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    2017-Allali-EtAl-Mathematical Modeling of the Adaptive Immune Responses in the Early Stage of the HBV Infection
    The aim of this paper is to study the early stage of HBV infection and impact delay in the infection process on the adaptive immune response, which includes cytotoxic T-lymphocytes and antibodies.

    Keywords: logisticHBV infectionadaptive immunie responseT-lymphocytes

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    Cells of the Immune System
    This tutorial provides an overview of the immune system, concentrating on the roles played by B and T lymphocytes, and on the antigen-presentation system.
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    Sickle Cell Disease and Natural Selection in Humans
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection
    Article presenting evidence that the bitter taste receptor T2R38 regulates the mucosal innate defense of the human upper airway.
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    Venom Diversity & Evolution in Reptiles and Amphibians - An education module for university students
    This module contains information for a three part series introducing the venom system in reptiles and discussing it in an evolutionary context. In the first part venom and its ecological roles are...

    Keywords: geneticsEvolutionecologyHerpetologyAmphibans and ReptilesVenom

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    Antigen presentation and cytotoxic T lymphocytes (CTLs): elucidating a common roadblock for students
    Active learning resource for pre-Nursing anatomy and physiology lecture explaining antigen presentation to CTLs and how the CTLs recognize and destroy the pathogen using Biointeractive animations...

    Keywords: Resources @ HHMI - BioInteractiveimmune systemAnatomy & PhysiologyCell communication

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    Sickle Cell Disease Case Study
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    2015-Zhang-EtAl-On the Selection of ODE Models with Application to Predator-Prey Dynamical Models
    We propose a computationally inexpensive approach that employs statistical estimation of the full model, followed by a combination of a least squares approximation (LSA) and the adaptive Lasso.

    Keywords: least-squares approximationSpline modelingMonte Carlo simulationsvariable selectionadaptive LASSO

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    Lizard Evolution Series Collection
    The species of Anolis lizards of the Caribbean provide a living example of evolution and speciation.

    Keywords: geneticsEvolutionResources @ HHMI - BioInteractivebehaviororganismal biologySpeciationDNAphylogeny and classificationHigh School

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    Exploring Population Change without Selection: Avida-Ed Lab Book Exercise 4
    An introductory activity exploring how a population changes without natural selection using the Avida-ED simulation.

    Keywords: population geneticsEvolutionavida-edsoftware simulationsSelection

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    2008-Luis_San_Andrés-Dynamic Response of Second Order Mechanical Systems with Viscous Response Forces
    Walk through the cases in context of second order linear constant coefficient differential equation with driving function

    Keywords: driving functionviscousmechanical system

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    2014-Niemann-Miklos-Simple Method for Estimation of Parameters in First Order Systems
    A simple method for estimation of parameters in first order systems with time delays is presented in this paper.

    Keywords: delaytime delystep response

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    2014-John_Cimbala-Dynamic System Response
    In this learning module, we discuss the dynamic system response of sensors and their associated electronic circuits.

    Keywords: sensor networksoscillationssystem responseelectronic circuit

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    Type I Functional Response
    This module introduces the type I functional response in the context of understanding the relationship between an individual's rate of consumption and food density. It is intended for an...

    Keywords: ecologylinear equationsfood density

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    3-105-FrequencyResponse-ModelingScenario
    We describe the frequency response to a second order differential equation with a driving function as the maximum steady state solution amplitude and perform some analyses in this regard.

    Keywords: transient dynamicscircuitspring massdriverfrequency responseamplitudesteady state

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    To Vaccinate or Not to Vaccinate
    To vaccinate or not to vaccinate, that is the question. Much of the recent trend in society against vaccination is that the general population does not understand 1) how vaccines work and 2) how...

    Keywords: pathogenELISAimmunityantibodyAntigen

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    2019-Fred_Brauer-The_Final_Size_of_a_Serious_Epidemic
    In an epidemic of a serious disease, there is likely to be behavioral response that decreases the epidemic size considerably.

    Keywords: epidemicfinal sizebehavioral responseSIER modelrelations

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    Type II Functional Response: Holling’s Disk Equation
    This module introduces the Holling’s disk equation in the context of understanding the relationship between an individual's rate of consumption and food density. It is intended for an introductory...

    Keywords: ecologyHolling's Disk Equation

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    Gratitude Interventions in a Biology Course to Foster Student Persistence and Success
    College students are experiencing a mental health crisis, which has been further exacerbated by the COVID-19 pandemic. This is problematic because stress and anxiety impede learning. One way to...

    Keywords: mental healthgratitudepositive psychologydegree commitment

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    DeFinetti 1.0
    This Excel workbook simulates evolution of a single gene with three alleles. The user assigns fitness values to each of the six possible genotypes, then enters starting allele frequencies for each...

    Keywords: population geneticsallelesevolutionary fitness

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