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    The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics
    Coursework connecting biology to socially relevant issues and ethical questions can help students think about biology in interdisciplinary terms. Gene drives represent one topic involving both...

    Keywords: bioethicsCRISPR/Cas9Genetic modificationGene drives

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    Analyzing Data on Behavioral and Immunological Effects of Inflammation in Mice
    In this activity, students will learn about behavioral and immunological responses to a bacterial infection. The activity emphasized the host’s responses rather than bacterial manipulation of the...

    Keywords: Vision and Changedata analysisImmunologybehaviorphysiologyinflammationinterdisciplinary educationAntigenmouseImmunoReachSicknessleukocyteneutrophilLipopolysaccharideacute phase response

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    A Journal Club Project to Promote Interpreting and Presenting Information From the Primary Scientific Literature
    Many undergraduate students receive little guidance on how to critically read, interpret data within, or present information from the primary scientific literature before they begin senior...

    Keywords: primary literaturejournal clubScience CommunicationfeedbackPeer reviewgroup workOral presentationProcess skillsPeer evaluationDevelopmental neurobiology

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    Glycolysis Can Be Fun: Rediscovering Glycolysis as a Problem-Solving Introduction to Metabolism
    A thorough understanding of glycolysis forms a foundation for students to analyze subsequent topics in metabolism, a core competency recognized by multiple national societies for biology and...

    Keywords: Problem based learningPOGILenzymesGlycolysisMetabolismFermentationchemical reactionsCard sorting activityCofactors

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    Malaise Trap Project: Involving Undergraduate Students in Network Science
    A multi-week project for upper division undergraduate students to participate in network-level science, while simultaneously learning classic entomology skills of specimen collection and...

    Keywords: entomologynetwork science4DEE Framework

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    Two-Species Model
    These two Excel worksheets simulate the population growth of two interacting species. In isolation, each species grows logistically, but interaction effects between species may limit or enhance...

    Keywords: population growthcompetition modelsLotka-Volterra

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    Protein Analysis
    This Excel workbook allows the analysis of sample or imported protein sequences. The model can analyze protein sequences up to 500 amino acids long.

    Keywords: Protein sequencehydrophobicity/hydrophilicity

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    Pharmacokinetics
    This Excel module explores how drugs are processed and absorbed in the human body.

    Keywords: drug metabolismpharmacokinetics

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    Linkage Analysis
    This Excel workbook simulates a linkage analysis problem with up to four alleles. Based on the offspring produced by a multihybrid testcross, the user builds a model of the gene order,...

    Keywords: recombinationlinkage analysis

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    Leslie/Lefkovitch Matrix Models for Age or Stage-structured Populations
    This Excel workbook uses the Leslie matrix model for population projection of age-class structured populations, and also allows Lefkovitch matrix models for stage-class structured populations.

    Keywords: survivalpopulation ecologyfecundityLeslie matrixeigenvalueseigenvectorsLefkovitch matrixage-class structured populationsstage-class structured populationsreproductive value

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    Hidden Markov Model
    Hidden Markov models are a set of mathematical tools that can be used to draw inferences about genomic and evolutionary processes.

    Keywords: hidden markov models

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    Deme 2.0
    This workbook simulates the population genetics of a single gene with two alleles. It can simultaneously model up to three local populations, which may differ in their selection coefficients.

    Keywords: population geneticsGenetic DriftNatural Selection

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    Database Construction and Sampling
    Creating your own database is an excellent way for students to learn the trials and tribulations of data collection and management. Construction of three simple databases using a spreadsheet is...

    Keywords: databasesdata managementdata collectiondata ethicsdata integrity

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    COVID-19 Model
    This Excel worksheet implements an SEAIHRD model for Covid-19 (Susceptible, Exposed, Asymptomatic infective, symptomatic Infective, Hospitalized infective, Recovered, Deceased).

    Keywords: infectious diseaseCOVID19

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    Continuous Growth Models
    This Excel worksheet compares user-input growth data with predictions under linear, exponential, and logistic models of growth. Introduces concepts of statistical analysis that can be additionally...

    Keywords: exponential growthlogistic growthcurve fittinglinear growthgrowth models

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    Biological Cellular Automata Laboratory (BioCA Lab)
    This Excel module includes both linear cellular automata and 2D cellular automata. The original 3 rules for survival, death, and birth are implemented in this module, but users with some Excel...

    Keywords: cellular automata

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    Biodiversity
    Biodiversity allows the diversity of a biological population to be estimated with both the Shannon and Simpson biodiversity indices based on information theory.

    Keywords: Shannon diversity indexSimpson diversity indexBiodiversity indicesInformation theory

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    Science Learning Spaces in undergraduate courses ( virtual and face to face) : Impact of Technology, Resources and Active Learning Activities
    Science Learning Spaces are evolving in both face to face and virtual learning environments. Effective utilization and identification of appropriate learning spaces helps in formation of engaging...

    Keywords: resourcesstemfaculty developmentUndergraduatesciencetechnologyWorkshop materialAnalysislearning spacescience learning spacemajor learning spaceminor learning spacelearning activitiesthinking

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    3D FractaL-Tree
    3D FractaL-Tree allows scientists to collect data from actual specimens in the field or laboratory, insert these measurements into a spatially explicit L-system package, and then visually compare...

    Keywords: fractalsL-systems

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    Luria-Delbruck
    These two workbooks model the evolution of phage resistance in a bacterial population under two alternative hypotheses.

    Keywords: phageLuria-Delbruckresistance

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