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    Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab
    Structure and function are correlated at all levels of biology. This topic is typically addressed early in an undergraduate class in general or molecular biology before students have gained much...

    Keywords: Protein StructureproteaseEnzymechemical bondscatalysissolubility

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    A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans
    Scientific research experiences are beneficial to students allowing them to gain laboratory and problem-solving skills, as well as foundational research skills in a team-based setting. We designed...

    Keywords: microscopyC. elegansquantitative analysisinquiry-based learninggene expressionRNA interferenceCodon UsageLaboratory Module

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    A Modeling Exercise in Sexual Selection using a Student-Created Bird Species
    Evolution-centered lessons at the undergraduate level can often be jargon-heavy, propagate misconceptions if taught ineffectively, and be uninteresting to students who may not see the relevancy of...

    Keywords: Evolutionfitnesssexual selectionNatural Selectionintersexual selectionmate choice

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    Mock Drug Activity Enhances Student Learning About the Challenges of HIV/AIDS Therapy
    While traditional didactic coursework is important for learning about the scientific aspects of HIV/AIDS, it is difficult to convey social aspects of the epidemic. Due to effective drug therapies,...

    Keywords: drug resistanceRetrovirusViral replication

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    Cladistic Analysis Lesson Using Bats
    Phylogenetic analysis can be a challenging concept to grasp for undergraduate biology students. This cladistic analysis lesson utilizes the amazingly diverse Order Chiroptera as a model to...

    Keywords: batsphylogeny and classificationVertebrate Morphologycladistic analysisbat evolution

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    3-043-BallisticModeling-SpongeDart-ModelingScenario
    The goal of this project is for students to develop, analyze, and compare three different models for the flight of a sponge dart moving under the influences of gravity and air resistance.

    Keywords: projectile motionair resistanceballisticsdimensional analysisNewtonian mechanicssponge dartNerf gunNerf dartBuckingham's Theorem

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    3-027-BobbingDropping-ModelingScenario
    We present two exercises in which we ask students to model (1) falling object experiencing terminal velocity and (2) bobbing block of wood in liquid. We model the motion using Newton's Second Law...

    Keywords: drug resistancedirectedbuoyancyfree fallstatic equilibriumdisplacement

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    3-055-FloatingBox-ModelingScenario
    In this scenario, we lead students through the process of building a mathematical model for a floating rectangular box that is bobbing up and down.

    Keywords: oscillationArchimedes’ Principlebuoancyoscillatory motionNewton's Second Law

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    1-036-NeutralBuoyancy-ModelingScenario
    An object may hang suspended at, say, ten foot depth in a column of water if at ten feet underwater the density of the object equals the density of water. We study this phenomenon

    Keywords: DensitybuoyancyArchimedes’ Principlefloatneutral buoyance

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    3-069-HeatInBar-ModelingScenario
    The temperature distribution along a uniform slender bar due to conduction and convection is investigated through experimental, analytical, and numerical approaches.

    Keywords: heat transferexperimentconductionconvectionboundary conditionsfinite volume method

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    6-021-AcornsRodentsSnakes-ModelingScenario
    Students are given the opportunity to build a three tropic level model in which snakes eat rodents, rodents eat acorns, and acorns grow and occasionally mast.

    Keywords: predationforestsnakesrodentsacornstrophic levelmasting

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    Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students...

    Keywords: gene regulationtranscriptiongene expressioncentral dogmarepressoralternative splicingmRNA processingActivatorTranscription factors

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    Electron Location, Location, Location: Understanding Biological Interactions
    Introductory Biology courses typically introduce the structure and function of biomolecules such as proteins and nucleic acids. To understand biomolecules fully, students require knowledge of...

    Keywords: hydrogen bondshydrophobicity/hydrophilicitypolar and non-polar covalent bonds

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    A How to Guide and Template for Designing a Puzzle Based Escape Room Game
    Educational games are one active and effective way of engaging students with material while also providing additional motivation to tackle challenging concepts. A particularly popular game concept...

    Keywords: Problem SolvingCollaborative WorkCorrect Misconceptions

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    Meiosis Remodeled: Inclusion of New Parts to Poppit Bead Models Enhances Understanding of Meiosis
    A long-standing tradition uses strings of poppit beads of different colors to model meiosis, especially to show how segments of paired homologous chromosomes are recombined. Our use of orthodontic...

    Keywords: meiosischiasma formationchromosome recombination

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    What’s the DEAL – The Digital Encyclopedia of Ancient Life and Digital Atlas Apps
    The Digital Encyclopedia of Ancient Life and Digital Atlas Apps -- identify fossils and explore diversity and history of life on earth.

    Keywords: phylogeneticsdigital resourcesfossilspaleontologyevolutionary biologytaxonomyeduappsnatural history collections3D modelsgeologyopen textbookdigitized natural history collectionsencyclopediaatlasCretaceous World TCNPaleo Niches TCNvirtual teaching collectionFossil field guide

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    How Do Kidneys Make Urine From Blood? Qualitative and Quantitative Approaches to Filtration, Secretion, Reabsorption, and Excretion
    The function of the kidneys is to help maintain a constant internal environment (homeostasis) by regulating the volume and chemical composition of the blood. This regulation occurs via three...

    Keywords: collecting ductexcretionglomerular filtration rate (GFR)nephron tubulereabsorptionrenal corpusclesection

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    A Student-Led Hearing on the Use of HeLa Cells in Research
    In this role-playing case study, students will learn about the HeLa cell line and its origins while examining multiple perspectives surrounding the cell line and its uses. The goal of this case...

    Keywords: bioethicsscience policycell culturedebateHeLa cellsinformed consentrole playsocial justice issues

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    Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course
    A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it...

    Keywords: structure-functionEnzymeallosteric regulationcompetitive inhibitionfeedback inhibitionnoncompetitive inhibitionproductsubstrate

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    Fly Exercise: A Simple Experiment to Test the Physiological Effects of Exercise on a Model Organism
    Model organisms are commonly used to study and experimentally explore biological processes in ways that are technically or ethically not possible in humans. For this reason, model organisms are an...

    Keywords: exerciseenzyme kineticsmetabolite concentrationmodel speciesphysical activity

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