QUBES - Resources

Using an Interactive Game, Gutsy, to Examine the Impacts of Pathogens and Everyday Events on the Human Gut Microbiome

The human gut microbiome is often associated with ‘good bacteria’ in marketing campaigns for dietary supplements, probiotic drinks, and fermented foods. Yet, the dynamic and complex...

Keywords: bacteriaGamepathogenhealthmicrobiomediversity

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Teaching Thermal Physiology of Reptiles and Amphibians to Undergraduate Students

This module contains materials and activities for teaching undergraduate students about the thermal physiology of reptiles and amphibians. The module begins with an interactive lecture introducing...

Keywords: animalecologyconservationclimate changeHerpetologyUndergraduatephysiologyTemperature ChangeAmphibans and ReptilestemperatureMetabolismsnakesdigestive systemreptileslizardcrticial thermal maximumthermoregulation

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Using Collaborative Projects to Promote Active Learning of Microbial Skin Diseases and Their Impact on Everyday Lives

One of the most daunting aspects of introductory clinical microbiology is learning details about a vast number of different microbial diseases that can infect humans. Each of these diseases has...

Keywords: infectious diseasecollaborationpathogenesisTreatment of diseasesReal-life Microbiology

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Defining and Understanding Pathogenic Disease: An Engaging Activity that Connects Students' Lived Experiences with their Academic Studies

Contagious diseases are unavoidable realities of life. Thus, understanding pathogens and their respective diseases is important in many biological subfields including evolution, ecology, health...

Keywords: infectious diseasePathogenspathogenic disease

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A Simple Method for Predicting a Molecule's Biological Properties From Its Polarity

The distinction between very polar and less polar substances is a foundation of biochemistry, cell biology, and physiology; it surfaces in multiple concept inventories and elaborations of...

Keywords: Diffusionsolubilitycovalent bondshydrophilichydrophobicpartition coefficientplasma membranepolarity

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Three Research-Based Quantitative Reasoning Modules for Introductory Organismal Biology Laboratories

We have designed three laboratory modules for an introductory organismal biology course with an emphasis on quantitative reasoning and data analysis skills. Module 1 tests for dimorphism in...

Keywords: allometryplantsAnatomytranspirationdimorphisminvertebrate biologyarthropodsplatyhelminths

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Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab

Structure and function are correlated at all levels of biology. This topic is typically addressed early in an undergraduate class in general or molecular biology before students have gained much...

Keywords: Protein StructureproteaseEnzymechemical bondscatalysissolubility

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Doctor in the House: Improving Undergraduate Critical Thinking Skills Through Diagnosing Medical Case Studies

Students in undergraduate anatomy and physiology courses are not often exposed to clinical examples of homeostatic imbalances, particularly ones that provide an opportunity to diagnose a...

Keywords: medicinediagnosiscardiovasculardeductive reasoningdigestiveEndocrinehomeostatic imbalancehypothetico-deductive modelurinary

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Understanding Gastric Acid Secretion: An Active Learning Approach

The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the...

Keywords: diseasesignal transductionAcid SecretionAutonomic Nervous SystemEndocrineGastric PhysiologyGPCRHistology of Gastric Pit

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The Inside and Outside the Body

The Inside and Outside the Body activity helps students develop a conceptual understanding of anatomical barriers such as skin and mucus membranes that separate internal cells and fluids from the...

Keywords: structureAnatomybarriers

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The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups

Students have difficulty understanding synaptic integration in neural circuits, and how spatial and temporal summation combine in a target neuron to reach threshold. This Lesson uses small...

Keywords: neuron physiologyspatial summationsynaptic integrationtemporal summationthreshold

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Does it pose a threat? Investigating the impact of Bt corn on monarch butterflies

Aspiring scientists know that a hallmark of science is that experiments are repeatable and testable. However, students do not often get opportunities to explore the replicability of...

Keywords: ecologyCommunity EcologyBt cornGenetic modificationMonarch butterflies

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Examining the Physiology Behind the Symptoms of Lactose Intolerance

This is a set of extension questions for the HHMI short film The Making of the Fittest: Got Lactase? The Co-evolution of Genes Video Activity.

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Cystic Fibrosis Mechanism and Treatment

This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop...

Keywords: Resources @ HHMI - BioInteractiveBiochemistrymacromoleculesGenetic diseaseCell Structure & Function

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Water Movement through a Membrane: The Van't Hoff Equation

This module introduces the van't Hoff equation in the context of understanding the metabolic activity of the epithelial cells lining the stomach. It is intended for an introductory biology audience.

Keywords: AlgebraInequalitiesCellular Processes

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Using an Interactive Game, Gutsy, to Examine the Impacts of Pathogens and Everyday Events on the Human Gut Microbiome

Teaching Thermal Physiology of Reptiles and Amphibians to Undergraduate Students

Using Collaborative Projects to Promote Active Learning of Microbial Skin Diseases and Their Impact on Everyday Lives

Defining and Understanding Pathogenic Disease: An Engaging Activity that Connects Students' Lived Experiences with their Academic Studies

A Simple Method for Predicting a Molecule's Biological Properties From Its Polarity

Three Research-Based Quantitative Reasoning Modules for Introductory Organismal Biology Laboratories

Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab

Doctor in the House: Improving Undergraduate Critical Thinking Skills Through Diagnosing Medical Case Studies

Understanding Gastric Acid Secretion: An Active Learning Approach

The Inside and Outside the Body

The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups

Does it pose a threat? Investigating the impact of Bt corn on monarch butterflies

Examining the Physiology Behind the Symptoms of Lactose Intolerance

Cystic Fibrosis Mechanism and Treatment

Water Movement through a Membrane: The Van't Hoff Equation

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