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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to...

    Keywords: bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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    When tests disagree, how do I know if I have COVID-19?
    Students will learn about infectious disease and the immune response to infection by investigating different types of tests (PCR, antigen, and antibody tests) to detect the SARS-CoV-2 viral genetic...

    Keywords: geneticsVision and Changeintroductory biologyinfectious diseasemolecular biologycore competenciesRT-PCRviruscore conceptsnon-majors biologySARS-CoV-2antibodyAntigenImmunoReachmolecular DiagnosticsCOVID-19 transmission

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    Facilitating the implementation and adaptation of data-centric teaching resources by closing gaps in the Open Education Resource (OER) lifecycle
    Presentation on data-centric open educational resources given at the 2019 UBER-GRC

    Keywords: DIGdata-centric teaching

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    IPMpack: an R package for Integral Projection Models
    IPMpack is an R package (R Development Core Team 2013) that allows users to build and analyse Integral Projection Models.

    Keywords: RR-Forgeanimalbiostatisticscomparative analysisecologylongitudinal datamodel comparisonmodel estimationprojectionssurvivaltime seriestrajectoryIPMintegral projection modelsResources @ QUBES - Software

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    1-037-CommonColdSpread-ModelingScenario
    This modeling scenario guides students to simulate and investigate the spread of the common cold in a residence hall. An example floor plan is given, but the reader is encouraged to use a more...

    Keywords: diseasecommon coldresidence hall

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    Plants We Eat: Learning Form and Function from Fruits and Vegetables
    This high school or undergraduate lab consists of four activities that guide students through learning about plant parts from the fruits and vegetables with which they are already familiar....
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    Building Trees: Introducing evolutionary concepts by exploring Crassulaceae phylogeny and biogeography
    Teaching evolutionary theory is foundational for all biological sciences and a key aspect of overall science literacy. The conceptual framework for understanding evolution relies on thinking...

    Keywords: EvolutionphylogeneticsTree thinkingbiogeography

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    The Great Petunia Carnage of 2017: A Clicker Case Study Using Petunias to Describe the Effect of Genetic Modification on the Biochemistry of Flower Color and Phenotype in Plants
    In this single class period case study, students examine the difference between genotype and phenotype by studying the mechanisms by which commercially available petunias have been bred to have...

    Keywords: case studyGenetic ModificationsBiochemistry of Flower ColorGMO regulationsGenotype-Phenotype Connections

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    An Interactive Protocol for In-Classroom DNA Extraction
    Using commonly available materials, this tool allows students to extract DNA, exploring DNA chemistry and the principles of experimental design and execution. We take a “Choose Your Own...

    Keywords: geneticsDNAbiochemical structure and function

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    Discovering Cellular Respiration with Computational Modeling and Simulations
    Cellular respiration, a common topic among introductory and cellular biology curricula, is a complex biological process that exemplifies core biological concepts, including systems, pathways and...

    Keywords: Cellular MechanismsCellular RespirationFermentation

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    Serotonin in the Pocket: Non-covalent interactions and neurotransmitter binding
    This lesson introduces beginning biochemistry students to the concept of a biomolecule binding site, such as a neurotransmitter receptor site or an enzyme active site. A simple organic molecule,...

    Keywords: active sitebindingbinding sitehydrogen bondinghydrophobic effectionic interactionsnon-covalent forces

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    Go Extinct! An Award-Winning Evolution Game That Teaches Tree-Thinking as Students Pursue the Winning Strategy
    Evolutionary trees communicate both the diversity and unity of life, a central and important scientific concept, as highlighted by the Vision and Change undergraduate biology education movement....

    Keywords: phylogeneticsnatural historyBiodiversitycladogramCommon ancestorEvolutionary treeLand vertebratesMonophyletic cladeTetrapods

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    Engaging students in data exploration using digital biodiversity databases: BLUE Data Network
    Slides for BLUE presentation at 2020 BIOME Institute: Cultivating Scientific Curiosity

    Keywords: undergraduate researchnatural historyBiodiversitynatural history collectionsbiodiversity collectionsBLUEbiodiversity literacy

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    Interdisciplinary biology education: a holistic approach to an intractable problem
    Presentation on interdisciplinary biology education at the 2019 Great Lakes Bioinformatics Conference

    Keywords: quantitative biologyinterdisciplinarybioinformaticsbiology educationinterdisciplinary education

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    2015-G_Knott-Chemical Kinetics - Simple Binding F + G to and from B
    The study of this reaction, F + G goes to and from B, is common in chemistry and biochemistry. For example, F could be a hormone or drug and G the associated receptor sites.

    Keywords: bindingreactionchemical kineticsdeterministicBiochem Labsprobabilistickinetic reaction

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    2015-Beckmann-Sanchez-Cache Calculus-Modeling Caches through Differential Equations
    We present cache calculus, a technique that models cache behavior as a system of ordinary differential equations, letting standard calculus techniques find simple and accurate solutions of cache...

    Keywords: discretecachecache calculus

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    Will You Find This Humerus? Homology Lab
    Students will compare and contrast the morphology of vertebrate forelimbs, and will use this knowledge to draw conclusions about their common ancestor and descent with modification.

    Keywords: Evolutionbiologyidigbionatural history collections3D modelsVertebrate MorphologyoVerthomologous structuresWWISE

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    Cleaning Biodiversity Data: Excel
    Access and clean an open source polar bear dataset using Excel.

    Keywords: data in the classroombiodiversity informaticsData cleaning

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    Graphing grouped continuous data in R with swirl
    This lesson helps students know some of the options for how to graph grouped continuous data (such as those involved in doing a t-test or ANOVA) and how to choose the best option.

    Keywords: biostatisticsR programming languageSwirl

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    A Hands-on Introduction to Hidden Markov Models
    In this Lesson, we describe a classroom activity that demonstrates how a Hidden Markov Model (HMM) is applied to predict a eukaryotic gene, focusing on predicting one exon-intron boundary. This HMM...

    Keywords: transcriptionexonintronsplicing

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