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    Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix
    The extracellular matrix (ECM) provides structural support to cells, but also has key roles in mediating cell adhesion, cell signaling, and differentiation. While this topic is discussed in the...

    Keywords: Neural extracellular matrixPerineuronal netPrimary neuronal culture

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    Antibiotic Resistance Genes Detection in Environmental Samples
    Our aim is to provide an authentic research experience for undergraduate students in a variety of biology courses through collaboration between a four-year university and a community college. This...

    Keywords: geneticsenvironmentmicrobiologyUndergraduateantibiotic-resistancePCRgel electrophoresisauthentic inquiry

    2017

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    An Open Source, Collaborative Electronic Notebook for Undergraduate Laboratory Classes
    To overcome many of the limitations of the paper laboratory notebook (PLN), we developed an electronic laboratory notebook (e-LN) for the Dynamic Genome course at the University of California. The...

    Keywords: data collectionData annotationNotebook Skills

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    Sorry to Eat and Run: A Lesson Plan for Testing Trade-off in Squirrel Behavior Using Giving Up Densities (GUDs)
    All animals need to find and compete for food, shelter, and mates in order to survive and reproduce. They also need to avoid being eaten by predators. Optimal foraging theory provides a framework...

    Keywords: ecologyanimal behaviorAnimal form and functionAnimal nutritionSquirrel-Net

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    Honoring the Complexity of Genetics: Exploring the Role of Genes and the Environment Using Real World Examples
    Historically, undergraduate genetics courses have disproportionately focused on the impact of genes on phenotypes, rather than multifactorial concepts which consider how a combination of genes, the...

    Keywords: genesenvironmentMendelQuantitative traitsMultifactorialGene by environment interactions

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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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    Exploring the Lytic and Lysogenic Life Cycles of Bacteriophages
    The goal of this lesson is to introduce students to the lytic and lysogenic cycles of T4 and lambda bacteriophages, respectively, using student-centered pedagogies. Bacteriophages are viruses that...

    Keywords: bacteriophagesLysogenic cycleLysogenyLytic cycle

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    Going Remote: An Online Adaptation to Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix
    In light of the COVID-19 pandemic, instructors have modified materials to transition to a remote learning platform. The challenge for science instructors has been to design lab exercises that...

    Keywords: remote learningExtracellular matrixNeural extracellular matrixPerineuronal net

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    Fostering Student to Student Collaboration Across Institutions in a Protein Centric CURE
    Collaboration is an essential component of research because it allows scientists to share expertise and tackle difficult scientific questions. While many undergraduate science courses include...

    Keywords: communicationBiochemistrycollaborationCUREhypothesisStudent to StudentInter institutionalProtein CentricAssignments

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    Online Adaptation to "Gotcha! Which fly trap is the best? An introduction to experimental data collection and analysis"
    We present here a simple and engaging experiment capitalizing on the universal need to rid our homes of fruit flies to teach experimental design and analysis. In an earlier paper, we described an...

    Keywords: data analysisexperimental designolfaction

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    Forensic Phylogenetics: Implementing Tree-thinking in a Court of Law
    Here we describe an in-class activity developed for Evolutionary Biology and Biodiversity (BioEE1780) at Cornell University, an introductory course required of all biology majors. This activity...

    Keywords: phylogeneticsTree thinkingparaphyly

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    Resources for Assessing Educational Interventions in Biology at the Collegiate Level
    Most scientific research is judged based on the quality of controlled experiments and carefully analyzed results. In addition, proper levels of regulation in terms of biosafety and animal usage are...

    Keywords: researchassessmentpedagogylearning gainsIRBregulatory compliance

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    Building a Model of Tumorigenesis: A small group activity for a cancer biology/cell biology course
    The multistep nature of tumorigenesis is a foundational concept in the context of Cancer Biology. Many students do not appreciate the complex nature of cancer development nor do they understand how...

    Keywords: pathwayscancerMolecular AlterationsRetrospective dataTumorigenesis

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    From Dirt to Streptomyces DNA
    The purpose of this semester-long Lesson is to give students an authentic, course-based undergraduate research experience during which they learn basic and advanced microbiological and molecular...

    Keywords: MetabolismAntibiotic productionrRNA genesSecondary metabolitesStreptomyces

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    Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience
    Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience...

    Keywords: EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs

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    Using CRISPR-Cas9 to teach the fundamentals of molecular biology and experimental design
    One of the challenges of inquiry-based research experiences is balancing the instruction on skills and techniques with data generation and analysis. This is especially true in technique heavy...

    Keywords: experimental designcrisprmolecular technique

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    Investigating Cell Signaling with Gene Expression Datasets
    Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing...

    Keywords: genomicstranscriptionsignaling

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    An active-learning lesson that targets student understanding of population growth in ecology
    Effective teaching and learning of population ecology requires integration of quantitative literacy skills. To facilitate student learning in population ecology and provide students with the...

    Keywords: population growthexponential growthlogistic growthpopulation ecologygrowth rateDensityAbundancecarrying capacitylinear growth

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    You and Your Oral Microflora: Introducing non-biology majors to their “forgotten organ”
    With limited time available for laboratory activities, introductory science courses for non-science majors typically use the laboratory period to reinforce material that was previously presented...

    Keywords: bacteriamicrobiomeBLASTmicrobesDNA replicationPolymerase chain reaction (PCR)

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    Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study
    Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut...

    Keywords: dietanimal behaviorimmune systemmicrobiomeNervous systemgut-brain axisImmunoReachdysbiosisCoyoteCytokines

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