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    Enzyme Kinetics: How Quickly Can Acetylcholinesterase Break Up Your Thoughts?
    This module contains exercises designed to help upper-level cell biology students understand the common graphical methods used to evaluate enzyme activity and to see the impact of inhibitors on...

    Keywords: cell biologyQuantitative reasoninginterdisciplinarylinear modelsInterpreting GraphsNIQBC2. Data and GraphsC4. mathematical modelsnonlinear models

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    2017-William_Bialek-Boxes and Arrows To Differential Equations
    This material uses pictures to build kinetic models of reactions and then offers analytic solutions.

    Keywords: Michaelis-MentenEnzymesubstrateDNA\kinetis

    112

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    2015-Sivakumar-EtAl-Approximate Analytical Expression of Concentrations in a Kinetic Model for Biogas Generation from Banana Waste
    The initial value problem in a kinetic model for biogas generation from banana waste is discussed. The model involves the system of non-linear differential equations which has variety of non-linear...

    Keywords: chemical kineticsMichaelis-Menten kineticsanaerobic digestionacidogenic stepsbananamethanogenic stepswastes

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    35

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    2012-Transtrum-Qiu-Optimal experiment selection for parameter estimation in biological differential equation models
    We explore the question to what extent parameters can be efficiently estimated by appropriate experimental selection.

    Keywords: experimental designsystems biologyAssociation & Data Fittingreaction ratesdecay rates

    104

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    2012-Shargel-Yu-AccessPharmacy-Applied Biopharmaceutics and Pharmacokinetics
    Step by step formation of drug absorption models is shown with many good graphics of system and plots. Solutions are offered but no solution methods are shown.

    Keywords: Michaelis-MentenEnzymesubstratecompartmentpharmacokineticsrate constanturinary dataabsorption rate

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    2011-Nguyen-Shi-Modeling the absorption circulation and metabolism of tirapazamine
    This apparently is a student project and it develops the kinetic model, uses Matlab for numerical solution, analytic solution and numerical solution.

    Keywords: absorptionMichaelis-MentenMetabolismdrug metabolismcirculation

    100

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    1977-Michael_Mackey-Leon_Glass-Oscillation and Chaos in Physiological Control Systems
    First-order nonlinear differential-delay equations describing physiological control systems are studied. The equations display a broad diversity of dynamical behavior including limit cycle...

    Keywords: sensitivitychaosparametersRespirationdelayblood cells

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    2007-John_Jungck-Ten_Equations_that_Changed_Biology-Mathematics_in_Problem-Solving_Biology_Curricula The author
    These equations were selected upon the basis of wide-spread recognition of the value of the models.

    Keywords: biologyequationsten equations

    409

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    76

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    Bringing Pasteur Back to Life: Studying the Biochemistry of Yeast Fermentation Through Discussion Groups and an At-Home Lab
    This hands-on, student-centered biochemistry lesson introduces beginner biochemistry students to the techniques of effectively reading and discussing primary literature, identifying fundamental...

    Keywords: primary literatureexperimentationyeastMetabolismFermentationRespirationequilibrium

    3159

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    Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab
    Structure and function are correlated at all levels of biology. This topic is typically addressed early in an undergraduate class in general or molecular biology before students have gained much...

    Keywords: Protein StructureproteaseEnzymechemical bondscatalysissolubility

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    1-093-SucroseReaction-ModelingScenario
    We offer data on the hydrolysis of sucrose in the presence of catalyst sucrase. We present students with several models and ask which model is best. We ask students to estimate parameters for the...

    Keywords: kineticsMichaelis-Mentenhydrolysisreactionsucrose

    178

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    6-019-EnablingEpidemicExploration-ModelingScenario
    We became aware of several interesting possibilities for a modeling opportunity with data and we invited you to explore the several routes to parameter estimation in a SIR model with respect to the...

    Keywords: Akaike Information CriterionMichaelis-Mentenepidemicsaturationgradientleast sum of square errors

    174

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    A 360˚ View of COVID-19
    In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new...

    Keywords: geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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    It's a Substrate... It's a Protein...No - It's an Enzyme! Teaching Using 3D Serine Protease Physical Modeling Activities to Confront Misconceptions.
    Reported misconceptions of enzyme-substrate interactions highlight the necessity for better, targeted instructional tools and assessments. A series of active learning activities with corresponding...

    Keywords: Protein StructureEnzymes-Substrate InteractionsNoncovalent InteractionsGeometric ComplementaryElectronicsStereochemistrySerine Proteases

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    Breaking Bricks: A Hands-On Model of Enzyme Kinetics and Inhibition
    Enzyme kinetics and the impacts of inhibitors on the enzyme's maximal velocity and ability to bind substrates are important topics in cell biology and biochemistry. However, these topics can be...

    Keywords: kineticsEnzymecompetitive inhibition

    3160

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    Unwrapping Enzyme Kinetics
    Enzyme rates and kinetics are key components used by biochemists to understand how enzymes function. However, students often find it difficult to understand how these experiments are performed and...

    Keywords: kineticsstructure-functionenzymescatalysis

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    In-class peer grading of daily quizzes increases feedback opportunities
    Educators are familiar with evidence of the benefit that frequent and immediate feedback provides to our students, regardless of class size. We also often find ourselves in a situation where we do...

    Keywords: foundational knowledgegraphical interpretationtechnical terms

    900

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    Cell Division and the Presence of a Growth Factor
    This module introduces exponential growth, the Michaelis-Menten, and Lineweaver-Burk equations in the context of understanding how growth factors influence cell division. It is intended for an...

    Keywords: exponential equationshyperbolic equationsCell StructureCell Growthgrowth factor

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    Michaelis-Menten Enzyme Kinetics
    In this simulation, equations used in enzyme kinetics (Michaelis-Menten, Eadie-Hofstee, Dixon, and Lineweaver-Burk) are modeled under various conditions.

    Keywords: ExcelResources @ ESTEEMMichaelis-Mentenenzymesenzyme kinetics

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