpret graphsConcepts in Statistics

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    Nuclear and Cytoplasmic Viscosity
    This module introduces a modified Stokes-Einstein equation in the context of understanding the difference in viscosity between the nucleus and cytoplasm of cells

    Keywords: linear equationsCell StructureCell GrowthCytoplasmic Viscosity

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    Let me in: Interpreting graphs of parasite infection in red blood cells
    The goal of this activity is to familiarize students with reading graphs, to think about how cells are different from one another and how parasites can take advantage of cell surface markers to...

    Keywords: graph interpretationfmnCellsStem cellsmalariaBioGraphIrepresentation in STEMcell sortinginfection efficiencycell surface proteinscell recongitionred blood cells

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    Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches
    In this four- part guided activity, students will learn about the structure and function of human autosomal and sex chromosomes, view and interpret gene maps, and gain familiarity with basic...

    Keywords: bioinformaticsNIBLSECourseSourceautosomehomologous chromosomeshomologous recombinationsex chromosomesex determinationsex reversal mutations

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    Understanding Gastric Acid Secretion: An Active Learning Approach
    The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the...

    Keywords: diseasesignal transductionAcid SecretionAutonomic Nervous SystemEndocrineGastric PhysiologyGPCRHistology of Gastric Pit

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    Meiosis: A Play in Three Acts, Starring DNA Sequence
    Meiosis is well known for being a sticky topic that appears repeatedly in biology curricula. We observe that a typical undergraduate biology major cannot correctly identify haploid and diploid...

    Keywords: recombinationmeiosisDNA sequenceCrossingoverchromosome structureHolliday junctionhomology

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    Ethics in Synthetic Biology
    This collection of five activities provide students with an introduction to thinking about ethical concerns in human genome synthesis, gene editing, metabolic engineering, and synthetic genomes.

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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    Sperm Motility
    This module introduces equations related to oxygen diffusion in the context of understanding the relationship between oxygen needs and metabolism. It is intended for an introductory biology audience.

    Keywords: OpenStaxAnimal Physiologyparabolic equationssquare root

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    Modeling Strep Throat Detection, Infection, and Spread Using an SIR Model and the Vensim Simulation Software
    The overarching goal of this lesson is to provide students with an opportunity to gain experience making and using biological models. Biological modeling can be used to investigate complex,...

    Keywords: infectious diseasebiological modelingSIR model

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    Exploring the Lytic and Lysogenic Life Cycles of Bacteriophages
    The goal of this lesson is to introduce students to the lytic and lysogenic cycles of T4 and lambda bacteriophages, respectively, using student-centered pedagogies. Bacteriophages are viruses that...

    Keywords: bacteriophagesLysogenic cycleLysogenyLytic cycle

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