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    Keywords: High School

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    X-ploring Fragile X: The Science Behind the Syndrome
    Fragile X Syndrome is an X-linked genetic disorder resulting from the impairment of transcription of the FMR1 gene, producing less to no FMRP protein. FMRP is a translational inhibitor that plays a...
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    Adapting a Traditional Laboratory Exercise to Become Inquiry Based: An Example With an Introductory Biology Lab in Diffusion
    Authentic research experiences are effective in fostering self-efficacy and increasing retention in STEM, particularly among minoritized student populations. Many instructors have sought to bring...
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    Evaluating Local Adaptation and Conservation with Life Tables
    This module contains a sequence of activities designed for an undergraduate ecology lesson on stage-structured population models or life tables that use published data. Two versions are provided:...
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    Environmental Injustice: When the Grass is Greener on the Other Side
    Environmental pollution is a global threat that is especially prevalent in heavily industrialized and urbanized areas. Pollution can be found in many forms, such as natural and synthetic pollutants...
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    Two-Species Model
    These two Excel worksheets simulate the population growth of two interacting species. In isolation, each species grows logistically, but interaction effects between species may limit or enhance...
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    Split Decomp
    This Excel worksheet performs split decomposition on a set of four DNA sequences and their associated amino acid sequences. The user can type in the sequences or paste them in from a text file.
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    Phylogeography Simulator
    This Excel workbook simulates the phylogeography of an asexually reproducing species.
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    Operon
    This Excel workbook models lac operon function in a partial diploid E. coli. The user chooses the bacterial genotype and the sugars present in the surrounding medium: the workbook then determines...

    Keywords: Lac OperonE. coli

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    Linkage Analysis
    This Excel workbook simulates a linkage analysis problem with up to four alleles. Based on the offspring produced by a multihybrid testcross, the user builds a model of the gene order,...
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    Hidden Markov Model
    Hidden Markov models are a set of mathematical tools that can be used to draw inferences about genomic and evolutionary processes.
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    GeoPhyl
    This Excel workbook allows students to explore evolution over space and time using published data on the invasive plant Tamarix (salt cedar).
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    Genetic Code
    This Excel workbook allows the user to recreate the steps in breaking the genetic code. The user enters the sequence of repetitive synthetic mRNA strands, which are translated in vitro to produce...

    Keywords: mRNAgenetic code

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    Dynamic Programming
    In bioinformatics, dynamic programming is mainly used to align nucleotide and amino acid sequences, and to predict RNA and protein folding from primary sequence data.
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    Deme 2.0
    This workbook simulates the population genetics of a single gene with two alleles. It can simultaneously model up to three local populations, which may differ in their selection coefficients.
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    DeFinetti 1.0
    This Excel workbook simulates evolution of a single gene with three alleles. The user assigns fitness values to each of the six possible genotypes, then enters starting allele frequencies for each...
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    Continuous Growth Models
    This Excel worksheet compares user-input growth data with predictions under linear, exponential, and logistic models of growth. Introduces concepts of statistical analysis that can be additionally...
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    Biostatistical Tools
    This Excel collection of workbooks has tools for: 1. Linear regression through the origin 2. Linear regression not through the origin 3. Polynomial fit 4. A simple chi-square analysis to test...
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    Using genomic data and machine learning to predict antibiotic resistance: a tutorial paper
    Antibiotic resistance is a global public health concern. Bacteria have evolved resistance to most antibiotics, which means that for any given bacterial infection, the bacteria may be resistant to...
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    BioGraphI FMN Leader Guide (Template version) - Google Docs
    This document contains the leader guide for the Biologist and Graph Interpretation (BioGraphI) Project’s semester-long Faculty Mentoring Network (FMN). FMN leaders use it to organize the FMN, and...
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