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    Using Bioinformatics to Understand Genetic Diseases: A Practical Guide
    This Practical Guide outlines a number of basic bioinformatics approaches that can be used to understand the molecular basis of genetic diseases.
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    Following the Data - PowerPoint Addition to Module
    This PowerPoint presentation guides instructors and students through the key background information for the module.
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    Investigating human impacts on stream ecology: locally and nationally
    How does nutrient pollution impact stream ecosystems locally and nationally?
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    Investigating the Ecology of Mosquitoes and Birds in Hawaii
    Examining biotic and abiotic environmental factors explain the historic, present, and future prevalence and range of avian malaria in Hawaii. The activity also asks how this affects local...

    Keywords: data analysisintroductory biologyInvasive SpeciesbirdsHawaii County

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    Using Undergraduate Molecular Biology Labs to Discover Targets of miRNAs in Humans
    In this lesson, we describe an easily adaptable lab module that can be used in existing undergraduate molecular biology lab courses to conduct authentic scientific research, published in CourseSource

    Keywords: molecular biologybioinformaticsNIBLSEgene regulationmicroRNAsgene expressionCourseSourcemiRNA

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    Using DNA Subway to Analyze Sequence Relationships
    This is a bioinformatics exercise using the DNA Subway Blue Line, a user-friendly pipeline of bioinformatics tools, to analyze a collection of mosquito DNA bar-code sequences.

    Keywords: phylogeneticsNIBLSEDNA BarcodingDNA sequenceBLASTmultiple sequence alignmentC1. Role of bioinformaticsC2. Computational conceptsC4. Bioinformatics toolsC5. Data retrievalC8. Data typesIncubated at NIBLSE

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    Using the IEDB to Predict Proteasomal Cleavage Events and T-cell Epitopes
    Research experiences provide a valuable view into the world of science and a great way to explore new fields and careers while developing critical thinking skills. The development and maintenance...

    Keywords: biologydatabaseImmunologydata sciencebioinformaticsBiotechnologyt-cellengineeringantibodyBioengineeringAntibody EngineeringlymphocytesProteinNetChopepitopeIEDBB-cellProteasomeProteasomal Cleavage

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    Distributions CURE- Exploring Species Distribution Changes and their Drivers
    This course-based undergraduate research experience (CURE) uses digitized natural history collections data to answer questions about species distributions and their drivers. This inclusive CURE can...

    Keywords: Evolutionecologyidigbiodata management#iNaturalistcourse based undergraduate research experienceshuman impactsspecies distributionscourse-based research experiences (CUREs)digitized natural history collectionsGBIFQGISBCEENETgeoreferencing

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    BSL-4: Authorized Personnel Only
    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    Keywords: infectious diseaseexperimental designbioinformaticsEbolaNIBLSECase It!PCRBLASTmultiple sequence alignmentPublished in National Center for Case Study Teaching in Sciencepolymerase chain reactionfebrile illnessvirusELISAenzyme linked immunosorbent assayfilovirusAfrica

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    Inquiry-based hypothesis testing using phylogenetic trees in MEGA
    A key learning objective in biology is applying bioinformatics tools to test a real-life question. These inquiry-based modules have students assemble and align data, and construct simple...

    Keywords: phylogeneticsbioinformaticsFASTANCBIBLASTmultiple sequence alignmentsequence similarityCourseSourceZika virusMEGAalcohol metabolism

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    A Critical Guide to the PDB
    This Critical Guide in the Introduction to Bioinformatics series provides a brief outline of the Protein Data Bank – the PDB – the world’s primary repository of biological macromolecular structures.

    Keywords: NIBLSEGOBLETInstructorResources

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    A Critical Guide to BLAST
    This Critical Guide in the Introduction to Bioinformatics series provides an overview of the BLAST similarity search tool, briefly examining the underlying algorithm and its rise to popularity.

    Keywords: NIBLSEBLASTGOBLETInstructorResources

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    Piwi Matters
    This case focuses on understanding structure and function relationships in Piwi, a protein that is critical for germline stem cell function and development of eggs in the fruit fly ovary.

    Keywords: Stem cellsmolecular visualization and analysis3D protein structure /function analysisPiwiPDBMolecular Case Study

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    Following the Data
    The video and exercise provides insight into how researchers are using digital data resources to investigate biodiversity in prairie fen wetlands.

    Keywords: data in the classroomprocess of sciencebiodiversity informatics

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    Communicating with Data: Infographic with Digital Data
    Working collaboratively in teams of 2-4 researchers, students engage in targeted projects to address critical information and research needs using digital biodiversity data.

    Keywords: databasesdata in the classroomundergraduate researchdigital collectionscourse-based research experiences (CUREs)biodiversity collections

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    Biodiversity research using digitized, internet-based natural history collections
    Collections based research is a critical tool for organismal biology and biodiversity research. Yet natural history collections have a complicated past. This multi-class module examines the...

    Keywords: natural historycollectionsdigital resourcesOERBiodiversitynatural history museumsdigital collectionsbirdsBiodiversity Collections Network (BCoN)BLUE

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    What is Science?
    This video has a philosophical focus and explores the nature of science. We’ll hear about how science is both a body of knowledge and a process. Peer review and confirmation bias will also be covered.

    Keywords: videosStudent misconceptionsScience Forwardscience basics

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    Painting turtles: an introduction to species distribution modeling in R
    This module uses R software to introduce students to the process of accessing databases and building species distribution models based on occurrence records.

    Keywords: RResources @ ESA - TIEEfmnDIGspecies distributionshabitat suitabilitycooperative learningjigsaw

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    A Growing Concern: Sustaining Soil Resources through Local Decision Making
    This module addresses this need by providing students the opportunity to examine the differences between intensively managed agricultural landscapes (e.g. grazelands, conventional tillage) and...

    Keywords: sustainabilityenvironmental sciencegeologysoil scienceResources @ InTeGrate

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    Applying phylogenetic tree building in MEGA X to forensic applications for identifying unknown specimens
    This exercise is designed to guide a learner through the construction of phylogenetic trees as a means of addressing research questions in forensic science such as the identification of previously...

    Keywords: taxonomyBioinformatics and GenomicsDNA Barcodinginvertebrate phylogeneticsforensic entomology

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