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    COVID-19: Molecular Basis of Infection
    This case was written in Spring 2020 during the COVID-19 pandemic. It focuses on understanding the structure and interaction of the SARS-Cov-2 viral spike protein that facilitates infection in...

    Keywords: infectionvaccinemolecular visualization and analysisCOVID19PDBSARS-CoVMolecular Case Study

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    A Case of Severe Insulin Resistance
    This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to diabetes.

    Keywords: molecular visualization and analysisPDBMolecular Case Studyinsulin resistance

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    Evolution of Caffeine Biosynthesis Enzymes
    This case focuses on exploring why plants make secondary metabolites like caffeine and how the enzymes required for making caffeine evolved.

    Keywords: Evolutioncaffeinemolecular visualization and analysisenzymesPDBMolecular Case Study

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    Piwi Matters
    This case focuses on understanding structure and function relationships in Piwi, a protein that is critical for germline stem cell function and development of eggs in the fruit fly ovary.

    Keywords: Stem cellsmolecular visualization and analysis3D protein structure /function analysisPiwiPDBMolecular Case Study

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    Waking up Anna
    This case focuses on understanding the molecular basis of Anna's sleeping disorder and its treatment.

    Keywords: sleepmolecular visualization and analysisPDBMolecular Case StudyGABA

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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

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    That Vertebrate Ate What Exactly?
    During the course of this lesson, students will analyze CT scan data and observe bycatch (or an unknown discovery) captured during the scanning process of vertebrates.

    Keywords: EvolutionidigbioAP Biologynatural history collections3D modelsanatomy and physiology#NGSSVertebrate MorphologyCT scanoVert

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    Evidence of Evolution Homologous Structures
    Using CT (Computed Tomography) scans of vertebrate forelimbs, both as 3D models and as shapefiles, to enhance and illustrate the concepts of homologous structures, and the evolution of anatomical...

    Keywords: EvolutionidigbioZoology3D modelsanatomy and physiologyMiddle SchoolVertebrate MorphologyCT scanoVerthomologous structures

    1382

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    Diving into Deep Sea Data
    A module that combines NOAA's Okeanos Explorer and the iDigBio Portal to explore the deep sea!

    Keywords: Querying databasesremote sensingnatural history collectionsfishesscientific name5ESpeciesichthyologydeep sea

    1287

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    Louse Genetics, Genomics, and Gene Function...Oh My!
    In this module, students will be investigating a louse gene with an unknown function to determine if it might be important in the evolution of the louse ecomorphs.

    Keywords: parasitesgenomicsgene sequence analysisFunctional Genomics

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    Birds and Lice: Reciprocal Natural Selection
    This exercise investigates the form and function of lice and their relationship to their bird host.

    Keywords: BiodiversityparasitesbirdsCoevolutionnatural history collections

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    Louse and Human Coevolution
    This module examines the complicated co-evolution of Lice, Humans, and Great Apes

    Keywords: phylogeneticsBiodiversityparasitesCoevolutionhuman evolution

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    Movement: Nature's Flying Machines (Online)
    Adapted for online learning: In this lab, you will explore the physics of flight, the adaptations that make powered flight possible, and the evolution of powered flight in vertebrates and...

    Keywords: citizen sciencequantitative skillsDigital RepositoryFlight

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    Does Organelle Shape Matter? Exploring Cell Shape through the Allen Cell Explorer and High-content Microscopy Datasets
    The morphology and localization of structures inside the cell are often assumed to fit the ideal images found in biology textbooks. This interrupted case study using high-throughput microscopy data...
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    Chi-squared test of independence between two categorical variables
    In this lesson, students will have the opportunity to work through a chi-squared test of independence between two categorical variables.
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    Responses to Climate Change in California Chipmunks: Move, Adapt, or Die
    A series of three modules using data from natural history museum collections to examine responses to climate change in multiple chipmunk species. Elevation and morphological data, beginner skills...

    Keywords: statisticsmodelingmodulemorphologysummary statisticsmodulesclimate datamuseumsclimate changeundergraduate educationR programming languageprogrammingelevationnatural history museumsmammalssmall mammals community dynamicsmuseum collectionsVertebrate Morphologyopen educational resourceR programming environment

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    Introduction to Genome Annotation
    This exercise is an adaptation of the Annotation Lesson by Rosenwald et al. It introduces the use of bioinformatics tools to extract information from genome databases. It is a basic lesson on...

    Keywords: microbiologyGenome annotationBioinformatics EducationBioinformatics and Genomics

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    REMNet Tutorial, Excel Part 3: Organizing Your Microbiome Data 5.3.19
    Video on organizing microbiome using Excel from the Research Experiences in Microbiomes Network

    Keywords: ExcelVideoMicrobiology Educationmicrobiomesresearch in the classroomREMNeturban microbiomes

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    Teaching introductory bioinformatics with Jupyter notebook-based active learning
    Presentation on teaching introductory bioinformatics with Jupyter notebook-based active learning at the 2019 Great Lakes Bioinformatics Conference

    Keywords: biostatisticsstatistical analysisavian malariaSummer Workshop 2018

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