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    Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?
    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    Keywords: course based undergraduate research experiencesBLASTmolecular modelingSARS-CoV-2antibodyNextstrainiCn3DSequence alignmentStructure alignment

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    Linking Intermediate Disturbance Hypothesis to Traditional Ecological Knowledge and Conservation
    Traditional Ecological Knowledge is based on deep understanding of systems from observations made over hundreds to thousands of years. This resource connects Traditional Ecological Knowledge to...

    Keywords: climate changeenvironmental justiceintermediate disturbance hypothesisTraditional ecological knowledge

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    1-005B-ChemDataCollection-ModelingScenario
    A chemistry graduate student is collecting data on a chemical reaction and does a poor job of collecting the data. Indeed, he only collects the data at the start and end of a number of three minute...

    Keywords: kineticslaboratoryorder of reactionchemical reactionchemical datainfusion

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    1-044-CollegeBound-ModelingScenario
    Preparing for four years of college for a friend of the family's newborn is the task. Making assumptions about costs, timing, interest rates, and fiscal capabilities are the order of the day.

    Keywords: interest ratecollege savingtuitionroom and board

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    1-005A-ChemDataCollection-ModelingScenario
    A student is assigned the task of collecting data on a chemical reaction and does a poor job of collecting data. She only collects data at the start and end of a number of ten minute intervals and...

    Keywords: linear regressionkineticschemistryorder of reactionchemical reactionchemical datainfusiondifferencing

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    1-001s-StochasticMDeathImmigration-ModelingScenario
    We develop a mathematical model of a death and immigration process using m&ms as a stochastic process with the help of probability generating functions (pgf). We start with 50 m&ms in a bag.

    Keywords: simulationdatalogisticimmigrationstochasticdeathfitting

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    1-190-IntroClass-ModelingScenario
    Students go through development of ideas in mathematical modeling with differential equations. They encounter fundamental ideas of unlimited population growth, limited population growth and a...

    Keywords: population dynamicspredator-preylogisticexponentialgraphical interpretationsqualitative analysis

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    3-071-WirelessTelegraphy-ModelingScenario
    This project has three parts, (1) done at home, (2) and (3) in class. In (1) we recall how to solve second order differential equations with constant coefficients and simple source functions. In...

    Keywords: bRLC circuitresonancebeatscurrentwireless telegraphyLC circuit

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    5-015-RunnersSynchronize-ModelingScenario
    In this modeling scenario we practice finding and classifying equilibria of a one-variable differential equation. We do this in the context of a phase model which is often a simpler way of studying...

    Keywords: predatorAutonomous equationsoscillationcoupled oscillatorsynchronyrunnerpreyKuramato model

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    5-023-FakingGause-ModelingScenario
    We use a fake or toy data set to permit discovery of the parameters in a two population protozoan model used to study paramecium and yeast competition in the 1930's studies of G. F. Gause in the...

    Keywords: competitionlogisticyeastGauseparameciumpoplulation

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    5-025-SaltCompartments-ModelingScenario
    Model a phenomena in which salt mixtures from two tanks are mixed using several strategies.

    Keywords: compartmentsalttanks

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    6-067-LotkaVolterra-ModelingScenario
    This modeling scenario guides students through the process of fitting the Lotka-Volterra model of two differential equations to a real time series observational data. Students use the capabilities...

    Keywords: time seriesdatacompetitionLotka-Volterramodel fittingpredictiongauseRexperimental

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    6-028-SaltCompartments-ModelingScenario
    Model a phenomena in which salt mixtures from two tanks are mixed with changing volumes of water.

    Keywords: concentrationcomparmentsalttankmixing

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    Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students...

    Keywords: gene regulationtranscriptiongene expressioncentral dogmarepressoralternative splicingmRNA processingActivatorTranscription factors

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    Electron Location, Location, Location: Understanding Biological Interactions
    Introductory Biology courses typically introduce the structure and function of biomolecules such as proteins and nucleic acids. To understand biomolecules fully, students require knowledge of...

    Keywords: hydrogen bondshydrophobicity/hydrophilicitypolar and non-polar covalent bonds

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    Exploring Health Inequities and Redlining
    For this assignment, students will investigate relationships between historic redlining data and modern statistics of human health.

    Keywords: diseasehealthsocial justicepublic healthData science for Biologistredliningchronic diseasesocial vulnerability

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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    A How to Guide and Template for Designing a Puzzle Based Escape Room Game
    Educational games are one active and effective way of engaging students with material while also providing additional motivation to tackle challenging concepts. A particularly popular game concept...

    Keywords: Problem SolvingCollaborative WorkCorrect Misconceptions

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    Teaching Advanced Concepts in Regulation of the Lac Operon With Modeling and Simulation
    Success in biochemistry and other life science courses requires that students understand important biological concepts. One of these concepts is how gene regulation ensures that homeostasis is...

    Keywords: gene regulationinducible operonProkaryotic cellPhosphoenolpyruvate transferase system (PTS)

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    "I Really Enjoy These Annotations:" Examining Primary Biological Literature Using Collaborative Annotation
    Critically reading and evaluating claims made in the primary literature are vital skills for the future professional and personal lives of undergraduate students. However, the formal presentation...

    Keywords: Stem cellsAdult neurogenesisCRISPR gene editing

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