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    Using Synthetic Biology and pClone Red for Authentic Research on Promoter Function: Introductory Biology (identifying new promoters)
    Students often memorize the definition of a transcriptional promoter but fail to fully understand the critical role promoters play in gene expression. This laboratory lesson allows students to...

    Keywords: bacteriasynthetic biologygene regulationtranscriptionstudent researchcentral dogmacloningpromoterreporter gene/protein

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    Linking Genotype to Phenotype: The Effect of a Mutation in Gibberellic Acid Production on Plant Germination
    Basic concepts in genetics and plant development are often taught in lecture courses without a lab component. This approach provides students with the content knowledge, but fails to make...

    Keywords: geneticsdevelopmentmutationgerminationplantmodel organismGenotype/PhenotypeHormoneSeed

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    2013-Deboeck-Bergeman-The reservoir model-DE model of psychological regulation
    The following article describes a differential equation model based on the concept of a reservoir for psychological regulation.

    Keywords: adaptive copingReservoirsNotre Dame Longitudinal Study on Agingoutputinput distributionstressorscoping resources

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    Modeling the lac Operon to Understand the Regulation of Gene Expression in Prokaryotes
    This resource is a recitation activity designed for an introductory biology course in which students explore a lac operon simulation (https://qubeshub.org/resources/phetlacoperon).

    Keywords: simulationLac Operon

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    Green Design: How do Leaf Structures Optimize Photosynthesis and Promote Survival?
    One of the major learning objectives established by the American Society of Plant Biologists and the Botanical Society of America has students answer the question: How do plant structures enable...

    Keywords: photosynthesisepidermal layerleaf anatomymesophyllpalisade parenchymaplant anatomyplant structure functionspongy parenchymaStomata

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    2006-Shigui_Ruan-Delay differential equations in single species dynamics
    In this survey, we shall review various delay differential equations models arising from studying single species dynamics.

    Keywords: allee_effectdelayed biological systemsfood limitperiodiciityrecruitment modelRegulation of Haematopoiesis

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    Regulación de expresión génica y adipogénesis por PPAR-γ
    En ésta actividad de dibujo / coloreado los estudiantes aprenderán sobre los diferentes componentes involucrados en la regulación de la activación de PPAR-γ, un factor de transcripción que juega un...

    Keywords: videosResources @ HHMI - BioInteractiveGeneral biology educationgene expressionregulationtranslation into spanishtranscriptional regulationrepressorEspañol

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    Necessary and Sufficient? Solving the Mystery of the Mitochondrial Pyruvate Transporter
    While there are several available lessons for teaching introductory biology students about diffusion, facilitated diffusion, and active transport, fewer materials exist to support upper-division...

    Keywords: DiffusionActive transportfacilitated diffusionNecessary and sufficientTransport proteins

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    Engaging Undergraduates in Mechanisms of Tubular Reabsorption and Secretion in the Mammalian Kidney
    If students fail to see the connections among physiological systems, they can become overwhelmed with the amount of information they need to learn. Some students have particular difficulty with the...

    Keywords: OsmosisActive transportMass flowRenal reabsorptionRenal secretionTransport across membranes

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    Make It Stick: Teaching Gene Targeting with Ribbons and Fasteners
    Manipulating gene expression is a commonly used tool to study the effect of a single gene or the hierarchy of gene networks in many different biological disciplines. When working with mice, the...

    Keywords: mathematical modelhomologous recombinationCre/loxgene targeting

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    2016-Barbarossa-Kuttler-Mathematical Modeling of Bacteria Communication in Continuous Cultures
    This paper presents a simple system of delay differential equations (DDEs) for quorum sensing of Pseudomonas putida with one positive feedback plus one (delayed) negative feedback mechanism.

    Keywords: gene regulatory networkschemostatbifurcationNumerical Simulationquorum sensing

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    Generating Biological Hypotheses in a "Course-based Undergraduate Research Experience"(CURE) Course
    Hypotheses are often incorrectly defined as educated guesses or if/then statements. Further confusion arises from the fact that not all disciplines define hypotheses similarly. The difficulty in...

    Keywords: scientific methodHPT axisNeural stem cells

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    Walkabout: An Easy to Use, Experiential Learning Activity for Applying Abstract Concepts to the Real-World
    Students can have difficulty recognizing examples of course concepts in the real-world. They particularly struggle with phenomena that are ambiguously defined, have mimics, or are hard to...

    Keywords: data gatheringgreen technologyobservations

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    2012-Bech-EtAl-Resources For Engineering Applications Of Math
    Illustrations of applied mathematics including statics, truss, heat equation, column analysis, coupled oscillators, feedback control, AC circuit, chemical reactions, kinetics.

    Keywords: kineticsheat equationcolumn analysiscoupled oscillatorsfeedback controlAC circuitchemical reactions

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    A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience
    A core competency identified in Vision and Change for undergraduate biology students is the Ability to Apply the Process of Science. Here, we describe a three-week laboratory module for students in...

    Keywords: metacognitiongene expressionScientific ProcessExperimenal DesignHypothesis Generationmodel organisms

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    Students require a deep understanding of the central dogma before they can understand complex topics such as evolution and biochemical disorders. However, getting undergraduate biology students to...

    Keywords: Protein Structurecomputational modelingcentral dogmaplant leaf structurePhenotype/Genotype

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    The Lecture-Free Classroom: Teaching students backward design and Bloom's Taxonomy to create their own learning environment
    We describe Presentation Enhanced Learning (PEL), a flexible, lecture-free, field-tested teaching format to promote problem-based, active learning in upper-division or graduate biological sciences...

    Keywords: active learningbackward designProblem based learningBloom's Taxonomy

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    TuNE-BIO - Transforming Assessment, Feedback, and Grading in Undergraduate Biology Education (RCN-Introduction)
    The aim of TUnE-BIO is to transform assessment, feedback, and grading practices in undergraduate biology classrooms to combat “weed-out” culture and decrease inequities. Our incubator year focused...

    Keywords: RCN-UBE Introduction

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    Reflective Writing Tools: Building Skills and Habits of Thinking in Becoming a Scientist
    Reflective writing tools are intended to help students better connect current learning experiences to prior learning, engage the role of emotion in current and future learning, and assess learning...

    Keywords: STEM educationreflective writingMentorshipambiguityindependenceperseverance

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

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