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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Green Infrastructure/Green Roofs (Project Eddie)
    Runoff in urban areas is an increasingly important issue when it comes to water quality. It is a major hydrologic issue in New York City, as urban infrastructure creates excess runoff and...

    Keywords: climate changeProject EDDIEWater cycle

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    Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway
    Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions.  This...

    Keywords: SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    Students require a deep understanding of the central dogma before they can understand complex topics such as evolution and biochemical disorders. However, getting undergraduate biology students to...

    Keywords: Protein Structurecomputational modelingcentral dogmaplant leaf structurePhenotype/Genotype

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    Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course
    Metagenomics is rapidly evolving due to advances in sequencing technologies and bioinformatics, but without proper training to interpret these datasets, student understanding remains limited. Aimed...

    Keywords: microbiome

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    1-137-SheepGraze-ModelingScenario
    In this activity, students will apply graphical analysis (such as phase lines) to determine the long-term predictions of a differential equation model for pasture grass using two different formulas...

    Keywords: herbivoreplantphase linesbifurcationoverexploitationsheepgraze

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    Biodiversity research using digitized, internet-based natural history collections
    Collections based research is a critical tool for organismal biology and biodiversity research. Yet natural history collections have a complicated past. This multi-class module examines the...

    Keywords: natural historycollectionsdigital resourcesOERBiodiversitynatural history museumsdigital collectionsbirdsBiodiversity Collections Network (BCoN)BLUE

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    The Polar Bear of the Salt Marsh?
    National Center for Case Study Teaching in Science- in this interrupted case study, students follow a young naturalist as she explores why saltmarsh sparrows are increasingly rare in coastal...

    Keywords: Coastal wetlandsConnecticutmanagementnortheastsea-level risesalt marsh

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    Seed Dispersal, Mutualisms, and Communities
    In this activity, students use data from published studies to understand patterns of seed dispersal and apply these ideas to understanding the evolution of mutualisms, and how mutualistic...

    Keywords: mutualismsecologyResources @ HHMI - BioInteractivecommunityplantsdiversityScientific Processlarge lecture

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    2007-I-Liang_Chern-Mathematical Modeling and Differential Equations
    In this course, I will mainly focus on, but not limited to, two important classes of mathematical models by ordinary differential equations: • population dynamics in biology • dynamics in...

    Keywords: population dynamicsecologydynamicsclassical mechanicschemical reaction

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    A Case Study for Teaching Toxicology: Using Whales as an Indicator for Environmental Health
    One of the challenges of teaching scientific courses is helping students understand research methods, biological models, and data analysis, which can be especially difficult in classes without a...

    Keywords: absorptionone environmental health hypothesismetals

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    Assessing in vivo Antimicrobial Activity Through the Analysis of Galleria mellonella Kaplan-Meier Plots
    Antimicrobials and their use in the treatment of bacterial infections are a fundamental lesson in all microbiology courses. Typically, cultivation-based methods are used to teach students about...

    Keywords: Antimicrobial TestingAntimicrobialsInvertebrate animal models

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    Osmosis: Determination of the rate of osmosis and the isotonic concentration
    This module contains exercises designed to help students understand how solute concentrations affect the direction and rate of osmosis. Students are given different scenarios to predict the...

    Keywords: introductory biologyQuantitative reasoninginterdisciplinarycell functionOsmosisNIQBC2. Data and GraphsC4. mathematical modelsC6. Quantitative LanguageC1. NumeracyC5. Logic and Algorithms

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    Enzyme Kinetics: How Quickly Can Acetylcholinesterase Break Up Your Thoughts?
    This module contains exercises designed to help upper-level cell biology students understand the common graphical methods used to evaluate enzyme activity and to see the impact of inhibitors on...

    Keywords: cell biologyQuantitative reasoninginterdisciplinarylinear modelsInterpreting GraphsNIQBC2. Data and GraphsC4. mathematical modelsnonlinear models

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    2002-Patrick_Nelson-Alan_Perelson-Mathematical_analysis_of_delay_differential _equation_models_of_HIV-1_infection
    Models of HIV-1 infection that include intracellular delays are more accurate representations of the biology and change the estimated values of kinetic parameters when compared to models without...

    Keywords: delayHIV-1T cellscombination antiviral therapy

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    1-128-RocketFlight-ModelingScenario
    We offer an opportunity to build a mathematical model using Newton's Second Law of Motion and a Free Body Diagram to analyze the forces acting on the rocket of changing mass in its upward flight...

    Keywords: resistanceFlightRocketrymassNewton's Second Law of MotionthrustFree Body Diagramapexrocket

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.

    Keywords: bioinformaticsNIBLSEProtein StructureDNAmolecular modelinggenotypephenotypeCourseSourcecomputational modelingcentral dogmaplant leaf structure

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    Datasets for Whitlock & Schluter's "The Analysis of Biological Data"
    Link to data sets used in The Analysis of Biological Data . All data are in CSV format.

    Keywords: The Analysis of Biological DataResources @ QUBES - Data

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    My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships
    To facilitate understanding of the fundamental genetic concept of the genotype-phenotype relationship in our introductory biology students, we designed an engaging multi-week series of related...

    Keywords: gel electrophoresissequence analysiscanine geneticsdeoxyribonucleic acid (DNA)dog coat morphologygenotype and phenotypemutationsPolymerase chain reaction (PCR)single nucleotide polymorphism (SNP)

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    Bioimage Informatics Activity
    Students use basic bioimage informatics techniques to acquire quantitative data from images of cultured cells and test a hypothesis about the effect of a genetic mutation on cellular phenotypes

    Keywords: geneticsResources @ HHMI - BioInteractivegenomicscancergenetic basis of diseasebiology of cells

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    Analysis of Microbiomes Using Free Web-Based Tools in Online and In-Person Undergraduate Science Courses
    Our understanding of microbiomes, or the collection of microorganisms and their genes in a given environment, has been revolutionized by technological and computational advances. However, many...

    Keywords: microbiomeDNA SubwayCyVerseCourse based undergraduate researchQIIME2ranacapa

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