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    Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?
    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    Keywords: course based undergraduate research experiencesBLASTmolecular modelingSARS-CoV-2antibodyNextstrainiCn3DSequence alignmentStructure alignment

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    Diversifying and Humanizing Scientist Role Models Through Interviews and Constructing Slide Decks on Researchers’ Research and Life Experiences
    To maintain recruitment and retention, biology teachers face the challenge of finding relatable role models for their students. Our ever-increasing scientific knowledge has been facilitated by...

    Keywords: researchdiversityinclusionScientific ProcessRepresentationScientistRole Models

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    3-043-BallisticModeling-SpongeDart-ModelingScenario
    The goal of this project is for students to develop, analyze, and compare three different models for the flight of a sponge dart moving under the influences of gravity and air resistance.

    Keywords: projectile motionair resistanceballisticsdimensional analysisNewtonian mechanicssponge dartNerf gunNerf dartBuckingham's Theorem

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    1-028-SouthernSweetIcedTea-ModelingScenario
    We offer raw data collected from a webcam and a thermometer for evaluating the strength of steeping tea. We ask students to build a mathematical model using the data to predict how long the tea...

    Keywords: dataNewton's Law of Coolingteasweet tea

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    1-085-DrugBolus-ModelingScenario
    Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial...

    Keywords: concentrationsum of square errorsbolusdrugrate constantadminister

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    1-096-OP-AMP-Differentiator-ModelingScenario
    The output waveform (function) of a operational amplifier type of differentiator circuit is determined analytically from the first order governing ordinary differential equation and compared with...

    Keywords: simulationMeasurementfeedbackMultisimcircuitvoltageoperational amplifiervalidationSPICE

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    1-137-SheepGraze-ModelingScenario
    In this activity, students will apply graphical analysis (such as phase lines) to determine the long-term predictions of a differential equation model for pasture grass using two different formulas...

    Keywords: herbivoreplantphase linesbifurcationoverexploitationsheepgraze

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    1-160-HeartDeathRate-ModelingScenario
    Students simulate experience from a given data set which represents the heart death rate during the period 2000 - 2010 using several approaches to include exponential decay, difference equation,...

    Keywords: dataheart death rate

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    Machine Learning Meets Medicine with Jenessa Peterson
    Jenessa Peterson is a former teacher turned data scientist/engineer and Director of Learning Engineering at The Learning Agency. Her more recent work in data science has included building a...

    Keywords: data sciencemachine learningmedicine

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    3-071-WirelessTelegraphy-ModelingScenario
    This project has three parts, (1) done at home, (2) and (3) in class. In (1) we recall how to solve second order differential equations with constant coefficients and simple source functions. In...

    Keywords: bRLC circuitresonancebeatscurrentwireless telegraphyLC circuit

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    5-011-ModelingIbuprofren-ModelingScenario
    We consider modeling of data from a clinical experiment administered as oral doses of 400 mg ibuprofen, an analgesic pain reliever. Concentrations of ibuprofen in the serum/plasma of the subjects...

    Keywords: dataAICAkaike Information Criterionabsorptionsum of square errorscompartment modelibuprofendelay

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    5-012-LipoproteinModeling-ModelingScenario
    Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic...

    Keywords: wildlifelow-density-lipoproteintracercompartment modelcholesterolblood plasmabody tissue

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    5-015-RunnersSynchronize-ModelingScenario
    In this modeling scenario we practice finding and classifying equilibria of a one-variable differential equation. We do this in the context of a phase model which is often a simpler way of studying...

    Keywords: predatorAutonomous equationsoscillationcoupled oscillatorsynchronyrunnerpreyKuramato model

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    5-040-TunedMassDampers-PartII-ModelingScenario
    Studentsbuild mathematical models to mitigate dangerous swaying in structures using structural improvements called Tuned Mass Dampers (TMD). We model the motion of the original structure as a...

    Keywords: structureresistancespring-mass-dashpotearthquakevibrationcontroldampingtuned mass damperstiffnessreduction of vibration

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    9-030-WaterHammer-ModelingScenario
    We develop and apply a numerical algorithm that solves a system of two nonlinear partial differential equations (PDEs) that describes the time evolution of the water hammer phenomenon.

    Keywords: Stock and Flow modelhyperbolic equationsfinite differenceswater hammerhydrodynamicscompressibilitywave celerity

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    7-010-MultipleDoses-ModelingScenario
    Two multiple dose drug administration regimens are offered. A drug is to maintain a certain level (above a set minimum and below a set maximum) in the blood stream and one regimen involves bolus...

    Keywords: drug discoverystep functiondoseDiracdrug administrationinverse Laplace Transformintraveneousbolussteady drip

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    5-002-RelationshipDynamics-ModelingScenario
    The different possible dynamics of a two-person romantic relationship are modeled -- as a linear two dimensional system of equations -- and analyzed.

    Keywords: love affairRomeo and Juliet

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    3-105-FrequencyResponse-ModelingScenario
    We describe the frequency response to a second order differential equation with a driving function as the maximum steady state solution amplitude and perform some analyses in this regard.

    Keywords: transient dynamicscircuitspring massdriverfrequency responseamplitudesteady state

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    4-023-MysteryCircuit-ModelingScenario
    Students to build a system of differential equations which model a circuit. We give each student a unique input voltage frequency parameter and ask for system response (gain) to that input as a...

    Keywords: filterscircuitRLC circuitKirchhoffvoltagegaindriver

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    5-005-Dialysis-ModelingScenario
    We design a compartment model of a kidney dialysis machine and compare 3 and 9 compartments for the machine as well as determine the effect of change in one of the parameters in the model on the...

    Keywords: countercurrent multiplierkidneydialysisconcurrentcompartment

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