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    2012-Shargel-Yu-AccessPharmacy-Applied Biopharmaceutics and Pharmacokinetics
    Step by step formation of drug absorption models is shown with many good graphics of system and plots. Solutions are offered but no solution methods are shown.

    Keywords: Michaelis-MentenEnzymesubstratecompartmentpharmacokineticsrate constanturinary dataabsorption rate

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    2011-Nguyen-Shi-Modeling the absorption circulation and metabolism of tirapazamine
    This apparently is a student project and it develops the kinetic model, uses Matlab for numerical solution, analytic solution and numerical solution.

    Keywords: absorptionMichaelis-MentenMetabolismdrug metabolismcirculation

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    2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
    This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.

    Keywords: concentrationphysiologydrugslag timeExtravascularPharamacokineticspeak time

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    2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
    We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.

    Keywords: QUBES Leadership Teamparametersabsorptionbifurcationpharmacokineticscalciumcognitive decline

    141

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    1971-Carl_Metzler-Usefulness Of Two Compartment Open Model In Pharmacokinetics
    Compartment models are widely used in pharmaceutical research to quantitate the kinetics of absorption, distribution, metabolism and excretion of a drug. In this article two applications of the two...

    Keywords: LSDcompartmentpharmacokinetics

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    5-001-LSD-ModelingScenario
    We describe the use of a two compartment model of a linear system of first order linear differential equations to model lysergic acid diethylamide (LSD) in the body. We provide the data from the...

    Keywords: LSDSpanishcompartmentpharmacokineticslysergic acid diethylamide

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    Energy Absorbed from Light During Photosynthesis
    This module introduces how energy absorption from light is affected by the wavelengths in the context of understanding photosynthesis. It is intended for an introductory biology audience.

    Keywords: plant physiologyRatiosphotosynthesishyperbolic equationsOpenStax

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    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.

    Keywords: absorptioncompartmentbloodstreamplasmapharmacokineticsdrugpharmacodynamics

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    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.

    Keywords: absorptioncompartmentbloodstreamplasmapharmacokineticspharmacodynamicstherapeutic concentration rangedrug dispositiondrug response

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    5-020-ParacetamolAbsorption-ModelingScenario
    We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and...

    Keywords: paracetamolanalgesicvegetariannon-vegetarian

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    1-114-EarthClimate-ModelingScenario
    In this modeling scenario, we investigate the Earth's climate using a zero-dimensional energy balance model. Energy balance models are climate models that try to predict the average surface...

    Keywords: climateenergytemperaturelinearizationphase linesenergy balance modelroot finding

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    The Biology of Skin Color
    This film explores the hypothesis that different tones of skin color in humans arose as adaptations to the intensity of ultraviolet radiation in different parts of the world.

    Keywords: Resources @ HHMI - BioInteractivegene regulationgene expressionAnatomy & Physiologyhuman evolutionfilm

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    Water Movement through a Membrane: The Van't Hoff Equation
    This module introduces the van't Hoff equation in the context of understanding the metabolic activity of the epithelial cells lining the stomach. It is intended for an introductory biology audience.

    Keywords: AlgebraInequalitiesCellular Processes

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    Pain Medication Treatment Modeling Project
    This classroom modeling project applies mathematical techniques to solve a problem related to drug dosage patterns. Suitable for high school or undergraduate students. Prerequisite: Calculus I.

    Keywords: Mathematical Biologycalculusexponential decayrecursionabsorptionelimination

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    2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
    The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important...

    Keywords: paracetamolpharmacokineticsstomachsmall intestinesulfapyridine

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    5-011-ModelingIbuprofren-ModelingScenario
    We consider modeling of data from a clinical experiment administered as oral doses of 400 mg ibuprofen, an analgesic pain reliever. Concentrations of ibuprofen in the serum/plasma of the subjects...

    Keywords: dataAICAkaike Information Criterionabsorptionsum of square errorscompartment modelibuprofendelay

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    Geoscience Methods and Resources for K-5 Pre-Education Majors
    : Exploring Geoscience Methods was an excellent capstone experience for Elementary Education Majors. The class I used this module with was 24 students of various backgrounds and academic...

    Keywords: geneticsvideosQUBESecologyResources @ HHMI - BioInteractiveMathematical Biologycalculusjavaorganismal biologyquantitative biologybioinformaticsneurosciencegenomicscancerSecondaryyoutubemicrobiomeFaculty Mentoring NetworksalamanderCapture mark-recaptureAudience level - Introductory UG - majorsAudience level - Introductory UG - non-majorsecosystemsgenetic basis of diseasebiology of cellshuman reproductionfood chainIntroduction to Modelingrandom number generatorPost-secondaryLower DivisionPossible TasksModeling ProjectBuildCompareEvaluateexponential decayrecursionabsorptionelimination

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    Promoting Climate Change Literacy for Non-majors: Implementation of an atmospheric carbon dioxide modeling activity as an inquiry-based classroom activity
    Students who are directly involved in scientific activities develop a deeper understanding and appreciation of both scientific knowledge and the scientific process. This understanding is critically...

    Keywords: modelingExcelquantitativeclimate changeEnvironmental Biologyatmospheric carbon dioxide

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    A Case Study for Teaching Toxicology: Using Whales as an Indicator for Environmental Health
    One of the challenges of teaching scientific courses is helping students understand research methods, biological models, and data analysis, which can be especially difficult in classes without a...

    Keywords: absorptionone environmental health hypothesismetals

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    The Inside and Outside the Body
    The Inside and Outside the Body activity helps students develop a conceptual understanding of anatomical barriers such as skin and mucus membranes that separate internal cells and fluids from the...

    Keywords: structureAnatomybarriers

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