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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric...

    Keywords: pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy

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    1989-R_Blickhan-Spring Mass Model For Running-Hopping
    A simple spring—mass model consisting of a massless spring attached to a point mass describes the interdependency of mechanical parameters characterizing running and hopping of humans as a function...

    Keywords: spring massjumpjumping

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    1967-Israelsson- Johnsson-Circumnutations In Helianthus Annuus
    A theory is given for circumnutations in plants, especially hypocotyls of Helianthus annuus, which were used as experimental material.

    Keywords: plantoscillationdelaycircumnutationturning

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    1-092-DashItAll-ModelingSenario
    This project uses very basic physics, Newton's Second Law of Motion, to model the motion of a sprinter running down a track. We derive the classic Hill-Keller model for a sprinter exerting...

    Keywords: datarunningsprintHill-Kellerworld recordOlympics

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    3-110-MilitarySpringMassApplication-ModelingScenario
    The is a collection of different scenarios for the shock system of a trailer. In each scenario, students will transform the shock system of a trailer into a second-order differential equation,...

    Keywords: dampingresonancebeatsspring-mass systemLaplace TransfomDirac Delta function

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    The Happy Blue Baby Hemoglobin
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    Natural Selection and Galápagos Finches
    A worksheet and accompanying data set that guides students through making and interpreting frequency distributions, selection differentials, and fitness functions.

    Keywords: EvolutionResources @ HHMI - BioInteractive

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    Forests for the Future: How Can Trees Offset Carbon Emissions?
    This activity explores the chemistry and biology underlying forest carbon sequestration, a process that removes carbon from the atmosphere via photosynthesis and storage in plant tissues and soils....

    Keywords: carbon foot printCarbon sequestration of forests vegetationforest ecology (structure and function)

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    2014-XM-Huang-Ordinary Differential Equation Model and its Application in the Prediction Control of Population
    In this paper, we study two kinds of ordinary differential equation models, i.e., Malthus model and Logistic model, and discuss their applications in the prediction control of population.

    Keywords: population dynamicsLogistic modelMalthus ModelPopulation Prediction Control

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    2016-Wilkie-EtAl-Using ODEs to Explore Cancer-Immune Dynamics and Tumor Dormancy
    Here we present a general method using ordinary differential equations (ODEs) to model and analyze cancer-immune interactions, and in particular, immune-induced tumor dormancy.

    Keywords: cancertumor-inhibiting cytotoxic actiontumor-promoting inflammationimmune-induced tumor dormancytumor growth dynamics

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    2012-Lensyl-Urbano-The Draining of a Plastic Bottle-Integrating a Physics Experiment into Calculus
    I punched a small hole (about 1mm radius) in a one gallon plastic bottle and had my students measure the rate at which water drained.

    Keywords: in-class activityexperimentTorricelli's Lawcylinder of waterexpderiment

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    2009-Shamim-EtAl-Investigating viscous damping using a webcam
    We describe an experiment involving a mass oscillating in a viscous fluid and analyze overdamped, critically damped and underdamped regimes of harmonic motion.

    Keywords: laboratoryunderdampedoverdampedcritically dampedharmonic motionimage processingviscous fluid

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    1999-Leonid_Hanin-Which tank empties first
    Suppose that water towers like those shown in the opening are initially filled with water and have the same volume, height, and cross-sectional outlet area. Which one empties first?

    Keywords: tankTorricelli's Lawspherical tankemptyfrustrum of conecylinder

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    7-011-CoupledSystemLaplace-ModelingScenario
    Differential equations and Laplace transforms are an integral part of control problems in engineering systems. We consider a baby warming device.

    Keywords: transfer functionpolycarbonatebaby heatercoupled systemheating

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    7-006-LaplaceTransformBirth-TechniqueNarrative
    We present a way of introducing the Laplace Transform as the continuous analogue of a power series expression of a function.

    Keywords: Transformationspower series

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    1-010-AtmosphericCO2Bifurcation-TechniqueNarrative
    Students are introduced to the concept of a bifurcation in a first-order ordinary differential equation (ODE) through a modeling scenario involving atmospheric carbon dioxide whish is taken as a...

    Keywords: carbon dioxideSurface Atmosphere Exchangebifurcationfold bifurcationsaddle node

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    1-002-IntegratingFactor-TechniqueNarrative
    We develop a strategy to solve first order differential equations by transforming one side of the equation to the derivative of a product of two functions, thereby making it easy to...

    Keywords: Integrating Factor

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    1-051-OneTankSaltModel-ModelingScenario
    A large tank initially contains 60 pounds of salt dissolved into 90 gallons of water. Salt water flows in at a rate of 4 gallons per minute, with a salt density of 2 pounds per gallon....

    Keywords: compartmentsalttankmixingflow

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    1-063-ThreeHoleColumnOfWater-ModelingScenario
    We consider a column of water with three holes or spigots through which water can exit and ask students to model the height of the column of water over time.

    Keywords: fallingcolumn of waterTorricelli's Lawmultiple spigotsspigots

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    1-067-ModelingWithSigmoidCurves-ModelingScenario
    The assignment considers two well-known models of population growth, Verhulst-Pearl and Gompertz models, for which qualitative and quantitative analyses are provided. The graphs of the...

    Keywords: logisticGompertzsigmoidVerhulst-Pearl

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