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    Pharmacokinetics
    This Excel module explores how drugs are processed and absorbed in the human body.

    Keywords: drug metabolismpharmacokinetics

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    5-026-Evictions-ModelingScenario
    In this project, students develop two SIS models to study eviction trends in a population of non-homeowner households using an actual eviction rate. Students can calculate solutions, sketch the...

    Keywords: carrying capacitycompartmentevictionhomeownerSIS modelhomelessness

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    1-132-DigoxinElimination-ModelingScenario
    We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study...

    Keywords: nullclinespharmacokineticsdigoxindrug eliminationtwo compartment

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    2018-LA_Peletier-Ordinary Differential Equations in Pharmacodynamics
    Good mix of theory, application, solution technique in a number of areas of applications of differential equations. Develops qualitative behavior issues. Exercises, but not about models, more about...

    Keywords: compartment modelpharmacokineticspharmacodynamicsorbitsturnover

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    2018-David_Bourne-Pharmacokinetics – Source Material
    This is a rich source of pharmacokinetics modeling activities and data. These are syllabus notes with homework assignments listed.

    Keywords: boluspharmacokineticspharmacodynamicdrug distribution

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    2017-GR_Gustafson-Differential Equations Course Materials
    There are many applications from compartment and cascade analysis, recycling brine tank, home heating with multiple rooms, chemostat, microbes, heartbeats, lidocaine, nutrient flow in an aquarium,...

    Keywords: chemostatmicrobesbiomassforecastingtransfercompartmentpesticidesearthquaketankheatinglidocainebrineheartbeatsnutrient flowaquariumelectric networkscircuitsloggingbuildingcascade

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    2014-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for...

    Keywords: metabolic syndromecompartment modelcholesterolhigh blood cholesterol

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    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.

    Keywords: absorptioncompartmentbloodstreamplasmapharmacokineticsdrugpharmacodynamics

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    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.

    Keywords: absorptioncompartmentbloodstreamplasmapharmacokineticspharmacodynamicstherapeutic concentration rangedrug dispositiondrug response

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    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for...

    Keywords: metabolic syndromecholesterolhigh blood cholesterolcholesterol homeostasis

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    2014-Michael_Monagan-The Mortgage Payment Problem Approximating a Discrete Process with a Differential Equation
    In this article and a subsequent article I will give two non-standard examples that I've found helpful. The one presented here is a first order linear system. Second order systems and non-linear...

    Keywords: compartmentheatinghouse

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    2014-Hrydziuszko-EtAl-Mathematical Two-compartment Model of Human Cholesterol Transport
    We develop a two-compartment mathematical model to investigate cholesterol transport in the circulatory system and its de novo synthesis in the liver.

    Keywords: metabolic syndromecompartmentcholesteroltwo-compartment modelcholesterol transport

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    2012-Shargel-Yu-AccessPharmacy-Applied Biopharmaceutics and Pharmacokinetics
    Step by step formation of drug absorption models is shown with many good graphics of system and plots. Solutions are offered but no solution methods are shown.

    Keywords: Michaelis-MentenEnzymesubstratecompartmentpharmacokineticsrate constanturinary dataabsorption rate

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    2012-Arvind_Kumar_Misra-A simple mathematical model for the spread of two political parties
    In this paper, a non-linear mathematical model for the spread of two political parties has been proposed and analyzed by using epidemiological approach.

    Keywords: epidemiccompartmentpolitical parties

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    2011-Nakul-Chitnis-Introduction to Mathematical Epidemiology - Deterministic Compartmental Model
    Deterministic compartmental models form the simplest models in the mathematical study of infectious disease dynamics. They assume that a population is homogenous (all people are the same) and the...

    Keywords: sensitivitydiseaseinfectionthresholdcompartmentbifrucation

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    2011-Mandal-EtAl-Mathematical models of malaria
    The first aim of this article is to develop, starting from the basic models, a hierarchical structure of a range of deterministic models of different levels of complexity. The second is to...

    Keywords: epidemiologytransmissionhost-parasitemalariaRoss model

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    2009-Su-EtAl-Fitting Compartmental Models to Multiple Dose Pharmacokinetic Data using SAS
    In the case of a multiple dose study where subjects experience different dosing times, a superposition principle can be used to recursively account for each additional dose.

    Keywords: SASsuperpositionpharmacokineticscompartmental modelsmultiple dose

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    2009-Noakes-Sleigh-Mathematical models for assessing the role of airflow on the risk of airborne infection in hospital wards
    Understanding the risk of airborne transmission can provide important information for designing safe healthcare environments with an appropriate level of environmental control for mitigating risks.

    Keywords: infectioncompartmenthospitalventilationairbornesthochasticWells–Riley

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    2006-Ousmane_Mousa_Tessa-Mathematical model for control of measles by vaccination
    In this article, we use a compartmental mathematical model of the dynamics of measles spread within a population with variable size to provide this framework.

    Keywords: vaccinationcompartmentherd immunitymeaslesoptimal strategy

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    1-025-MixingItUp-ModelingScenario
    Students build three different models for levels of salt in a tank of water and at each stage the level of complexity increases with attention to nuances necessary for success.

    Keywords: compartmentsalttankmixing

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