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    Effect of the Intestinal Protein Snakeskin on the Lifespan of Fruit Flies: A Kaplan-Meier Survival Analysissource Draft (1)
    In this activity, students perform the Kaplan-Meier survival analysis on raw data obtained from an experiment that explores the effect of overexpressing the Snakeskin (Ssk) protein on the lifespan...

    Keywords: graphingBiochemistryhypothesis testingcalculus and biologyapproximating areas under curvesqbccCellular and Molecular BiologyCreate graphsInterpret graphsSolving Equations and Inequalitiesinterpret tablesConcepts in Statisticsusing statisticschi-square analysissurvival analysis

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    Evaluating the potential for immune escape: how likely is an antibody to protect against a specific SARS-CoV-2 variant?
    Commercial antibodies to the SARS-CoV-2 spike protein have been successfully used to treat people with COVID-19. Unfortunately, as the SARS-CoV-2 virus evolves, new variants have appeared that can...

    Keywords: course based undergraduate research experiencesBLASTmolecular modelingSARS-CoV-2antibodyNextstrainiCn3DSequence alignmentStructure alignment

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    Understanding the Importance of Microtubules in Normal Cell Division: Chemotherapy Connection
    In introductory courses, students learn about microtubules as important structures but may not engage in a hands-on experience to localize microtubules themselves or to learn about their connection...

    Keywords: cancerCell DivisionimmunofluorescenceMicrotubulesAntibodies

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    A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics
    Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need...

    Keywords: epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

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    Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment
    Important learning outcomes for biology students include the ability to develop experiments as well as pull together concepts across their coursework. The field of developmental biology, especially...

    Keywords: toxicologymorphogenesisorganogenesis

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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently...

    Keywords: modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

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    From Dirt to Streptomyces DNA
    The purpose of this semester-long Lesson is to give students an authentic, course-based undergraduate research experience during which they learn basic and advanced microbiological and molecular...

    Keywords: MetabolismAntibiotic productionrRNA genesSecondary metabolitesStreptomyces

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    A 360˚ View of COVID-19
    In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new...

    Keywords: geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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    2007-Mogen_Steffensen-Differential Equations in Finance and Life Insurance
    The mathematics of finance and the mathematics of life insurance were always intersecting. Life insurance contracts specify an exchange of streams of payments between the insurance company and the...

    Keywords: financedisabilitylife insurancemortalityinsuraneThiele’s equationBlack-Scholes equation

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    Distributions CURE- Exploring Species Distribution Changes and their Drivers
    This course-based undergraduate research experience (CURE) uses digitized natural history collections data to answer questions about species distributions and their drivers. This inclusive CURE can...

    Keywords: Evolutionecologyidigbiodata management#iNaturalistcourse based undergraduate research experienceshuman impactsspecies distributionscourse-based research experiences (CUREs)digitized natural history collectionsGBIFQGISBCEENETgeoreferencing

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    Using Grassy Narrows in a Live Classroom with Clicker Questions and Interactive Histogram: Sampling Distributions, Probability, and Hypothesis Testing
    Students are introduced to concepts of sampling distributions, p-values, and hypothesis testing. Using both simulated and real data for methylmercury level in fish populations, students will...

    Keywords: statisticsmathematicsbiostatisticsecologybiologygraphingp-valuest-testshypothesis testingin-class activityZoologymercury biogeochemistrybiostatistics - generalfish populationqbccBiogeochemical cyclesInterpret graphsConcepts in StatisticsElementary Hypothesis TestingMethylmercurydamsBioaccumulationtraditional dietsmercurymercury poisoningnative peopleindigenous populationCanadahydroelectricexplaining statisticsusing statisticsMake probability calculations

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    Island biogeography, spatial ecology, and macroinvertebrate species diversity in Richmond’s rock pools
    Students investigate questions of community ecology and biogeography using data from an urban rock pool ecosystem. Using ArcGIS 10, students learn to create effective maps, calculate landscape...

    Keywords: aquatic macroinvertebratesCommunity Ecologyspecies diversityGeographic Information System (GIS)spatial analysisJames River

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    The nose knows: How tri-trophic interactions and natural history shape bird foraging behavior
    Students investigate the role of olfaction and infochemicals on bird foraging behavior through three different quantitative modules. In this module students create graphs, generate statistics, draw...

    Keywords: Resources @ ESA - TIEEforagingfmnbehavioral ecologyDIGtrophic cascadesAntarctic foodd webs

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    Introducing PHAGES Students to Primary Literature
    The ‘Introducing PHAGES Students to Primary Literature’ set of teaching resources offers faculty 2 distinct sets of teaching resources for introducing students to scientific literature in the...
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    Understanding Gastric Acid Secretion: An Active Learning Approach
    The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the...

    Keywords: diseasesignal transductionAcid SecretionAutonomic Nervous SystemEndocrineGastric PhysiologyGPCRHistology of Gastric Pit

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    Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study
    Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut microbiomes...

    Keywords: Vision and Changeecologyintroductory biologyImmunologymicrobiologydietanimal behaviormicrobiomecore conceptscoyotesBraingut-brain axisImmunoReachcytokinedysbiosis

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    Using the Project EDDIE Sustainability Metrics module in Exploring Earth
    Students use GapMinder, an interactive data exploration and visualization tool, to assess human impact on Earth systems. Using the impact = population x affluence x technology (IPAT) framework...

    Keywords: sustainabilityProject EDDIE

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    The ml4bio Workshop: Machine Learning Literacy for Biologists
    Presentation on machine learning literacy for biologists at the 2019 Great Lakes Bioinformatics Conference

    Keywords: bioinformaticsmachine learning

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    Coevolution or not? Crossbills, squirrels and pinecones
    This case reinforces the concept of coevolution as a reciprocal change in genetic structure between or among two or more populations, by having students analyze and interpret data, build a...

    Keywords: fitnessCoevolutionCo-adaptation

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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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