You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
    This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial...

    Keywords: LSDcorrelation coefficientcompartment modellysergic acid diethylamideperformancetest scoretissue concentration

    238

    views

    55

    downloads

    0

    comments

    0

    adaptations

    5-020-ParacetamolAbsorption-ModelingScenario
    We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and...

    Keywords: paracetamolanalgesicvegetariannon-vegetarian

    177

    views

    191

    downloads

    0

    comments

    0

    adaptations

    5-012-LipoproteinModeling-ModelingScenario
    Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic...

    Keywords: wildlifelow-density-lipoproteintracercompartment modelcholesterolblood plasmabody tissue

    430

    views

    184

    downloads

    0

    comments

    0

    adaptations

    1-132-DigoxinElimination-ModelingScenario
    We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study...

    Keywords: nullclinespharmacokineticsdigoxindrug eliminationtwo compartment

    298

    views

    407

    downloads

    0

    comments

    0

    adaptations

    1957-Axelrod_ Brady_Witkop_Evarts-The Distribution and Metabolism of Lysergic Acid Diethylamide
    The development of a specific and sensitive method for the estimation of LSD in biological materials has enabled us to study the tissue distribution, excretion, rate of biotransformation, and...

    Keywords: mathematical modeldataLSDMetabolismbloodstreamlysergic acid diethylamidedistribution

    176

    views

    58

    downloads

    0

    comments

    0

    adaptations

    3D breast cancer tissue reconstruction image files
    Database of image files for AIMS Resource: 3D breast cancer tissue reconstruction

    Keywords: Resources @ AIMS

    1025

    views

    132

    downloads

    0

    comments

    0

    adaptations

    2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.

    Keywords: kineticsSAScompartmentpharmacokinetics

    508

    views

    39

    downloads

    0

    comments

    0

    adaptations

    1996-D_Erdman-MM_Morelock-A Study of Kinetics
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.

    Keywords: simulationkineticsparameter estimationEnzymesubstratesavingscompartmentstomachbloodginseng

    160

    views

    43

    downloads

    0

    comments

    0

    adaptations

    Cell Division and Cancer Risk Data Point
    Cancer is typically attributed to hereditary and environmental factors, but these only explain a fraction of overall cancer risk. This activity explores a third factor.

    Keywords: Resources @ HHMI - BioInteractivecancerScientific ProcessStatistics and MathScientific Methodologybiology of cellscell growth and divisionHigh School

    2525

    views

    346

    downloads

    0

    comments

    1

    adaptations

    9-001-SkinBurnModelNumericalMethods-TechniqueNarrative
    The heat equation is an important partial differential equation (PDE) which describes the distribution of heat in a given region over time. Numerical methods play an important role in solving these.

    Keywords: Maternal-Fetal interfaceheat equationConservation of Energytheat fluxEuler's forward methodcentral differenceskin burnhyperthermiathermal conductivitylayers

    332

    views

    185

    downloads

    0

    comments

    0

    adaptations

    2014-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for...

    Keywords: metabolic syndromecompartment modelcholesterolhigh blood cholesterol

    125

    views

    57

    downloads

    0

    comments

    0

    adaptations

    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for...

    Keywords: metabolic syndromecholesterolhigh blood cholesterolcholesterol homeostasis

    103

    views

    68

    downloads

    0

    comments

    0

    adaptations

    Body Size Constraints in Xylem Feeding Insects: Allometric Relationships
    This module introduces body size constraints of xylem-feeding insects in the context of understanding allometric relationships. It is intended for an introductory biology audience.

    Keywords: allometryRatiosexponential equationslogarithmic equationsGenetics and Evolution

    939

    views

    175

    downloads

    0

    comments

    0

    adaptations

    1-130-AspirinAbsorption-ModelingScenario
    We model the amount of aspirin absorbed by the human body at a constant rate. This is a ``zero-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.

    Keywords: pharmacokineticsdrugaspirin

    220

    views

    156

    downloads

    0

    comments

    0

    adaptations

    1-131-CaffeineElimination-ModelingScenario
    We model the concentration of caffeine eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the...

    Keywords: caffeineeliminationpharmacokineticsdrug

    173

    views

    44

    downloads

    0

    comments

    0

    adaptations

    GEA Introductory lesson on RNA-Seq
    This RNA-Seq lesson uses the CyVerse VICE Platform and Jupyter notebooks to examine the expression of the leptin gene in samples from a mouse experimental design evaluating diet (high-fat vs....

    Keywords: data sciencebioinformaticsGenome BrowserRNAseqhigh throughput sequencingmRNAAlignmentNCBI Sequence Read Archive

    1489

    views

    694

    downloads

    0

    comments

    0

    adaptations

    Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix
    The extracellular matrix (ECM) provides structural support to cells, but also has key roles in mediating cell adhesion, cell signaling, and differentiation. While this topic is discussed in the...

    Keywords: Neural extracellular matrixPerineuronal netPrimary neuronal culture

    1181

    views

    279

    downloads

    0

    comments

    0

    adaptations

    2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
    Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.

    Keywords: liverwortsintraveneouspharmacokineticsethanolethanol infustionpharmacodynamictissue model

    114

    views

    36

    downloads

    0

    comments

    0

    adaptations

    Sizes, Scales and Specialization: Adapted to add scientific notation review
    This module explores how cell size and shape varies across cell types in the human body by having students calculate relative proportions of numbers in scientific notation. The adaptation has...

    Keywords: ExponentsRatiosScientific Notationcell typeqbccmanipulate equationsCellular and Molecular Biologyconverting unitschanging scales

    991

    views

    735

    downloads

    0

    comments

    0

    adaptations

    Sizes, Scales and Specialization: Using Relative Proportions and Scientific Notation to Highlight the Diversity of Cell Types
    This module explores how cell size and shape varies across cell types in the human body by having students calculate relative proportions of numbers in scientific notation.

    Keywords: ExponentsRatiosCellsqbccmanipulate equationsCellular and Molecular BiologyVisual Accommodationsconverting unitschanging scales

    5152

    views

    1277

    downloads

    0

    comments

    1

    adaptations

    Close

    Home

    Search