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    2017-Bonin-EtAl-Mathematical modeling based on ordinary differential equations - promising approach to vaccinology
    As a proof of concept, we developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data...

    Keywords: immune systemyellow fevercomputational immunologycomputational vaccinology

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    2016-Bonin-EtAl-Mathematical modeling based on ordinary differential equations-vaccinology
    We developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data available in the literature.

    Keywords: Immunologyimmune systemAntigenvaccinologyyellow fever

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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric...

    Keywords: pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy

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    2008-Ribbing-EtAl-Mathematical models of diabetes progression
    Writing a good model for diabetes progression is difficult because the long time span of the disease makes experimental verification of modeling hypotheses extremely awkward. underlying the

    Keywords: physiologyclinical trialsdiabetesdiabetes progression

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    2007-Ramsay-Hooker-Campbell-Cao-Parameter estimation for differential equations-a generalized smoothing approach
    We propose a new method for estimating parameters in models that are defined by a system of non-linear differential equations.

    Keywords: estimating equationfunctional data analysisGauss–Newton methodparameter cascadeprofiled estimationdynamic system

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    2007-Exben_Friis-Jensen-Modeling and Simulation of Glucose-Insulin Metabolism
    In this thesis one of the models of diabetes, Bergman’s minimal model is described trough derivation and simulations.

    Keywords: Metabolisminsulin resistanceglucosePID controllerintolerance

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    1-025-MixingItUp-ModelingScenario
    Students build three different models for levels of salt in a tank of water and at each stage the level of complexity increases with attention to nuances necessary for success.

    Keywords: compartmentsalttankmixing

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    1999-Meade-Struthers-Differential Equations in the New Millennium-The Parachute Problem
    The parachute problem will be used to illustrate several essential features of the improved courses. In particular, it will be seen that the traditional version of the parachute problem is not very...

    Keywords: resistancefree fallparachutejumpskydiving

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    1971-Boyes-Scott-Jebson-Godman-Julian-Lidocaine in Man
    Plasma levels of lidocaine were measured in 5 normal male volunteers following both intravenous and oral administration of the drug.

    Keywords: pPharmacologypharmacokineticslidocaine

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    1979-Brian_Winkel-Elementary_My_Dear_Watson_Differential_Equation
    Sherlock Homes explains to Doctor Watson how he solves a murdermystery using Newton's Law of Cooling.

    Keywords: Newton's Law of CoolingSherlock Holmestime of detah

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    2019-Stender_EtAl-Recovery_Of_Differential_Equations_From_Impulse_Response
    In this work, a recent method, which allows reconstructing differential equations from time series data, is extended for higher degrees of automation.

    Keywords: time seriesregressionresponseimpulseoscillationsignal processingsparse regressionsystem identification

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    Introducing Immunology Research Literature to Understand B-cell Receptor Gene Expression
    Immunology is relevant to our everyday lives, driving a need for more engaging and inclusive undergraduate immunology education. One way to engage a diverse group of learners is by teaching them...

    Keywords: recombinationantibodyV(D)J recombinationB-cell receptorlymphocyte receptor

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    Hypoxia in Coastal Marine Ecosystems (Project Eddie) - Modified
    Aquatic ecosystems are home to a complex intersection of physical and biological factors and an intersection of natural and anthropogenic factors. In the Chesapeake Bay, low oxygen events have...

    Keywords: OceanographyProject EDDIEEutrophication

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    1-052-SaltWaterTanks-ModelingScenario
    We offer three mixing problems, of increasing order of difficulty, in which salt is coming into a tank of water and upon instantaneous mixing is leaving the tank.

    Keywords: salttankmixing

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    1-074-BottleWaterFlow-ModelingScenario
    We offer an experiment in which data is collected to ascertain a parameter in the differential equation formulation of Torricelli's Law for water flow.

    Keywords: bwaterTorricelli's Lawbottle

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    1-105-AnimalFall-ModelingScenario
    This project uses Newton's Second Law of Motion to model a falling animal with a resistance term proportional to cross sectional area of the animal, presumed to be spherical in shape.

    Keywords: animalNetwon's Second Law of Motionfalling bodyterminal velocityair resistanceNewtonair frictionfall

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    5-020-ParacetamolAbsorption-ModelingScenario
    We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and...

    Keywords: paracetamolanalgesicvegetariannon-vegetarian

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    Hypoxia in Coastal Marine Ecosystems (Project Eddie)
    Aquatic ecosystems are home to a complex intersection of physical and biological factors and an intersection of natural and anthropogenic factors. In the Chesapeake Bay, low oxygen events have...

    Keywords: OceanographyProject EDDIEEutrophication

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    Sequence Similarity: Introducing Biological Databases to Community College Biology Students
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsincubatorsBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogramZika virus

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    Developing a phylogram from computational resources.
    This laboratory module, published on CourseSource, leads introductory biology students in the exploration of a basic set of bioinformatics concepts and tools.

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBINIBLSEalgorithmsBLASTmultiple sequence alignmentsequence similarityneighbor-joining distance matrixCourseSourcephylogrampercent identity matrix

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