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    Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter
    While there are several available lessons for teaching introductory biology students about diffusion, facilitated diffusion, and active transport, fewer materials exist to support upper-division...

    Keywords: DiffusionActive transportfacilitated diffusionNecessary and sufficientTransport proteins

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    Design Your Own Flow Cytometry Experiment: A Four-Week Inquiry Laboratory
    Due to its importance to the field, flow cytometry should be one of the hallmark methods a student learns in the lab portion of an undergraduate immunology course. Flow cytometry is a classic lab...

    Keywords: Immunologyexperimental designFlow cytometryMice

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    Using Immunocytochemistry and Fluorescence Microscopy Imaging to Explore the Mechanism of Action of Anti-Cancer Drugs on the Cell Cycle
    Understanding and visualizing the cell cycle and mitosis is an essential concept of cell biology. This multi-week lab module has students investigate the mechanism of action of anti-cancer drugs...

    Keywords: fluorescence microscopymitosisCell StructureCell ImagingImmunocytochemistryQuantitative microscopySTEM skills

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    Predicting and classifying effects of insertion and deletion mutations on protein coding regions
    Mutations in genes can affect the encoded proteins in multiple ways, and some of these effects are counterintuitive. As for any other knowledge, students must create their own deep understanding of...

    Keywords: mutationcentral dogmatranslationframeshift

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    Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course
    A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it...

    Keywords: structure-functionEnzymeallosteric regulationcompetitive inhibitionfeedback inhibitionnoncompetitive inhibitionproductsubstrate

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    Investigating Gene Expression and Cell Specialization in Axolotl Embryos
    The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most...

    Keywords: developmenttranscriptiongene expressionmodel organismembryo

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    Implementing active learning approaches into an upper-division biology course
    In this essay, we present our strategy for implementing active learning strategies into an upper division course on Human Genetics. Our principal goal was to shift from a traditional didactic...

    Keywords: human biologyPedigree analysisRare genetic diseases

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    Who’s That Speci-Mon? Using PokémonTM to Understand Biological Terminology Using Greek and Latin Roots
    We set out to create a fun and engaging activity using recognizable fictional characters, so students get a chance to practice using Greek and Latin roots to create binomial names. Students in...

    Keywords: linguisticstaxonomyAnatomyGreek and Latin Roots

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    Medical Student Opinions of a Gross Anatomy Course Aided with Prosection
    Dissection manuals and color atlases are useful tools in the anatomy lab, but do not provide the important three-dimensional (3-D) relationships between structures. For the first time at the...

    Keywords: Gross AnatomyStructure function relationMorphological variationProsected specimen as teaching tool

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    Using the Cell Engineer/Detective Approach to Explore Cell Structure and Function
    As instructors of introductory biology courses for majors and non-majors, we have struggled with teaching the concept of cell structure and function in an engaging way.  However, this is a...

    Keywords: cell functionCell StructureCellular diversityDynamic cellular functionOrganelle function

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    Using genomic data and machine learning to predict antibiotic resistance: a tutorial paper
    Antibiotic resistance is a global public health concern. Bacteria have evolved resistance to most antibiotics, which means that for any given bacterial infection, the bacteria may be resistant to...

    Keywords: Tutorialmachine learningantibiotic-resistanceArtificial Intelligence

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    Green Infrastructure/Green Roofs (Project Eddie)
    Runoff in urban areas is an increasingly important issue when it comes to water quality. It is a major hydrologic issue in New York City, as urban infrastructure creates excess runoff and...

    Keywords: climate changeProject EDDIEWater cycle

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    TuNE-BIO - Transforming Assessment, Feedback, and Grading in Undergraduate Biology Education (RCN-Introduction)
    The aim of TUnE-BIO is to transform assessment, feedback, and grading practices in undergraduate biology classrooms to combat “weed-out” culture and decrease inequities. Our incubator year focused...

    Keywords: RCN-UBE Introduction

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    The River Field Studies Network: Connecting rivers, people, & science through immersive field-based education (RCN-UBE Introduction)
    Connecting rivers, people, & science through immersive field-based education

    Keywords: RCN-UBE Introduction

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    Green Infrastructure/Green Roofs (Project Eddie)
    Runoff in urban areas is an increasingly important issue when it comes to water quality. It is a major hydrologic issue in New York City, as urban infrastructure creates excess runoff and...

    Keywords: climate changeProject EDDIEWater cycle

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    Green Infrastructure/Green Roofs (Project Eddie)
    Runoff in urban areas is an increasingly important issue when it comes to water quality. It is a major hydrologic issue in New York City, as urban infrastructure creates excess runoff and...

    Keywords: climate changeProject EDDIEWater cycle

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    Prairie Eco Services (Project EDDIE)
    As densely populated urban areas continue to expand, human activity is removing much-needed greenspaces from our communities; in turn, we are also removing critical buffers that are needed to...

    Keywords: Project EDDIEWater cycle

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    COVID-19: Molecular Basis of Infection-ADAPTATION
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

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    Molecular Basis of Sickle Cell Disease
    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    Keywords: Hemoglobinmolecular visualization and analysisintroductory bioinformaticssickle cell diseasePDBMolecular Case Studyoxygen bindingmyoglobinmolecular literacy3D protein structuresstructural representations

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    Island biogeography, spatial ecology, and macroinvertebrate species diversity in Richmond’s rock pools
    Students investigate questions of community ecology and biogeography using data from an urban rock pool ecosystem. Using ArcGIS 10, students learn to create effective maps, calculate landscape...

    Keywords: aquatic macroinvertebratesCommunity Ecologyspecies diversityGeographic Information System (GIS)spatial analysisJames River

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