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    Connecting Viral Pandemics to Ecological Population Growth Models
    In this activity students use the HHMI Population Growth Models interactive to explore R0 for diseases and discuss the importance of connecting population ecology to current events like the...
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    Sickle Cell Disease and Natural Selection in Humans
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

    1951

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    Cystic Fibrosis Mechanism and Treatment
    This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymacromoleculesGenetic diseaseCell Structure & Function

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    6-045-CholeraTranmission-ModelingScenario
    During the project described here, the students will learn how to solve and address a practical problem such as cholera transmission using various mathematical tools.

    Keywords: infectious diseasecholeraendemicdisease-freetransmission ratewaterborne pathogen

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    Sickle Cell Disease Case Study
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

    2019

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    Social Distancing Simulation in NetLogo
    A NetLogo simulation that shows the effects of social distancing on the spread of infectious disease.
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    1-024-MalariaControl-ModelingScenario
    This project offers students a chance to make policy recommendations based on the analysis of models using both linear (exponential decay) and non-linear (logistic growth) differential equations.

    Keywords: population dynamicsmalariaPolicyDecision-makingEuler's methodpharmacokineticsmosquitoimproved Euler's methodHuen's methodUS Army

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    1-089-SpreadOfDisease-ModelingScenario
    In this project I want to use the algebra based concept “difference quotient” to solve differential equations models with the help of Excel. That means even students with only a College Algebra...

    Keywords: SIR modelProportionderivativedifference quotientSleeping Beautycontagious disease

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    Exploring the Application of Genetic Concepts to the Process of Disease in a Pathophysiology Course for Undergraduate Nursing Students
    Poster on incorporating genetics concepts related to human disease into nursing courses presented at the 2019 BioQUEST & QUBES Summer Workshop
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    2012-Tweedle-Smith-Mathematical model of Bieber Fever-The most infectious disease of our time
    We develop a mathematical model to describe the spread of Bieber Fever, whereby individuals can be susceptible, Bieber-infected or bored of Bieber.

    Keywords: infectious diseasediseaseinfectionmediaJustin BieberBieber feversymptomsboredreproductive ratio

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    2011-Nakul-Chitnis-Introduction to Mathematical Epidemiology - Deterministic Compartmental Model
    Deterministic compartmental models form the simplest models in the mathematical study of infectious disease dynamics. They assume that a population is homogenous (all people are the same) and the...

    Keywords: sensitivitydiseaseinfectionthresholdcompartmentbifrucation

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    2011-Gaff-Lenhart-Use of optimal control models to predict treatment time for managing tick-borne disease
    Tick-borne diseases have been on the rise recently, and correspondingly, there is an increased interest in implementing control measures to decrease the risk. Optimal control provides an ideal tool...

    Keywords: diseaseoptimal controlTICKtick modeehrlichiosisbang bang control

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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

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    4

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    2018-Nyanginja-Angwenyi-Musyoka-Orwa - Mathematical modeling of the effects of public health education on tungiasis
    In this paper, we formulate and study a mathematical model for the dynamics of jigger infestation incorporating public health education using systems of ordinary differential equations and...

    Keywords: diseaseendemicreproduction numbertungiasisjigger infestation

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    Ecology of Infectious Disease: Data Mining the National Notifiable Diseases Surveillance System (NNDSS) for Ecological Patterns
    How to use publicly available infection case data to teach ecology and evolution of human infectious diseases.

    Keywords: Evolutionecologyinfectious diseasehumansjigsawsmall group workEvolutionary medicinedata explorationCDCNNDSS

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    Sickle Cell Anemia using Nicholas’ Story
    The goal of this exercise is to introduce students to 3-D structures of biological molecules, visualize and manipulate them to understand their functions. The exercise also helps them see the...

    Keywords: Hemoglobinsickle cell diseaseMolecular Case Study

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    Mendelian Genetics, Probability, Pedigree, and Chi-Squared Statistics
    A lesson that requires students to work through a series of questions pertaining to the genetics of sickle cell disease and its relationship to malaria.

    Keywords: geneticsResources @ HHMI - BioInteractiveScientific ProcessStatistics and Mathmendelian inheritance

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    Science and Society: Integrating Historical Science Materials Into an Undergraduate Biology Course
    Vision and Change in Undergraduate Biology Education (American Association for the Advancement of Science, 2011) stresses the importance of fostering an understanding of the relationship between...

    Keywords: infectious diseasevaccinationbacteriavirusesantibiotics

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    2020-TeachingModule-SpreadOfCommonColdSimulation
    This simulation is meant to introduce the idea of a differential equation model and investigate the impact of heightened hygiene and decreased interactions on the spread of an infectious disease....

    Keywords: simulationmoduleinfectious diseasediseasespreadTeaching Modulespread of disease

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