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    Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
    The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how...

    Keywords: pathwayscancerMolecular AlterationsRetrospective dataTumorigenesis

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    2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
    Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.

    Keywords: liverwortsintraveneouspharmacokineticsethanolethanol infustionpharmacodynamictissue model

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    ModelSim Population Biology Unit
    This resource provides rich student modeling activities and materials, teacher resources, and much more, in the realm of agent based models applied to population biology.

    Keywords: modelingsimulationmoduleEvolutioncase studycurriculumagent-based modelpopulation modeldemonstrationin-class activityPresentation

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    2015-Heiko_Enderling-Integrating experimental data to calibrate quantitative cancer models
    For quantitative cancer models to be meaningful and interpretable the number of unknown parameters must be kept minimal. We focus on a tumor hierarchy of cancer stem and progenitor non-stem cancer...

    Keywords: cancertumorfittingagent-based

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    2006-Ousmane_Mousa_Tessa-Mathematical model for control of measles by vaccination
    In this article, we use a compartmental mathematical model of the dynamics of measles spread within a population with variable size to provide this framework.

    Keywords: vaccinationcompartmentherd immunitymeaslesoptimal strategy

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    2020-Chen_Et_Al-MathModel_Simulation_Phase-Based_Transmissability_Corona_Virus
    In this study, we developed a Bats-Hosts-Reservoir-People transmission network model for simulating the potential transmission from the infection source (probably be bats) to the human infection.

    Keywords: basic reproduction numbercoronavirusnext generation matrixtransmissibilitynovel coronavirus

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    2006-Wilensky-Reisman-Thinking Like a Wolf a Sheep or a Firefly
    We describe a computation-based approach that enables students to investigate the connections between different biological levels using agent-based, embodied modeling tools.

    Keywords: simulationNetLogopredator-preyagent-basedwolffox

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    1-030-EyeModel-ModelingScenario
    We offer a mathematical modeling experience using differential equations to model the volume of an intraocular gas bubble used by ophthalmologists to aid the healing of a surgically repaired region...

    Keywords: retinal surgeryAkaike Information CriterionSpanishsum of square errorssurgeryretionaophthalmologyeyeintraocular gas bubble

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    1-005-OilSlick-ModelingScenario
    We describe a modeling activity with difference and differential equations which enlightens students on the model building process and parameter estimation for a linear, first-order,...

    Keywords: model fittingspreadsheetsSpanishderrame de petróleodatosexpansiónoil slick

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    3-019-ShuttleCockFalling-ModelingScenario
    We are given data on the time and position of a shuttlecock as it falls to the ground from a set height. We attempt to model the falling object and we confront the different resistance terms and...

    Keywords: resistancegravityFree Body Diagramshuttlecockfallingc object

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    3-091-SpringModeling-ModelingScenario
    In this lab students will collect data on their spring mass systems and compare their empirical models to their theoretical ones—giving them an opportunity to actually test a model against data.

    Keywords: datalaboratoryLoggerProVerniermass-spring systemmodel validationempirical modeltheoretical model

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    4-039-FallingDarts-ModelingScenario
    we develop, solve, and analyze a second order differential equation model for free fall incorporating air resistance. Students solve the model using two methods -- reduction of order and...

    Keywords: optimizationresistanceterminal velocitymuzzle velocitydrag coefficientfree fallair drag

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    5-080-SpaceFlightRecolonize-ModelingScenario
    This project is a combination of differential equations, multi-variable calculus, and vector calculus with use of technology to model colonization of a new planet. Students solve a system of...

    Keywords: optimizationsum of square errorsvector calculusLagrange multipliersline integrals

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    6-007-FunctionsAndDerivativesInSIRModels-ModelingScenario
    Given a system of differential equations, how do the solution graphs compare with the graphs of the differential equations? Students tackle this question using SIR models for well-known infectious...

    Keywords: epidemiologyspecies interactionsderivativesvisualizationinfectionSIR modelsLaw of Mass Action

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    6-019-EnablingEpidemicExploration-ModelingScenario
    We became aware of several interesting possibilities for a modeling opportunity with data and we invited you to explore the several routes to parameter estimation in a SIR model with respect to the...

    Keywords: Akaike Information CriterionMichaelis-Mentenepidemicsaturationgradientleast sum of square errors

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    Student-Generated Analogies for Learning about Information Flow
    Using analogies is a standard practice for both teaching and communicating ideas in science. Here we upend the traditional lesson, where the instructor provides a fully constructed analogy and...

    Keywords: critical thinkingcentral dogmaanalogical reasoning

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    Introduction to Quantitative Biology - Fall 2014 Syllabus
    Syllabus for Introduction to Quantitative Biology taught at the College of William and Mary.

    Keywords: quant biosyllabus

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    A Lesson on Matter and Energy at the Organismal Scale: Linking Patterns and Processes Across Diverse Taxa
    Pathways and transformations of energy and matter (PTEM) are a conceptually challenging but essential component of biological literacy. Curricular gaps about PTEM nevertheless remain; although...

    Keywords: plantsenergyAnimalsfungimatterorganismal scale

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    2011-Teleken-EtAl-Mathematical modeling of microbial growth in milk
    A mathematical model to predict microbial growth in milk was developed and analyzed. The model consists of a system of two differential equations of first order. The equations are based on physical...

    Keywords: bacteriadairymilkfood safetymicrobilogy

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    Quantifying Uncertainty and Distinguishing Data Sets in Introductory Physics
    Physics labs are moving increasingly to open-ended experiments where students develop experimental physics skills, rather than verify textbook physics concepts. This sequence of activities sets the...

    Keywords: statisticsMeasurementlaboratoryuncertaintypendulumexperimental skills

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