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    Sanger Sequencing by Hand: Using Paper Clips to Demonstrate Chain Termination
    Sanger sequencing is commonly taught with a hands-on approach. Sanger sequencing involves chain termination by dideoxynucleotides, because they are missing the oxygen on the 3’ carbon atom,...

    Keywords: nucleotidessequencingDNAgel electrophoresisChain Termination

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    A Muscular Dystrophy Case Study Illustrating the Phenotypic Effects of Mutation
    Mutations in genes can lead to a variety of phenotypes, including various human diseases. Students often understand that a particular mutation in a single gene causes a disease phenotype, but it is...

    Keywords: mutationProtein Structureethicscentral dogmahuman disease

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    A Quick and Simple Natural Selection Role Play
    Teaching evolution remains a challenging task in biology education. Students enter the classroom with stubborn misconceptions and many traditional examples of the process of evolution may not...

    Keywords: EvolutionfitnessNatural Selectionheritability

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    Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience
    Although genetics is an invaluable part of the undergraduate biology curriculum, it can be intimidating to students as well as instructors: Students must reduce their reliance on memorization and...

    Keywords: geneticsbioinformaticsdrosophilachi-square analysiscomplementation mappingmode of inheritancethree-point mapping

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    Structuring Courses for Equity
    As instructors, we continually look for new ways to create equitable learning environments and support learning for all students in our courses. Recently, we have explored ways that we can increase...

    Keywords: Equitymetacognitioninclusivitycourse structure

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    Visits to the writing center and office hours provide students structured reflection and low-stakes feedback on scientific writing in an Introductory Biology course
    Effective written communication of scientific concepts is a critical, but difficult skill for undergraduate STEM majors to acquire. Oftentimes, the grades of lab reports are negatively impacted by...

    Keywords: scientific writingwater qualityanalysis of results

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    Learning to Pipet Correctly by Pipetting Incorrectly?
    Beginning undergraduate students in biology need basic laboratory, data analysis, and science process skills to pursue more complex questions in course-based undergraduate research experiences...

    Keywords: statisticslaboratorypipetting

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    A Team-Based Approach to Course Development Involving Undergraduate Researchers
    Development of an undergraduate laboratory course can be a challenge, because of the need to balance both logistical and pedagogical considerations. We piloted a team-based approach to developing...

    Keywords: student researchcourse development

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    Sex and gender: What does it mean to be female or male?
    This lesson provides three activities to engage non-science major students in a discussion about sex, gender, gender identity, and sex determination. Students prepare for the lesson by reading a...

    Keywords: gendersex determinationgender identitysex

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    Air Quality Data Mining: Mining the US EPA AirData website for student-led evaluation of air quality issues
    Air pollution directly affects human health endpoints including growth, respiratory processes, cardiovascular health, fertility, pregnancy outcomes, and cancer. Therefore, the distribution of air...

    Keywords: data miningenvironmental justiceair qualityairpollutionspatial reasoning

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    A Strategy for Teaching Undergraduates to Write Effective Scientific Results Sections
    Most undergraduate instructors would agree that learning to write about data in the style of a scientific research paper is a worthy goal for their students.  However, many hesitate to tackle...

    Keywords: data analysisprimary literaturescientific writingcommunicating science

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    Mock Drug Activity Enhances Student Learning About the Challenges of HIV/AIDS Therapy
    While traditional didactic coursework is important for learning about the scientific aspects of HIV/AIDS, it is difficult to convey social aspects of the epidemic. Due to effective drug therapies,...

    Keywords: drug resistanceRetrovirusViral replication

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    Diversifying and Humanizing Scientist Role Models Through Interviews and Constructing Slide Decks on Researchers’ Research and Life Experiences
    To maintain recruitment and retention, biology teachers face the challenge of finding relatable role models for their students. Our ever-increasing scientific knowledge has been facilitated by...

    Keywords: researchdiversityinclusionScientific ProcessRepresentationScientistRole Models

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    A Kinesthetic and Collaborative Activity to Improve Conceptual Understanding of Chemical Equilibrium
    While teaching in large lecture halls, it is challenging even for experienced teachers to hold their students’ attention for the entire class period. Owing to the large enrollment in STEM...

    Keywords: collaborationdemonstrationchemistrykinesthetic learningequilibriumhands-on learning

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    Helping Students to Metacognitively Read Scientific Literature With Talking to the Text
    Reading primary scientific literature enhances students’ understanding of material, increases their self-efficacy, and critical thinking skills. However, scientific articles often present...

    Keywords: scientific literaturereading comprehensionmetacognitionScience process skillsTalking to the TextDense Scientific Texts

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    Why Do I Need a Lab Notebook? Teaching Responsible Conduct of Research with CURE Lab Notebooks
    There are few instructional tools about data acquisition and management available for undergraduate students. I created this lesson as a Fellow of the Ethics Network for Course-Based Opportunities...

    Keywords: lab notebookresponsible conduct of researchdata acquisition/ management

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    Integrating Community Ecology Into the Study of Parasites: Exploring the Effect of Host Behavior on Parasite Transmission Rates
    Organismal life cycles are often presented as a set of facts to memorize in undergraduate biology courses. This approach is cognitively demanding for students and fails to convey how central life...

    Keywords: statisticsspecies interactionsQuantitative reasoninggraphsCommunity EcologyParasitologyfood webs

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    Learning Quantitative Genetics: Investigation of Genetic Control for Cold Stress Response in Plants
    Course-embedded undergraduate research experiences (CUREs) for students have been shown to increase students’ understanding of the process of science, affirm their scientific identity, and...

    Keywords: data analysisrecombinationplantsquantitative geneticsabiotic stress responsegenetic control of complex traitsinheritance of complex traits

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    Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis
    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education,...

    Keywords: transcriptioncentral dogmatranslationsequence analysisDNA replicationgenetic variants

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    How Do Kidneys Make Urine From Blood? Qualitative and Quantitative Approaches to Filtration, Secretion, Reabsorption, and Excretion
    The function of the kidneys is to help maintain a constant internal environment (homeostasis) by regulating the volume and chemical composition of the blood. This regulation occurs via three...

    Keywords: collecting ductexcretionglomerular filtration rate (GFR)nephron tubulereabsorptionrenal corpusclesection

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