You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    2008-Ribbing-EtAl-Mathematical models of diabetes progression
    Writing a good model for diabetes progression is difficult because the long time span of the disease makes experimental verification of modeling hypotheses extremely awkward. underlying the

    Keywords: physiologyclinical trialsdiabetesdiabetes progression

    122

    views

    38

    downloads

    0

    comments

    0

    adaptations

    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics...

    Keywords: longitudinal dataAIDSantiretroviral drug therapyBayesian nonlinear mixed-effectstime-varying drug efficacyHIV dynamics

    106

    views

    30

    downloads

    0

    comments

    0

    adaptations

    Engaging Students in Pharmacogenetics: Patient Case Studies Using the PharmGKB Website
    Cytochrome P450 (CYP) enzymes are important regulators of drug efficacy and toxicity. Genetic variation in CYP isoforms can impact how well patients respond to medications or experience unwanted...

    Keywords: toxicologyPharmacologydrug metabolismpharmacodynamicspharmacogenetics

    1636

    views

    295

    downloads

    0

    comments

    0

    adaptations

    2007-Exben_Friis-Jensen-Modeling and Simulation of Glucose-Insulin Metabolism
    In this thesis one of the models of diabetes, Bergman’s minimal model is described trough derivation and simulations.

    Keywords: Metabolisminsulin resistanceglucosePID controllerintolerance

    93

    views

    44

    downloads

    0

    comments

    0

    adaptations

    2006-Loyd-Wodarz-Drug Resistance in Acute Viral Infections-Rhinovirus as a Case Study
    We develop an epidemiological model that can be used to address the spread of resistance at the population level, and a virus dynamics model that can be used to study the dynamics of virus over the...

    Keywords: stabilityresistancevirusdrugepidemic competitionimmune responserhinovirus

    107

    views

    42

    downloads

    0

    comments

    0

    adaptations

    2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
    The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important...

    Keywords: paracetamolpharmacokineticsstomachsmall intestinesulfapyridine

    110

    views

    37

    downloads

    0

    comments

    0

    adaptations

    2002-Nelson-Perelson-Mathematical analysis of delay differential equations models of HIV-1 infection
    We develop and analyze a set of models that include intracellular delays, combination antiretroviral therapy, and the dynamics of both infected and uninfected T cells.

    Keywords: infectionHIVT cells

    149

    views

    43

    downloads

    0

    comments

    0

    adaptations

    2002-Chai-Optimal initial angle to fire a projectile
    Assume a projectile is fired without air resistance and lands at a height y above its initial vertical position. What is the optimal initial angle of firing to maximize the horizontal distance...

    Keywords: optimizationprojectile motionlaunch angle

    97

    views

    39

    downloads

    0

    comments

    0

    adaptations

    2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.

    Keywords: kineticsSAScompartmentpharmacokinetics

    387

    views

    35

    downloads

    0

    comments

    0

    adaptations

    1999-Meade-Struthers-Differential Equations in the New Millennium-The Parachute Problem
    The parachute problem will be used to illustrate several essential features of the improved courses. In particular, it will be seen that the traditional version of the parachute problem is not very...

    Keywords: resistancefree fallparachutejumpskydiving

    104

    views

    42

    downloads

    0

    comments

    0

    adaptations

    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not...

    Keywords: sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search

    178

    views

    40

    downloads

    0

    comments

    0

    adaptations

    1987-MS_Greenwood-Using videotapes to study underdamped motion of a pendulum
    Using a video camera to study the effects of air resistance acting on pendulum bob, ping-pong ball, styrofoam spheres, and brass spheres.

    Keywords: Videoresistancependulumping-pong ballstyrofoam ballbrass ball

    99

    views

    36

    downloads

    0

    comments

    0

    adaptations

    1994-Roland_Minton-A Progression of Projectiles-Examples from Sports
    There is a progression of complexity and issues in projectile motion modeling from no resistance, to resistance proportional to velocity, then to velocity squared,

    Keywords: sportsresistanceprojectilebaseballdraglinear resistancequadratic resistancetennis

    108

    views

    40

    downloads

    0

    comments

    0

    adaptations

    1994-T_Gruszka-A Balloon Experiment in the Classroom
    The following experiment involves a balloon, a stopwatch, and a measurement device such as a meter stick,

    Keywords: resistancefalling bodydragballoon

    79

    views

    39

    downloads

    0

    comments

    0

    adaptations

    1999-Peter_Deuflhard-Differential Equations in Technology and Medicine
    It deals with a variety of challenging real life problems selected from clinical cancer therapy, communication technology, polymer production, and pharmaceutical drug design.

    Keywords: cancerdesigntumordrugpolymertherapy

    123

    views

    39

    downloads

    0

    comments

    0

    adaptations

    1996-D_Erdman-MM_Morelock-A Study of Kinetics
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.

    Keywords: simulationkineticsparameter estimationEnzymesubstratesavingscompartmentstomachbloodginseng

    154

    views

    41

    downloads

    0

    comments

    0

    adaptations

    1994-S_S_Everingham-C_Peter_Rydell-Modeling the Demand for Cocaine
    This is a report prepared for the Office of National Drug Control Policy of the United States Army by the Rand Corporation. The report contains lots of data and builds a two compartment difference...

    Keywords: drugstwo compartmentcocainedemand

    86

    views

    36

    downloads

    0

    comments

    0

    adaptations

    More information about the Discovery – Doing Science Biology Education Conference
    2023 Conference Theme - Variants in Biology Education: What can we learn from pandemics?

    Keywords: LDC2023

    230

    views

    146

    downloads

    0

    comments

    0

    adaptations

    1971-Boyes-Scott-Jebson-Godman-Julian-Lidocaine in Man
    Plasma levels of lidocaine were measured in 5 normal male volunteers following both intravenous and oral administration of the drug.

    Keywords: pPharmacologypharmacokineticslidocaine

    123

    views

    39

    downloads

    0

    comments

    0

    adaptations

    1980-Peastrel-Lynch-Armenti-Terminal velocity of a shuttlecock in vertical fall
    We have performed a straightforward vertical fall experiment for a case where the effects of air resistance are important and directly measurable.

    Keywords: fallingterminal velocityshuttlecockvertical fall

    172

    views

    41

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search