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    Design Your Own Flow Cytometry Experiment: A Four-Week Inquiry Laboratory
    Due to its importance to the field, flow cytometry should be one of the hallmark methods a student learns in the lab portion of an undergraduate immunology course. Flow cytometry is a classic lab...

    Keywords: Immunologyexperimental designFlow cytometryMice

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    Using CRISPR-Cas9 to teach the fundamentals of molecular biology and experimental design
    One of the challenges of inquiry-based research experiences is balancing the instruction on skills and techniques with data generation and analysis. This is especially true in technique heavy...

    Keywords: experimental designcrisprmolecular technique

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    The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups
    Students have difficulty understanding synaptic integration in neural circuits, and how spatial and temporal summation combine in a target neuron to reach threshold.  This Lesson uses small...

    Keywords: neuron physiologyspatial summationsynaptic integrationtemporal summationthreshold

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    Using Place-Based Economically Relevant Organisms to Improve Student Understanding of the Roles of Carbon Dioxide, Sunlight, and Nutrients in Photosynthetic Organisms
    Biology students require broad preparation for diverse careers including agriculture, natural resource management, and laboratory research. Concurrent with this need, employers are seeking...

    Keywords: energyphotosynthesisbiomass

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    Undergraduates Learn Evolution Through Teaching Kindergartners About Blind Mexican Cavefish
    The development and implementation of a scientific outreach activity comes with a number of challenges. A successful outreach event must match the sophistication of content to the audience, be...

    Keywords: Evolutionecologymorphologysensory biologycave biologycomparative biologyenvironmental differencesregressive lossstructure and function

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    Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers
    Most introductory genetics courses cover genetic linkage, a core concept in the CourseSource genetics learning outcome framework. Although it is a classical genetics topic, genetic linkage remains...

    Keywords: meiosisphenotypegel electrophoresismicrosatellitesBanding PatternGenetic linkageInheritanceMolecular MarkersPhysical Linkage

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    Evaluating Representation in Science Through a Peer-Reviewed Research Study
    The demographic representation of scientists featured in biology curricular materials do not match that of the undergraduate biology student population or of the U.S. population. In this lesson, we...

    Keywords: societyRepresentationSTEM equity

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    Helping Students to Metacognitively Read Scientific Literature With Talking to the Text
    Reading primary scientific literature enhances students’ understanding of material, increases their self-efficacy, and critical thinking skills. However, scientific articles often present...

    Keywords: scientific literaturereading comprehensionmetacognitionScience process skillsTalking to the TextDense Scientific Texts

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    Why Do I Need a Lab Notebook? Teaching Responsible Conduct of Research with CURE Lab Notebooks
    There are few instructional tools about data acquisition and management available for undergraduate students. I created this lesson as a Fellow of the Ethics Network for Course-Based Opportunities...

    Keywords: lab notebookresponsible conduct of researchdata acquisition/ management

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    Simulating Cortical Rotation, Axis Induction, and Experimental Embryology in Amphibian Embryos Using Clay Models
    The study of development requires learners to understand spatially complex concepts like embryo anatomy. Embryo anatomy is dynamic over time, and it is often manipulated by researchers in...

    Keywords: developmentXenopusfertilizationEmbryologyinductionSymmetry breakingOrganizerCortical rotationPatterning

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    Transitioning Two-Stage Exams to an Online Class
    Students often find biology courses to be very difficult and isolating, particularly if they identify as part of a group that has been historically excluded from STEM. Some of this anxiety and...

    Keywords: lower division STEMupper division STEM

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    Metastatic Mastery: A Case and Game-Based Approach to Learning About Cancer Mechanisms
    Mechanisms that contribute to the development of cancer are numerous and complicated, though most can be traced to a set of mutations in cell cycle regulatory genes that throw the process of cell...

    Keywords: mutationcancertranscriptioncell cycletranslationOncogenesTumor-suppressorp53Transcription factor

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    Responsible and Ethical Conduct of Research: Instruction on Plagiarism
    Helping students understand where they should provide citations in research manuscripts is an essential aspect of training them in the responsible and ethical conduct of research. This Lesson...

    Keywords: citationwritingethicsplagiarismparaphrasequote

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    A Modeling Exercise in Sexual Selection using a Student-Created Bird Species
    Evolution-centered lessons at the undergraduate level can often be jargon-heavy, propagate misconceptions if taught ineffectively, and be uninteresting to students who may not see the relevancy of...

    Keywords: Evolutionfitnesssexual selectionNatural Selectionintersexual selectionmate choice

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    How Do Kidneys Make Urine From Blood? Qualitative and Quantitative Approaches to Filtration, Secretion, Reabsorption, and Excretion
    The function of the kidneys is to help maintain a constant internal environment (homeostasis) by regulating the volume and chemical composition of the blood. This regulation occurs via three...

    Keywords: collecting ductexcretionglomerular filtration rate (GFR)nephron tubulereabsorptionrenal corpusclesection

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    Understanding Gastric Acid Secretion: An Active Learning Approach
    The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the...

    Keywords: diseasesignal transductionAcid SecretionAutonomic Nervous SystemEndocrineGastric PhysiologyGPCRHistology of Gastric Pit

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    The Comics Project: Synthesizing and Communicating Science with Comics
    Students, especially non-science majors, often see science as abstracted from their daily lives. Moreover, students often struggle to translate scientific concepts into everyday language in order...

    Keywords: communicating scienceScience & Societycomics

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    Tying it All Together: An Activity to Help Students Connect Course Experiences to Posted Learning Outcomes
    Instructors of undergraduate courses in Biology and other Science, Technology, Engineering, and Mathematics (STEM) disciplines face an ongoing challenge to foster higher-order thinking and learning...

    Keywords: metacognitionreflectiongoalsOutcomes

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    Integrating Primary Literature in a Lecture Course Using a Modified Version of the C.R.E.A.T.E. Approach
    Reforms in undergraduate science education place an increasing emphasis on teaching the skills of practicing scientists, such as reading and interpreting the primary research literature. Many...

    Keywords: primary literatureDiscussionModified JigsawPeer-based Learning

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    The Pipeline CURE: An Iterative Approach to Introduce All Students to Research Throughout a Biology Curriculum
    Participation in research provides personal and professional benefits for undergraduates. However, some students face institutional barriers that prevent their entry into research, particularly...

    Keywords: epigeneticsundergraduate researchmendelian inheritanceSelf-EfficacyCUREsnature of scienceResiliencecurriculum strategiesreprogramming

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