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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric...

    Keywords: pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy

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    2009-Schaffer-Bronnikova-Controlling malaria
    The present paper reviews potential control strategies from the viewpoint of mathematical epidemiology.

    Keywords: epidemiologymalariabifurcationmosquitotransgenic mosquitoes

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    2009-Munz-EtAl-When Zombies Attack-Mathematical modelling of an Outbreak of Zombie Infection
    We introduce a basic model for zombie infection, determine equilibria and their stability, and illustrate the outcome with numerical solutions.

    Keywords: zombiesinfectionepidemicwater treatmentlatent infectionquarantineimpulsive eradication

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    2006-Wilensky-Reisman-Thinking Like a Wolf a Sheep or a Firefly
    We describe a computation-based approach that enables students to investigate the connections between different biological levels using agent-based, embodied modeling tools.

    Keywords: simulationNetLogopredator-preyagent-basedwolffox

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    2006-Loyd-Wodarz-Drug Resistance in Acute Viral Infections-Rhinovirus as a Case Study
    We develop an epidemiological model that can be used to address the spread of resistance at the population level, and a virus dynamics model that can be used to study the dynamics of virus over the...

    Keywords: stabilityresistancevirusdrugepidemic competitionimmune responserhinovirus

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    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not...

    Keywords: sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search

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    1989-R_Blickhan-Spring Mass Model For Running-Hopping
    A simple spring—mass model consisting of a massless spring attached to a point mass describes the interdependency of mechanical parameters characterizing running and hopping of humans as a function...

    Keywords: spring massjumpjumping

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    1976-JG-Wagner-Computers in pharmacokinetics
    This is a seminal paper in pharmacokinetics in which the author introduces historic notions and approaches. As can be seen from the abstract there is a variety of material here.

    Keywords: kineticscomputerparametersPharmacologydrugspharmacokinetics

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    2018-Robert_Phair-Differential_equation_methods_for_simulation_of_GFP_kinetics_in_non–steady_state_experiments
    Here, we derive new tracer kinetic analytical methods for non–steady state biological systems by constructing mechanistic nonlinear differential equation models of the underlying cell biological...

    Keywords: protein quality controlkineticsCellssteady statechemical kineticsfluouresencephotoactivationinytracellular

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    2017-Thomas_Judson-The_Ordinary_Differential_Equations_Project
    This text is intended for a one-semester undergraduate course in ordinary differential equations. There are additional exercises or computer projects at the ends of many of the chapters.

    Keywords: projectsmathematical modeltextbooktechniquesfreeproofssageTheory

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    2019-Stender_EtAl-Recovery_Of_Differential_Equations_From_Impulse_Response
    In this work, a recent method, which allows reconstructing differential equations from time series data, is extended for higher degrees of automation.

    Keywords: time seriesregressionresponseimpulseoscillationsignal processingsparse regressionsystem identification

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    Venom Diversity & Evolution in Reptiles and Amphibians - An education module for university students
    This module contains information for a three part series introducing the venom system in reptiles and discussing it in an evolutionary context. In the first part venom and its ecological roles are...

    Keywords: geneticsEvolutionecologyHerpetologyAmphibans and ReptilesVenom

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    1-009-Bifurcation-TechniqueNarrative
    We lead students to investigate first-order differential equations that contain unknown parameters. Students discover what happens to the qualitative behavior of solutions to these equations as...

    Keywords: bifurcationqualitative behaviorbifurcation diagram

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    1-190-IntroClass-ModelingScenario
    Students go through development of ideas in mathematical modeling with differential equations. They encounter fundamental ideas of unlimited population growth, limited population growth and a...

    Keywords: population dynamicspredator-preylogisticexponentialgraphical interpretationsqualitative analysis

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    3-001-SpringMassDataAnalysis-ModelingScenario
    We offer data on position of a mass at end of spring over time where the spring mass configuration has damping due to taped flat index cards at the bottom of the mass. Modeling of a spring mass...

    Keywords: datadampingspring-mass systemNewton's Second Law of Motionspring constantHooke's Law

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    5-040-TunedMassDampers-PartII-ModelingScenario
    Studentsbuild mathematical models to mitigate dangerous swaying in structures using structural improvements called Tuned Mass Dampers (TMD). We model the motion of the original structure as a...

    Keywords: structureresistancespring-mass-dashpotearthquakevibrationcontroldampingtuned mass damperstiffnessreduction of vibration

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    6-012-RiverCrossing-ModelingScenario
    Students develop a model of a river crossing in a boat with thrust using Newton's Second Law of Motion from a Free Body Diagram they construct. The model is thence a system of one second order...

    Keywords: dragonNewton's Second Law of Motionriver crossinriver currentvelocity profilethrustFree Body Diagram

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    9-030-WaterHammer-ModelingScenario
    We develop and apply a numerical algorithm that solves a system of two nonlinear partial differential equations (PDEs) that describes the time evolution of the water hammer phenomenon.

    Keywords: Stock and Flow modelhyperbolic equationsfinite differenceswater hammerhydrodynamicscompressibilitywave celerity

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    6-025-WhalesAndKrill-ModelingScenario
    Students will use Excel to observe qualitative behavior in a simulation of a predator-prey model, with blue whales and krill as the predator and prey populations, respectively.

    Keywords: krillwhalepredatpr-prey

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    9-012-PDEGuitarTuning-ModelingScenario
    We lead students through a derivation of a partial differential equation which models the motion of a string held at both ends, a case of the one-dimensional wave equation, and then play it on...

    Keywords: extensionsine wavesfrequencyguitardampingFourierstringtuning

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