You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    1-132-DigoxinElimination-ModelingScenario
    We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study...

    Keywords: nullclinespharmacokineticsdigoxindrug eliminationtwo compartment

    295

    views

    407

    downloads

    0

    comments

    0

    adaptations

    The Tentative Nature of Science
    This part focuses on the tentative nature of science

    Keywords: scienceCOVID19Tentative Nature

    291

    views

    238

    downloads

    0

    comments

    0

    adaptations

    6-005-InsectColonySurvivalOpt-ModelingScenario
    We present a system of nonlinear differential equations to model the control of energy flow into producing workers or reproducers in an insect colony, using a set of given parameters and a number...

    Keywords: optimizationOptimal Control Theoryinsect colonyoptimal controlnatural resourcesPointryagin's Maximum Principlecontrol variable

    360

    views

    186

    downloads

    0

    comments

    0

    adaptations

    2017-Justin_Krueger-Parameter Estimation Methods for Ordinary Differential Equation Models with Applications to Microbiology
    We demonstrate the feasibility of principal differential analysis using simulation studies and then apply the method to intestinal and vaginal microbiota data.

    Keywords: microbiologyLotka Volterrramicrobiota

    208

    views

    62

    downloads

    0

    comments

    0

    adaptations

    2017-Chávez-EtAl-Modeling and Analysis of Integrated Pest Control Strategies via Impulsive Differential Equations
    The paper is concerned with the development and numerical analysis of mathematical models used to describe complex biological systems in the framework of Integrated Pest Management (IPM).

    Keywords: bifurcationschaosimpulsive modellimit cycleshysteretic effectsperiod-doubling cascades

    211

    views

    72

    downloads

    0

    comments

    0

    adaptations

    2014-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for...

    Keywords: metabolic syndromecompartment modelcholesterolhigh blood cholesterol

    125

    views

    57

    downloads

    0

    comments

    0

    adaptations

    2016-Lewnard-Townsend-Climatic and evolutionary drivers of phase shifts in the plague epidemics of colonial India
    Our analysis shows that historical datasets can yield powerful insights into the transmission dynamics of reemerging disease agents with which we have limited contemporary experience to guide...

    Keywords: infectious diseasepVector-Borne Diseaselagueplague

    115

    views

    40

    downloads

    0

    comments

    0

    adaptations

    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric...

    Keywords: pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy

    110

    views

    72

    downloads

    0

    comments

    0

    adaptations

    2009-Schaffer-Bronnikova-Controlling malaria
    The present paper reviews potential control strategies from the viewpoint of mathematical epidemiology.

    Keywords: epidemiologymalariabifurcationmosquitotransgenic mosquitoes

    196

    views

    35

    downloads

    0

    comments

    0

    adaptations

    2009-Munz-EtAl-When Zombies Attack-Mathematical modelling of an Outbreak of Zombie Infection
    We introduce a basic model for zombie infection, determine equilibria and their stability, and illustrate the outcome with numerical solutions.

    Keywords: zombiesinfectionepidemicwater treatmentlatent infectionquarantineimpulsive eradication

    195

    views

    62

    downloads

    0

    comments

    0

    adaptations

    2006-Wilensky-Reisman-Thinking Like a Wolf a Sheep or a Firefly
    We describe a computation-based approach that enables students to investigate the connections between different biological levels using agent-based, embodied modeling tools.

    Keywords: simulationNetLogopredator-preyagent-basedwolffox

    235

    views

    58

    downloads

    0

    comments

    0

    adaptations

    2006-Loyd-Wodarz-Drug Resistance in Acute Viral Infections-Rhinovirus as a Case Study
    We develop an epidemiological model that can be used to address the spread of resistance at the population level, and a virus dynamics model that can be used to study the dynamics of virus over the...

    Keywords: stabilityresistancevirusdrugepidemic competitionimmune responserhinovirus

    114

    views

    42

    downloads

    0

    comments

    0

    adaptations

    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not...

    Keywords: sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search

    183

    views

    42

    downloads

    0

    comments

    0

    adaptations

    1989-R_Blickhan-Spring Mass Model For Running-Hopping
    A simple spring—mass model consisting of a massless spring attached to a point mass describes the interdependency of mechanical parameters characterizing running and hopping of humans as a function...

    Keywords: spring massjumpjumping

    123

    views

    51

    downloads

    0

    comments

    0

    adaptations

    1976-JG-Wagner-Computers in pharmacokinetics
    This is a seminal paper in pharmacokinetics in which the author introduces historic notions and approaches. As can be seen from the abstract there is a variety of material here.

    Keywords: kineticscomputerparametersPharmacologydrugspharmacokinetics

    280

    views

    42

    downloads

    0

    comments

    0

    adaptations

    2018-Robert_Phair-Differential_equation_methods_for_simulation_of_GFP_kinetics_in_non–steady_state_experiments
    Here, we derive new tracer kinetic analytical methods for non–steady state biological systems by constructing mechanistic nonlinear differential equation models of the underlying cell biological...

    Keywords: protein quality controlkineticsCellssteady statechemical kineticsfluouresencephotoactivationinytracellular

    256

    views

    39

    downloads

    0

    comments

    0

    adaptations

    2017-Thomas_Judson-The_Ordinary_Differential_Equations_Project
    This text is intended for a one-semester undergraduate course in ordinary differential equations. There are additional exercises or computer projects at the ends of many of the chapters.

    Keywords: projectsmathematical modeltextbooktechniquesfreeproofssageTheory

    210

    views

    81

    downloads

    0

    comments

    0

    adaptations

    2019-Stender_EtAl-Recovery_Of_Differential_Equations_From_Impulse_Response
    In this work, a recent method, which allows reconstructing differential equations from time series data, is extended for higher degrees of automation.

    Keywords: time seriesregressionresponseimpulseoscillationsignal processingsparse regressionsystem identification

    776

    views

    40

    downloads

    0

    comments

    0

    adaptations

    Venom Diversity & Evolution in Reptiles and Amphibians - An education module for university students
    This module contains information for a three part series introducing the venom system in reptiles and discussing it in an evolutionary context. In the first part venom and its ecological roles are...

    Keywords: geneticsEvolutionecologyHerpetologyAmphibans and ReptilesVenom

    1042

    views

    534

    downloads

    0

    comments

    0

    adaptations

    1-009-Bifurcation-TechniqueNarrative
    We lead students to investigate first-order differential equations that contain unknown parameters. Students discover what happens to the qualitative behavior of solutions to these equations as...

    Keywords: bifurcationqualitative behaviorbifurcation diagram

    309

    views

    116

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search