You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    5-022-ColdPill-ModelingScenario
    A model for the flow of a cold pill drug through the gastrointestinal compartment to the bloodstream compartment of a human subject is proposed. Students solve the system of differential equation...

    Keywords: ratesmedicinedrug discoverycompartmentcold pillgastrointestinalbloodstream

    355

    views

    206

    downloads

    0

    comments

    0

    adaptations

    7-010-MultipleDoses-ModelingScenario
    Two multiple dose drug administration regimens are offered. A drug is to maintain a certain level (above a set minimum and below a set maximum) in the blood stream and one regimen involves bolus...

    Keywords: drug discoverystep functiondoseDiracdrug administrationinverse Laplace Transformintraveneousbolussteady drip

    308

    views

    239

    downloads

    0

    comments

    0

    adaptations

    1-016-DogDrugs-ModelingScenario
    We offer a problem to determine the necessary drug administration in order to keep a dog sedated with specific information on half-life for an exponentially decaying presence of the drug in the body.

    Keywords: wild_dogsdrug discoveryhalf-lifepentobarbital sodiumanesthesia

    378

    views

    199

    downloads

    0

    comments

    0

    adaptations

    Drug Discovery through Ethnobotany
    In this lesson, students interpret graphs demonstrating synergy between antibiotics. Then, students view and reflect on an interview with biologist Dr. Cassandra Quave, whose research includes the...

    Keywords: graph interpretationfmndisabilityBioGraphIrepresentation in STEM

    88

    views

    12

    downloads

    0

    comments

    0

    adaptations

    A discussion of C-Path, regulation science, and recommended drug treatments with Nicholas King
    Nicholas King acts as the Scientific Program Manager for the Critical Path (C-Path) Institute’s Biomarker Program. He discusses the journey he has been on to arrive at his position, what the...

    Keywords: healthCollaborative researchdrug discovery

    718

    views

    141

    downloads

    0

    comments

    0

    adaptations

    Phenology publications
    Collection of modifications to TIEE phenology module from Data Discovery FMN

    Keywords: phenology

    797

    views

    185

    downloads

    0

    comments

    0

    adaptations

    2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
    This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.

    Keywords: concentrationphysiologydrugslag timeExtravascularPharamacokineticspeak time

    182

    views

    50

    downloads

    0

    comments

    0

    adaptations

    1-085-DrugBolus-ModelingScenario
    Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial...

    Keywords: concentrationsum of square errorsbolusdrugrate constantadminister

    310

    views

    228

    downloads

    0

    comments

    0

    adaptations

    Good Drug, Bad Practice: Tackling the Ivermectin Fiasco
    Throughout history, biomedical advancements have alleviated suffering worldwide and significantly advanced human well-being. As researchers and educators, we are well-familiar with the...

    Keywords: Peer reviewCOVID19fraudtherapeutic drugIvermectin

    2239

    views

    322

    downloads

    0

    comments

    0

    adaptations

    2012-Shargel-Yu-AccessPharmacy-Applied Biopharmaceutics and Pharmacokinetics
    Step by step formation of drug absorption models is shown with many good graphics of system and plots. Solutions are offered but no solution methods are shown.

    Keywords: Michaelis-MentenEnzymesubstratecompartmentpharmacokineticsrate constanturinary dataabsorption rate

    103

    views

    38

    downloads

    0

    comments

    0

    adaptations

    1-080-DrugAdministration-ModelingScenario
    A simple drug administration situation is modeled with only two observations.

    Keywords: decaybloodstreamdrugrate constantadminister

    231

    views

    114

    downloads

    0

    comments

    0

    adaptations

    Assessing in vivo Antimicrobial Activity Through the Analysis of Galleria mellonella Kaplan-Meier Plots
    Antimicrobials and their use in the treatment of bacterial infections are a fundamental lesson in all microbiology courses. Typically, cultivation-based methods are used to teach students about...

    Keywords: Antimicrobial TestingAntimicrobialsInvertebrate animal models

    2092

    views

    288

    downloads

    0

    comments

    0

    adaptations

    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.

    Keywords: absorptioncompartmentbloodstreamplasmapharmacokineticspharmacodynamicstherapeutic concentration rangedrug dispositiondrug response

    140

    views

    80

    downloads

    0

    comments

    0

    adaptations

    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics...

    Keywords: longitudinal dataAIDSantiretroviral drug therapyBayesian nonlinear mixed-effectstime-varying drug efficacyHIV dynamics

    142

    views

    47

    downloads

    0

    comments

    0

    adaptations

    2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
    The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important...

    Keywords: paracetamolpharmacokineticsstomachsmall intestinesulfapyridine

    143

    views

    46

    downloads

    0

    comments

    0

    adaptations

    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.

    Keywords: absorptioncompartmentbloodstreamplasmapharmacokineticsdrugpharmacodynamics

    133

    views

    56

    downloads

    0

    comments

    0

    adaptations

    Getting Started: Drug Treatment Calculations
    This assignment will help teach students...

    Keywords: experimentMicropipettingcalculationsdrug calculation

    10

    views

    6

    downloads

    0

    comments

    0

    adaptations

    Mock Drug Activity Enhances Student Learning About the Challenges of HIV/AIDS Therapy
    While traditional didactic coursework is important for learning about the scientific aspects of HIV/AIDS, it is difficult to convey social aspects of the epidemic. Due to effective drug therapies,...

    Keywords: drug resistanceRetrovirusViral replication

    1237

    views

    167

    downloads

    0

    comments

    0

    adaptations

    1-131-CaffeineElimination-ModelingScenario
    We model the concentration of caffeine eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the...

    Keywords: caffeineeliminationpharmacokineticsdrug

    334

    views

    123

    downloads

    0

    comments

    0

    adaptations

    1999-Peter_Deuflhard-Differential Equations in Technology and Medicine
    It deals with a variety of challenging real life problems selected from clinical cancer therapy, communication technology, polymer production, and pharmaceutical drug design.

    Keywords: cancerdesigntumordrugpolymertherapy

    152

    views

    48

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search