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    Cells of the Immune System
    This tutorial provides an overview of the immune system, concentrating on the roles played by B and T lymphocytes, and on the antigen-presentation system.
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    2017-Allali-EtAl-Mathematical Modeling of the Adaptive Immune Responses in the Early Stage of the HBV Infection
    The aim of this paper is to study the early stage of HBV infection and impact delay in the infection process on the adaptive immune response, which includes cytotoxic T-lymphocytes and antibodies.

    Keywords: logisticHBV infectionadaptive immunie responseT-lymphocytes

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    Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts
    Lesson on what it means for biological processes to be Poissonian, published in CourseSource

    Keywords: quantitative biologybioinformaticsmicrobiologyphysicsNIBLSEHIVCourseSourcemultiplicity of infectionPoisson Distribution

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    Antigen presentation and cytotoxic T lymphocytes (CTLs): elucidating a common roadblock for students
    Active learning resource for pre-Nursing anatomy and physiology lecture explaining antigen presentation to CTLs and how the CTLs recognize and destroy the pathogen using Biointeractive animations...

    Keywords: Resources @ HHMI - BioInteractiveimmune systemAnatomy & PhysiologyCell communication

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    Using the IEDB to Predict Proteasomal Cleavage Events and T-cell Epitopes
    Research experiences provide a valuable view into the world of science and a great way to explore new fields and careers while developing critical thinking skills. The development and maintenance...

    Keywords: biologydatabaseImmunologydata sciencebioinformaticsBiotechnologyt-cellengineeringantibodyBioengineeringAntibody EngineeringlymphocytesProteinNetChopepitopeIEDBB-cellProteasomeProteasomal Cleavage

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    Spreadsheet Tutorial 4: t-Test
    Calculate t-values and perform t-tests using built-in functions.

    Keywords: Resources @ HHMI - BioInteractiveScientific ProcessStatistics and MathScientific Methodology

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    Infectious Chocolate Joy with a Side of Poissonian Statistics: An activity connecting life science students with subtle physics concepts
    Introductory physics courses are required for many programs in the life sciences, yet traditional curricula fail to help students meaningfully connect physical concepts with biological...

    Keywords: quantitative biologyHIVmultiplicity of infectionPoisson DistributionPhysics for biologists

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    2011-W_Wood-Squigonometry
    The differential equations used to define a unit circle, namely x’(t) = - y(t), y’(t) = (t), x(0) = 1, y(0) = 0 are generalized to produce interesting functions which...

    Keywords: Trigonometric Functionscirclesquigonometryinverse functiontrigonmetry

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    2011-W_Wood-Squigonometry
    The differential equations used to define a unit circle, namely x’(t) = - y(t), y’(t) = x(t), x(0) = 1, y(0) = 0 are generalized to produce interesting functions which...

    Keywords: TrigonometryTrigonometric Functionsparametric equationscirclesinecosinesquigonometryinverse function

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    6-017-OncolyticViruses-ModelingScenario
    Students explore oncolytic virotherapy using systems of differential equations and numerical simulations.

    Keywords: cancercancer-immune dynamicsimmune suppressor drugoncolytic virusvirotherapy

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    Chapter 8: Comparing two means: the t-test
    Biostatistics Using R: A Laboratory Manual was created with the goals of providing biological content to lab sessions by using authentic research data and introducing R programming language....

    Keywords: biostatisticsR programming language

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    1-009-ICUSpread-ModelingScenario
    We offer students the opportunity to model the percentage of voluntary nonprofit hospitals in the United States with Intensive Care Units during the period of 1958-1974.

    Keywords: logisticsum of square errorsIntensive Care Unithospitalspread

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    Garden peas and cabbage plants: A short 'de-simplified genetics' activity
    Are plants of genotype T/T tall? Are those of genotype t/t short? Let's find out in this short activity entirely based on a segment of: Smith's (2014) "It’s Not Your Grandmother’s Genetics Anymore!"

    Keywords: geneticsintroductory biologyclickersenvironmentplantsin-class activitygenotypephenotypeMendel

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    2008-Yang-EtAl-Differential Equation Model of HIV Infection of CD T-Cells with Delay 
    Abstract: An epidemic model of HIV infection of CD4+ T-cells with cure rate and delay is studied. We include a baseline ODE version of the model, and a differential-delay model with a discrete time...

    Keywords: virusT cellsHopf bifurcationendemic equilibrium

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    Flatten the Curve Course Module
    JavaScript isn't enabled in your browser, so this file can't be opened. Enable and reload.Some Word features can't be displayed in Google Docs and will be dropped if you make changesView...
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    3-015-StyrofoamBallFall-ModelingScenario
    We are given data on a falling Styrofoam ball and we seek to model this motion.

    Keywords: footballresistancegravityfalling bodysum of square errorsNewton's Second Law of Motionsum of forcesstyrofoam

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    5-025-SaltCompartments-ModelingScenario
    Model a phenomena in which salt mixtures from two tanks are mixed using several strategies.

    Keywords: compartmentsalttanks

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    Spreadsheet Data Analysis Terms and Shortened Tutorial 4
    Introductory students are asked to learn terms for descriptive statistics and complete a matching exercise. Tutorial 4 was shorted to just the full calculations of t values.

    Keywords: Scientific ProcessStatistics and MathScientific Methodology

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    1-025-MixingItUp-ModelingScenario
    Students build three different models for levels of salt in a tank of water and at each stage the level of complexity increases with attention to nuances necessary for success.

    Keywords: compartmentsalttankmixing

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    2002-Nelson-Perelson-Mathematical analysis of delay differential equations models of HIV-1 infection
    We develop and analyze a set of models that include intracellular delays, combination antiretroviral therapy, and the dynamics of both infected and uninfected T cells.

    Keywords: infectionHIVT cells

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