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    Build Multiomic and Visualization Skills in Bioscience Lecture
    This resource promotes inclusive learning by using all free platforms to extend the central dogma to an applied experience. Genomics is focused on with literature reviews that are performed to...

    Keywords: geneticsBiochemistryBiology and Biochemistry EduationProtein StructureBioinformatics and GenomicsFunctional GenomicstranscriptomicsproteomicsRNAseqClinical genomicsprotein structure modelingInclusive teaching3D protein structure /function analysisinclusive classrooms3D protein structuresinclusivegene

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    Maria vs Malaria
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria.

    Keywords: bioinformaticsmolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

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    BETTSI - Basic Evolutionary Tree-Thinking Skills Instrument
    A short, multiple choice diagnostic designed to provide instructors with a quick check on students’ understanding of and ability to read and interpret phylogenies.

    Keywords: EvolutionphylogeneticsTree thinking

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    2010-Shianga-EtAl-Computational model of the human glucose-insulin regulatory system
    A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced. The

    Keywords: glucose tolerance testsum of squared residualsmultiple shooting methodcost function

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    2008-Ribbing-EtAl-Mathematical models of diabetes progression
    Writing a good model for diabetes progression is difficult because the long time span of the disease makes experimental verification of modeling hypotheses extremely awkward. underlying the

    Keywords: physiologyclinical trialsdiabetesdiabetes progression

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    2003-Richard-Carson-Tracer kinetic modeling in PET
    The use of radiopharmaceuticals and the imaging of their biodistribution and kinetics with modern instrumentation are key components to successful developments in PET.

    Keywords: Metabolismtomographyradiopharmaceuticalspositron emission

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    3-063-FallingBuildingIce-ModelingScenario
    We model the fall of a piece of ice which is falling from a high building in New York City.

    Keywords: resistancefallinggravityiceterminal velocityskyscrapers

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    The Happy Blue Baby Hemoglobin
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    2003-Bohren-Dimensional analysis-falling bodies--fine art of not solving differential equations
    Dimensional analysis is a simple, physically transparent and intuitive method for obtaining approximate solutions to physics problems, especially in mechanics.

    Keywords: falling bodydimensional analysisdrag

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    COVID-19: On the way to a vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus origins, the molecular basis of the infection, the development and severity of symptoms, and treatment.

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Vaccine Development and Testing
    Scientists have the tools and knowledge to develop safe, effective vaccines, from trials to vials. This resource addresses the process by which vaccines are designed, tested and regulated. Key...

    Keywords: immunology educationvaccine literacyvaccine hesitancy

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    CURESUB Lecture 5 - OMICS
    s assistant professor in the department of medicine at Rutgers Robert Wood Johnson Medical School, Manisha Bajpai, PhD., led the Gastroenterology division’s clinical and translational research...
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    Studying disease with Dr. Ameeta Parekh of the FDA
    Ameeta Parekh, Ph.D. is the Senior Advisor for Scientific Collaborations in the Office of Translational Sciences for the FDA. She talked to us about the FDA's mission and purpose, an overview of...

    Keywords: diseasedrugsregulatory complianceFDA

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    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

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    Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website
    Cytochrome P450 (CYP) enzymes are important regulators of drug efficacy and toxicity. Genetic variation in CYP isoforms can impact how well patients respond to medications or experience unwanted...

    Keywords: toxicologyPharmacologydrug metabolismpharmacodynamicspharmacogenetics

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    Maria vs Malaria - AR Adaptation
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria. Students will be able to view selected molecular views from the...

    Keywords: bioinformaticsAugmented RealityLarge class sizemolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

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    Modeling Changes in Probability of Presence of Myotis lucifugus Due to White Nose Syndrome: An Introduction to Logistic Regression in R
    In this lesson, students will learn more about the wildlife disease known as white nose syndrome and how it affects certain bat species more than others. Students will learn about the important...

    Keywords: ecologyconservationRStudiobatslogistic regressionGLMWildlife DiseaseWhite nose syndromelittle brown batsmyotis lucifugus

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    Investigating Sexually Transmitted Disease (STD) Ecologies Using Geographic Information Systems (GIS) (Abstract) | TIEE
    Identifying, mapping and understanding the magnitude and the spatial prevalence of the Sexually Transmitted Diseases (STDs) such as chlamydia and gonorrhea diseases. Analyzing the spatial trends of...

    Keywords: Resources @ ESA - TIEEDisease ecologyfmnDIGhuman ecology and behaviorbacterial infectionsspatial and temporal spread of diseaseGeographic Information System (GIS)

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    2014-Enderling-Chaplain-Mathematical Modeling of Tumor Growth and Treatment
    Herein we describe fundamentals of mathematical modeling of tumor growth and tumor-host interactions, and summarize some of the seminal and most prominent approaches.

    Keywords: cancertumor modelingangiogenesistumor growthpatient care

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    2009-Marten-EtAl-Derivation and analysis of an ordinary differential equation for epilepsy dynamics
    In this paper we describe how an ordinary differential equation model of corticothalamic interactions may be obtained from a more general system of delay differential equations.

    Keywords: delayepilepsy dynamicsepilepsybistabilityseizure activity

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