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    5-011-ModelingIbuprofren-ModelingScenario
    We consider modeling of data from a clinical experiment administered as oral doses of 400 mg ibuprofen, an analgesic pain reliever. Concentrations of ibuprofen in the serum/plasma of the subjects...

    Keywords: dataAICAkaike Information Criterionabsorptionsum of square errorscompartment modelibuprofendelay

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    Opioid crisis: exploring the neurophysiology of opioid receptor signaling
    Using this dataset, we explore how opioids affect the electrical activity of neurons when exposed to different opioid receptor agonists and antagonists.

    Keywords: opioid epidemic

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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

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    Nicholas' Story
    This 3 part case on sickle cell disease focuses on visualizing and understanding the molecular basis of its cause, symptoms, complications, management, treatment, and possible cures.

    Keywords: Hemoglobinmolecular visualization and analysissickle cell diseasePDBMolecular Case Study

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    Cancer Genetics and an Interview with a Deaf Biomedical Researcher
    In this lesson, learners will learn about cancer genetics and understand and interpret graphs showing quantitative trait locus (QTL) data, survivor curve data, and other genetics data. Then,...

    Keywords: graph interpretationfmnDeaf EducationBioGraphIrepresentation in STEMBioGraphI graph InterpretationDeaf representation in STEM

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    1-109-EmployeeAttrition-ModelingScenario
    This scenario models the loss of employees and the employer's attempt to retain them through stock options. It most naturally is solved with a first-order linear decay model with two populations.

    Keywords: populationlinear growthdecayemployeeattrition

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    Fostering and Sustaining Interdisciplinary Faculty Communities Around Undergraduate Teaching: Insights from the QUBES Project
    Talk given as a part of the Symposium - Communities of Practice for Math Modeling Education at the SIAM 2018 Conference

    Keywords: SIAMQUBESfaculty communitiesResources @ MMHubResources @ SIAMEd 2018

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    Maternal transmission of microbiome
    Understanding the cascading effects of the transfer of maternal microbiome during a vaginal birth (vs. a c-section) to the well-being of a newborn.

    Keywords: microbiomehuman reproduction

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    Maria vs Malaria - AR Adaptation
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria. Students will be able to view selected molecular views from the...

    Keywords: bioinformaticsAugmented RealityLarge class sizemolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

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    2011-GA_Koch-Noble-Drugs in the Classroom Using Pharmacokinetics to Introduce Biomathematical Modeling
    By beginning with simple model involving the half-life of a drug, students take advantage of their mathematical abilities to explore the biology.

    Keywords: Biomathematicspharmacokinetics

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    5-020-ParacetamolAbsorption-ModelingScenario
    We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and...

    Keywords: paracetamolanalgesicvegetariannon-vegetarian

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    Using Immunocytochemistry and Fluorescence Microscopy Imaging to Explore the Mechanism of Action of Anti-Cancer Drugs on the Cell Cycle
    Understanding and visualizing the cell cycle and mitosis is an essential concept of cell biology. This multi-week lab module has students investigate the mechanism of action of anti-cancer drugs...

    Keywords: fluorescence microscopymitosisCell StructureCell ImagingImmunocytochemistryQuantitative microscopySTEM skills

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    Good Drug, Bad Practice: Tackling the Ivermectin Fiasco
    Throughout history, biomedical advancements have alleviated suffering worldwide and significantly advanced human well-being. As researchers and educators, we are well-familiar with the...

    Keywords: Peer reviewCOVID19fraudtherapeutic drugIvermectin

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    2019-Lorelei_Koss-SIR_Models_Differential_Equations_that_Support_The_Common_Good
    This article surveys how SIR models have been extended beyond investigations of biologically infectious diseases to other topics that contribute to social inequality and environmental concerns.

    Keywords: environmentSIRsocial justiceepidemiccommon good

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    6-017-OncolyticViruses-ModelingScenario
    Students explore oncolytic virotherapy using systems of differential equations and numerical simulations.

    Keywords: cancercancer-immune dynamicsimmune suppressor drugoncolytic virusvirotherapy

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    Cystic Fibrosis Mechanism and Treatment
    This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymacromoleculesGenetic diseaseCell Structure & Function

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    Pain Medication Treatment Modeling Project
    This classroom modeling project applies mathematical techniques to solve a problem related to drug dosage patterns. Suitable for high school or undergraduate students. Prerequisite: Calculus I.

    Keywords: Mathematical Biologycalculusexponential decayrecursionabsorptionelimination

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    When food gets scarce: how plant-pollinator interactions will shift under global change
    In this lesson, students review plant-pollinator interactions and global change concepts. Next, students interpret graphs of pollinator visitation data to Scarlet Gilia. Then, students view and...

    Keywords: mutualismsgraph interpretationCommunity Ecologyplantsfmnglobal changepollinatorsBioGraphIrepresentation in STEM

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    Defenses against predation: Interpreting graphs of predator behavior
    In this lesson, students discuss anti-predator defense mechanisms and the types of cues defenses provide to predators. Students then interpret graphs of behavior of arthropod predators when...

    Keywords: graph interpretationfmndata literacyinterspecific interactionsconsumptionBioGraphIrepresentation in STEMarthropodsaposematismphenotypic variationtortoise beetlecarton-nest antspraying mantisorb-weaving spider

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    Biodiversity Counts! Making sense of diversity metrics and graphs
    In this lesson students 1) become familiar with various graphs that are used to study diversity patterns within and across sites, 2) learn about some of the questions that can be addressed by...

    Keywords: graph interpretationfmnmetabarcodingbiodiversity literacyBioGraphIrepresentation in STEMalpha diversitybeta diversity

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