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    Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms
    Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell...

    Keywords: mutationcancertranscriptioncell cycletranslationOncogenesTumor-suppressorp53Transcription factor

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    Integrating Community Ecology Into the Study of Parasites: Exploring the Effect of Host Behavior on Parasite Transmission Rates
    Organismal life cycles are often presented as a set of facts to memorize in undergraduate biology courses. This approach is cognitively demanding for students and fails to convey how central life...

    Keywords: statisticsspecies interactionsQuantitative reasoninggraphsCommunity EcologyParasitologyfood webs

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    A "Box of Lessons" for Exploring Biomolecular Structure and Function
    Biomolecular structure and function is emphasized as a core concept in a variety of community determined educational standards for biology and chemistry. Most curricula introduce students to the...

    Keywords: bioinformaticsproteinsRNADNAmolecular visualizationbiomolecular structurebiomolecular visualizationProtein Data BankPDBMolecular CaseNet FMN

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    1-128-RocketFlight-ModelingScenario
    We offer an opportunity to build a mathematical model using Newton's Second Law of Motion and a Free Body Diagram to analyze the forces acting on the rocket of changing mass in its upward flight...

    Keywords: resistanceFlightRocketrymassNewton's Second Law of MotionthrustFree Body Diagramapexrocket

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    A Laboratory Module That Explores RNA Interference and Codon Optimization Through Fluorescence Microscopy Using Caenorhabditis elegans
    Scientific research experiences are beneficial to students allowing them to gain laboratory and problem-solving skills, as well as foundational research skills in a team-based setting. We designed...

    Keywords: microscopyC. elegansquantitative analysisinquiry-based learninggene expressionRNA interferenceCodon UsageLaboratory Module

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    Mock Drug Activity Enhances Student Learning About the Challenges of HIV/AIDS Therapy
    While traditional didactic coursework is important for learning about the scientific aspects of HIV/AIDS, it is difficult to convey social aspects of the epidemic. Due to effective drug therapies,...

    Keywords: drug resistanceRetrovirusViral replication

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    Role of Crop Genetic Diversity on Pathogen Impact: The Tale of Two Pathogens
    Introductory genetics courses are part of the core curriculum in many different fields, including plant breeding, animal science, biology, microbiology, and natural resource management. Concepts...

    Keywords: plant pathologygenetic diversityDisease TriangleModes of Reproduction

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    Sequences and Properties of Gluten Proteins From Different Grains: A Virtual-Friendly Protein Laboratory
    The COVID-19 pandemic has forced much university instruction into virtual modes. As a result, many laboratory courses have either dropped content altogether or replaced hands-on activities with...

    Keywords: protein structure and functionProtein sequenceintermolecular forcesBiomacromolecules

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    Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?
    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    Keywords: course based undergraduate research experiencesBLASTmolecular modelingSARS-CoV-2antibodyNextstrainiCn3DSequence alignmentStructure alignment

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    Exploring the bottom of the ocean and TITANIC wreckage with David Gallo
    In honor of @WorldOceansDay , we had the privilege of talking with legendary oceanographer David Gallo for our latest Lunch With A Scientist episode. He shares astonishing footage of deep-sea...

    Keywords: Oceanographyocean exploration

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    1-082-MirroMirror-ModelingScenario
    This project models the ``Foucault Knife Edge Test,'' an optical test commonly used by amateur astronomers who make their own mirrors for reflecting telescopes. The goal of the test is to estimate...

    Keywords: astronomymirror climate change mitigation ocean deacidificationopticstelescopelensFoucaultinterpolation

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    1-058-WaterClocks-ModelingScenario
    We apply Torricelli's Law to the task of building a water clock in which the height of the water in a container falls at a constant rate when the container has a hole in the bottom to let the...

    Keywords: flowTorricelli's Lawspigotswater clock

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    1-059-ContainerShapeFallingWater-ModelingScenario
    We examine many different physical situations to determine the time it takes a fixed volume of water to flow out of different shape containers through the same size exit hole at the bottom of the...

    Keywords: containersTorricelli's Lawshapedischarge coefficient

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    1-067-ModelingWithSigmoidCurves-ModelingScenario
    The assignment considers two well-known models of population growth, Verhulst-Pearl and Gompertz models, for which qualitative and quantitative analyses are provided. The graphs of the...

    Keywords: logisticGompertzsigmoidVerhulst-Pearl

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    1-105-AnimalFall-ModelingScenario
    This project uses Newton's Second Law of Motion to model a falling animal with a resistance term proportional to cross sectional area of the animal, presumed to be spherical in shape.

    Keywords: animalNetwon's Second Law of Motionfalling bodyterminal velocityair resistanceNewtonair frictionfall

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    1-053-SlimeSpread-ModelingScenario
    We offer a video showing real time spread of a cylinder of slime and challenge students to build a mathematical model for this phenomenon.

    Keywords: spreadsheetsslime

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    Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students...

    Keywords: gene regulationtranscriptiongene expressioncentral dogmarepressoralternative splicingmRNA processingActivatorTranscription factors

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    Electron Location, Location, Location: Understanding Biological Interactions
    Introductory Biology courses typically introduce the structure and function of biomolecules such as proteins and nucleic acids. To understand biomolecules fully, students require knowledge of...

    Keywords: hydrogen bondshydrophobicity/hydrophilicitypolar and non-polar covalent bonds

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    The BioTAP Professional Development Model: Expanding Empirical Research on Graduate Student Teaching Professional Development
    The Biology Teaching Assistant Project (BioTAP) provides a year-long mentoring program for practitioners and researchers of Biology Graduate Teaching Assistant Teaching Professional Development...

    Keywords: mentoringstemcommunityUndergraduateteaching professional developmentGraduate Teaching AssistantConfidence in Research Skills

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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