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    3-010-EnergyInSpringMassSystem-ModlingScenario
    As a way to synthesize the effects of damping and forcing terms, this activity is meant to encourage students to explore how different forcing terms will change the total energy in a mass-spring...

    Keywords: energymass-spring systemkinetic energypotential energytotal energy

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    3-067-RLCSeriesCircuit-ModelingScenario
    In this validation-oriented setup, the second order linear ordinary differential governing equation of a small signal RLC series AC circuit is solved analytically, and the results are compared with...

    Keywords: resistanceMultisimcircuitRLC circuitinductancecapacitancecimulationgoverning equation

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    3-073-EarthQuakePartII-ModelingScenario
    Your goal here is to determine how much friction/damping should be designed into a building to keep the roof from moving too far (which would result in the entire building collapsing) when it...

    Keywords: earthquakevibrationdampingamplitudespring-mass systemsteady-state solutionunderdamped

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    3-085-SimplePendulum-ModelingScenario
    Thestudent is asked to derive and solve a differential equation that gives the position (angle

    Keywords: Newton's Second Law of Motionpendulumkinetic energypotential energyConservation of Energytinitial conditionssmall angle approximationTaylor polynomialpercent error

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    3-092-WirelessPower-ModelingScenario
    We present an engineering application (wireless power transmission) modelled by a coupled system of two linear second-order differential equations with constant coefficients. One equation is...

    Keywords: DESMOSwireless power transmissionelectric circuitsKirchhoff's Voltage Law

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    7-020-ThermometerInVaryingTempStream-ModelingScenario
    We present a first order differential equation model for the temperature of a mercury thermometer which is sitting in a stream of water whose temperature oscillates. We suggest a solving strategy...

    Keywords: temperaturesteady statethermometerheat exchangetransfer functionphase lagInvers Laplace Transform

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    9-020-HeatDiffusion-ModelingScenario
    This project guides students through experimental, analytical, and numerical techniques for understanding the heat (diffusion) equation with nonhomogeneous boundary conditions. In particular,...

    Keywords: laboratoryDiffusionheat

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    3-069-HeatInBar-ModelingScenario
    The temperature distribution along a uniform slender bar due to conduction and convection is investigated through experimental, analytical, and numerical approaches.

    Keywords: heat transferexperimentconductionconvectionboundary conditionsfinite volume method

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    5-040-TunedMassDamper-Part-I-Modeling Scenario
    We offer an opportunity to build mathematical models to mitigate dangerous displacements in structures using structural improvements called Tuned Mass Dampers. We model the motion of the original...

    Keywords: structurespring-mass-dashpotspring massearthquakevibrationtuned mass tunerrestoring forcecontroldampe

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    Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students...

    Keywords: gene regulationtranscriptiongene expressioncentral dogmarepressoralternative splicingmRNA processingActivatorTranscription factors

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    A Classroom Intervention to Reduce Confirmation Bias
    STEM students are often unable to recognize cognitive bias in their own disciplines, and simply describing cognitive bias to students has shown to be insufficient to improve critical thinking....

    Keywords: biasprocess of sciencemetacognitionConfirmation BiasCognitive Bias

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    Teaching Advanced Concepts in Regulation of the Lac Operon With Modeling and Simulation
    Success in biochemistry and other life science courses requires that students understand important biological concepts. One of these concepts is how gene regulation ensures that homeostasis is...

    Keywords: gene regulationinducible operonProkaryotic cellPhosphoenolpyruvate transferase system (PTS)

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    Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis
    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education,...

    Keywords: transcriptioncentral dogmatranslationsequence analysisDNA replicationgenetic variants

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    Using Bioinformatics and Molecular Visualization to Develop Student Hypotheses in a Malate Dehydrogenase Oriented CURE
    Developing student creativity and ability to develop a testable hypothesis represents a significant challenge in most laboratory courses. This lesson demonstrates how students use facets of...

    Keywords: bioinformaticsNoncovalent InteractionsEnzyme CatalysisProtein Structure/function

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    A 360˚ View of COVID-19
    In March 2020, institutions underwent a massive transition to distance learning as a result of the COVID-19 pandemic. With so little time to devise new materials to maximize learning in the new...

    Keywords: geneticsImmunologyBiochemistrybioinformaticsmolecular evolutionpublic healthvirusCOVID19

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    Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems
    In evolution classrooms, introducing and reinforcing the idea of genetic drift and random selection can be challenging, as can be reinforcing appropriate mental models of evolution. Agent-based...

    Keywords: modelingEvolutionecologyagent-based modelingGenetic Driftenvironmental scienceNatural Selectioncompetitive coevolutionsimulation modelingevolutionary reasoning

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    How Do Kidneys Make Urine From Blood? Qualitative and Quantitative Approaches to Filtration, Secretion, Reabsorption, and Excretion
    The function of the kidneys is to help maintain a constant internal environment (homeostasis) by regulating the volume and chemical composition of the blood. This regulation occurs via three...

    Keywords: collecting ductexcretionglomerular filtration rate (GFR)nephron tubulereabsorptionrenal corpusclesection

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    From Dirt to Streptomyces DNA
    The purpose of this semester-long Lesson is to give students an authentic, course-based undergraduate research experience during which they learn basic and advanced microbiological and molecular...

    Keywords: MetabolismAntibiotic productionrRNA genesSecondary metabolitesStreptomyces

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    Targeting Misconceptions in the Central Dogma by Examining Viral Infection
    Understanding the central dogma and how changes in gene expression can impact cell function requires integration of several topics in molecular biology. Students often do not make the necessary...

    Keywords: datatranscriptionvirustranslationprotein functionmembrane transportPredictions

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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has...

    Keywords: bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

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