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    3-095-ShotInWater-ModelingScenario
    This project uses Newton's Second Law of Motion in conjunction with a quadratic model for the resistance experienced by a bullet moving through water to analyze a classic action movie scene.

    Keywords: projectile motionterminal velocityprojectilewater resistancereduction of orderfrictionair resistance

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    Mol* Adaptation: Case of Severe Insulin Resistance
    This is an adaptation using Mol* on the original case written. This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to...

    Keywords: molecular visualization and analysisPDBMolecular Case Studyinsulin resistanceMol*MolStar

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    A Case of Severe Insulin Resistance
    This case focuses on understanding how a mutation in a cell signalling protein (a kinase) can prevent insulin function and lead to diabetes.

    Keywords: molecular visualization and analysisPDBMolecular Case Studyinsulin resistance

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    3-033-S-TimeUpTimeDown-ModelingScenario
    We seek to compare for the time a projectile takes to go vertically up with the time it takes to return to its starting position.

    Keywords: projectile motionapexvertical motion

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    1987-MS_Greenwood-Using videotapes to study underdamped motion of a pendulum
    Using a video camera to study the effects of air resistance acting on pendulum bob, ping-pong ball, styrofoam spheres, and brass spheres.

    Keywords: Videoresistancependulumping-pong ballstyrofoam ballbrass ball

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    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not...

    Keywords: sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search

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    1971-Boyes-Scott-Jebson-Godman-Julian-Lidocaine in Man
    Plasma levels of lidocaine were measured in 5 normal male volunteers following both intravenous and oral administration of the drug.

    Keywords: pPharmacologypharmacokineticslidocaine

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    A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics
    Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need...

    Keywords: epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

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    2017-Ole_Witt-Hansen-Examples Of Differential Equations In Physics
    This is an article from the author’s homepage. The work contains fundamental and basic background and derivation of the differential equation models for a number of phenomena.

    Keywords: projectileair resistancefree falldragharmonic oscillation

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    2014-Groetsch-Yost-Vertical Projection in a Resisting Medium - Revelations on Observations of Mersenne
    This article, inspired by a 17th-century woodcut, validates empirical observations of Marin Mersenne (1588–1648) on timing of vertically-launched projectiles for a general mathematical model of...

    Keywords: resistanceprojectile

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    1-145-FastPitch-ModelingScenario
    We consider the problem of comparing pitch velocities using measurement methods in different eras of baseball.

    Keywords: Measurementresistanceair resistancebaseballpitcherfast

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    1-077-RLMSimSeriesCircuit-ModelingScenario
    In this validation setup, the first order linear ordinary differential equation governing a small signal RL series AC circuit is solved analytically and the results are compared with the data...

    Keywords: MeasurementcircuitvoltagecurrentvalidationSPICERL circuitMultilsim

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    3-015-StyrofoamBallFall-ModelingScenario
    We are given data on a falling Styrofoam ball and we seek to model this motion.

    Keywords: footballresistancegravityfalling bodysum of square errorsNewton's Second Law of Motionsum of forcesstyrofoam

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    3-017-StackedCoffeeFiltersFalling-ModelingScenario
    Data on free falling 2, 4, 6, and 8 stacked coffee filters is offered. Students form a model using a resistance term proportional to velocity, velocity squared, or velocity to some general power....

    Keywords: dataresistancefalling bodycoffee filterstacked

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    Maria vs Malaria
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria.

    Keywords: bioinformaticsmolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

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    2015-G_Knott-Chemical Kinetics - Simple Binding F + G to and from B
    The study of this reaction, F + G goes to and from B, is common in chemistry and biochemistry. For example, F could be a hormone or drug and G the associated receptor sites.

    Keywords: bindingreactionchemical kineticsdeterministicBiochem Labsprobabilistickinetic reaction

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    1994-S_S_Everingham-C_Peter_Rydell-Modeling the Demand for Cocaine
    This is a report prepared for the Office of National Drug Control Policy of the United States Army by the Rand Corporation. The report contains lots of data and builds a two compartment difference...

    Keywords: drugstwo compartmentcocainedemand

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    1964-Aghajanian-Bing-Persistence Of LSD In Plasma In Human Subjects
    Two micrograms per kilogram of LSD-25 was administered intravenously to five normal human subjects. The concentration of[ drug in plasma was determined serially over the subsequent 8 hours. We...

    Keywords: LSDscoreplasmalysergic acid diethylamidehuman subjuects

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    Studying disease with Dr. Ameeta Parekh of the FDA
    Ameeta Parekh, Ph.D. is the Senior Advisor for Scientific Collaborations in the Office of Translational Sciences for the FDA. She talked to us about the FDA's mission and purpose, an overview of...

    Keywords: diseasedrugsregulatory complianceFDA

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    A discussion of C-Path, regulation science, and recommended drug treatments with Nicholas King
    Nicholas King acts as the Scientific Program Manager for the Critical Path (C-Path) Institute’s Biomarker Program. He discusses the journey he has been on to arrive at his position, what the...

    Keywords: healthCollaborative researchdrug discovery

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