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    Lesson V - Phylogenetics
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson V is an introduction to Phylogenetics.

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    Climate Change Effects on Lake Temperatures (Project EDDIE)
    Students explore new modeling and computing tools while learning fundamental concepts about how climate change will affect lakes

    Keywords: climate changeProject EDDIElakes

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    Geology
    In this video, we discuss how studying the rocks and minerals around us can tell us about the history of the planet. We also discuss what makes a scientific law and how those laws are applied in...

    Keywords: videosgeologyScience Forwardproxiesscientific law

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    Terrestrial Trophic Cascades & Population Structure
    In this activity, students will use data from natural parks to examine trophic cascades.

    Keywords: case studyBiodiversityplantsResource Typetrophic cascadesnational parks

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    Terrestrial Trophic Cascades & Population Structure
    In this activity, students will use data from natural parks to examine trophic cascades.

    Keywords: case studyBiodiversityplantsResource Typetrophic cascadesnational parks

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    Caribbean coral reef structure and biodiversity - Comparing boosted regression tree & multiple regression approaches
    Creating and comparing boosted regression tree models to multiple regression models.
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    Lake Mixing Module (Project EDDIE)
    Students explore spatial and temporal patterns of lake mixing using high-frequency temperature data from lakes around the world.

    Keywords: stratificationProject EDDIE

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    Discovering Prokaryotic Gene Regulation by Building and Investigating a Computational Model of the lac Operon
    The ability to construct and reason through a biological system is an important skill to develop in science education. This level of understanding forces students to recognize the interrelatedness...

    Keywords: prokaryotesgene regulationLac Operoninducible operon

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    A Hands-on Introduction to Hidden Markov Models
    In this Lesson, we describe a classroom activity that demonstrates how a Hidden Markov Model (HMM) is applied to predict a eukaryotic gene, focusing on predicting one exon-intron boundary. This HMM...

    Keywords: transcriptionexonintronsplicing

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    Discovering Prokaryotic Gene Regulation with Simulations of the trp Operon
    The trp operon exemplifies important biological concepts, including the central dogma of molecular biology, feedback inhibition, and gene regulation. For this reason, regulation of the trp operon...

    Keywords: prokaryotesgene regulationattenuationfeedback inhibitionrepressible operontrp operon

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    Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix
    The extracellular matrix (ECM) provides structural support to cells, but also has key roles in mediating cell adhesion, cell signaling, and differentiation. While this topic is discussed in the...

    Keywords: Neural extracellular matrixPerineuronal netPrimary neuronal culture

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    Homologous chromosomes? Exploring human sex chromosomes, sex determination and sex reversal using bioinformatics approaches
    Constructing a robust understanding of homologous chromosomes, sex chromosomes, and the particulate nature of genes is a notoriously difficult task for undergraduate biology students. In this...

    Keywords: bioinformaticsautosomehomologous chromosomeshomologous recombinationsex chromosomesex determinationsex reversal mutations

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    Exploration of the Human Genome by Investigation of Personalized SNPs
    Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To...

    Keywords: UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization

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    Evaluating the Quick Fix: Weight Loss Drugs and Cellular Respiration
    One key to student success in introductory and cell biology courses is a foundational knowledge of cellular respiration. This is a content area in which students often harbor misconceptions that...

    Keywords: data analysisCellular RespirationElectron Transport ChainEnergy transformationsMitochondriaOxidative phosphorylationWeight loss drugs24-dinitrophenol (DNP)

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    DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.
    Advances in high-throughput techniques have resulted in a rising demand for scientists with basic bioinformatics skills as well as workshops and curricula that teach students bioinformatics...

    Keywords: geneticsbioinformaticsDNAgenotypephenotypegenegene annotation

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    How to Design a Classroom Activity that Integrates 3D Print Models with Active Learning
    Student exploration of relevant physical models can deepen knowledge of course material. In this guide we describe a method by which instructors can integrate 3D printing technology with an...

    Keywords: active learning3D print modelsclassroom jigsaw

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    5-040-TunedMassDamper-Part-I-Modeling Scenario
    We offer an opportunity to build mathematical models to mitigate dangerous displacements in structures using structural improvements called Tuned Mass Dampers. We model the motion of the original...

    Keywords: structurespring-mass-dashpotspring massearthquakevibrationtuned mass tunerrestoring forcecontroldampe

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    A CRISPR/Cas Guide RNA Design In Silico Activity
    CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become...

    Keywords: bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

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    A Walk Through the Woods
    Data driven curriculum module from Dryad Digital Repository

    Keywords: ecologygraphingResources @ Dryadhypothesis testingdata visualizationbotanyclimate changeadaptationforestryDryadLabhypothesis formulationenvironmental pressureswood structure and function

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    Understanding Gastric Acid Secretion: An Active Learning Approach
    The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the...

    Keywords: diseasesignal transductionAcid SecretionAutonomic Nervous SystemEndocrineGastric PhysiologyGPCRHistology of Gastric Pit

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