You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    Serotonin in the Pocket: Non-covalent interactions and neurotransmitter binding
    This lesson introduces beginning biochemistry students to the concept of a biomolecule binding site, such as a neurotransmitter receptor site or an enzyme active site. A simple organic molecule,...

    Keywords: active sitebindingbinding sitehydrogen bondinghydrophobic effectionic interactionsnon-covalent forces

    2856

    views

    340

    downloads

    0

    comments

    0

    adaptations

    A CRISPR/Cas Guide RNA Design In Silico Activity
    CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become...

    Keywords: bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

    3357

    views

    1274

    downloads

    0

    comments

    0

    adaptations

    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and...

    Keywords: bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor

    3651

    views

    405

    downloads

    0

    comments

    0

    adaptations

    2007-Ramsay-Hooker-Campbell-Cao-Parameter estimation for differential equations-a generalized smoothing approach
    We propose a new method for estimating parameters in models that are defined by a system of non-linear differential equations.

    Keywords: estimating equationfunctional data analysisGauss–Newton methodparameter cascadeprofiled estimationdynamic system

    118

    views

    41

    downloads

    0

    comments

    0

    adaptations

    Using Musical Instruments to Model Negative Feedback in the Hypothalamo-Pituitary-Target Gland Axes
    Homeostasis and negative feedback are crucial, yet difficult, concepts for undergraduates, particularly in the context of the hypothalamo-pituitary axes. This interactive activity was designed to...

    Keywords: cell-cell communicationhomeostasisnegative feedback

    1105

    views

    160

    downloads

    0

    comments

    0

    adaptations

    2017-Allali-EtAl-Mathematical Modeling of the Adaptive Immune Responses in the Early Stage of the HBV Infection
    The aim of this paper is to study the early stage of HBV infection and impact delay in the infection process on the adaptive immune response, which includes cytotoxic T-lymphocytes and antibodies.

    Keywords: logisticHBV infectionadaptive immunie responseT-lymphocytes

    126

    views

    62

    downloads

    0

    comments

    0

    adaptations

    2011-Radouane_Yafia-A Study of Differential Equations Modeling Malignant Tumor Cells in Competition with Immune System
    In this paper, we present a competition model of malignant tumor growth that includes the immune system response. The model considers two populations: immune system (effector cells) and population...

    Keywords: Immunologytumorhopf bifrucation

    222

    views

    54

    downloads

    0

    comments

    0

    adaptations

    Learning Quantitative Genetics: Investigation of Genetic Control for Cold Stress Response in Plants
    Course-embedded undergraduate research experiences (CUREs) for students have been shown to increase students’ understanding of the process of science, affirm their scientific identity, and...

    Keywords: data analysisrecombinationplantsquantitative geneticsabiotic stress responsegenetic control of complex traitsinheritance of complex traits

    2181

    views

    295

    downloads

    0

    comments

    0

    adaptations

    The Science Behind the ACTN3 Polymorphism
    A common polymorphism in the alpha-actinin-3 (ACTN3) gene results in the lack of ACTN3 protein expression in fast twitch muscle fibers in ~16% of the human population (1). This genetic change has...

    Keywords: protein structure and functionhuman genetic variationskeletal muscle physiology

    1376

    views

    192

    downloads

    0

    comments

    0

    adaptations

    Cells of the Immune System
    This tutorial provides an overview of the immune system, concentrating on the roles played by B and T lymphocytes, and on the antigen-presentation system.
    1353

    views

    206

    downloads

    0

    comments

    0

    adaptations

    Figure of the Week: Environmental Data Analysis/Statistics Version
    Adaptation of Figure of the Day activity used on a weekly basis in an environmental data analysis/statistics course.

    Keywords: graphsmath attitudesResources @ BIOMAAPInterpreting Graphs

    1250

    views

    303

    downloads

    0

    comments

    0

    adaptations

    Changes in Lake Ice: Ecosystem Response to Global Change
    This is an FMN participant modification of the TIEE module "Changes in Lake Ice: Ecosystem Responses to Global Change," authored by Robert Bohanan, Marianne Krasny, and Adam Welman in 2005.

    Keywords: ecologyfmnData Discovery

    1873

    views

    276

    downloads

    0

    comments

    0

    adaptations

    1-054-GrowthInFarmland-ModelingScenario
    An enriching project developing a model from data with missing temporal information is described. Students fit functions to the data that leads to the creation of a differential equations model,...

    Keywords: fittingfarmfarmland

    243

    views

    215

    downloads

    0

    comments

    0

    adaptations

    Ciliate Genomics Consortium: a professional learning community sharing modular curricula to support undergraduate research in the classroom
    The Ciliate Genomics Consortium (CGC) employs an integrative teaching and research model that combines both inquiry-driven class laboratory activities and collaborative consortium pedagogies to...
    1912

    views

    413

    downloads

    4

    comments

    0

    adaptations

    Louse Genetics, Genomics, and Gene Function...Oh My!
    In this module, students will be investigating a louse gene with an unknown function to determine if it might be important in the evolution of the louse ecomorphs.

    Keywords: parasitesgenomicsgene sequence analysisFunctional Genomics

    1612

    views

    669

    downloads

    0

    comments

    0

    adaptations

    Splicing it Together: Using Primary Data to Explore RNA Splicing and Gene Expression in Large-Lecture Introductory Biology
    At the heart of scientific ways of knowing is the systematic collection and analysis of data, which is then used to propose an explanation of how the world works. In this two-day module, students...

    Keywords: gene regulationtranscriptiongene expressioncentral dogmarepressoralternative splicingmRNA processingActivatorTranscription factors

    3957

    views

    522

    downloads

    0

    comments

    0

    adaptations

    Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy
    Analyzing high-throughput DNA sequence data is a fundamental skill in modern biology. However, real and perceived barriers such as massive file sizes, substantial computational requirements, and...

    Keywords: bioinformaticsDNA sequenceRNAseqgene expression

    4865

    views

    890

    downloads

    0

    comments

    0

    adaptations

    Engaging Undergraduates in Mechanisms of Tubular Reabsorption and Secretion in the Mammalian Kidney
    If students fail to see the connections among physiological systems, they can become overwhelmed with the amount of information they need to learn. Some students have particular difficulty with the...

    Keywords: OsmosisActive transportMass flowRenal reabsorptionRenal secretionTransport across membranes

    1926

    views

    363

    downloads

    0

    comments

    0

    adaptations

    Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab
    In response to the growth of biology datasets and broad efforts to digitize data, an increasingly important skill for science students is the management and analysis of large datasets. We designed...

    Keywords: data analysisnatural historyphylogenyBiodiversitymammalsAllen's RuleBergmann's Ruleecogeographymuseum research

    2672

    views

    684

    downloads

    0

    comments

    0

    adaptations

    2005-JC_Sprott-Dynamical Models of Happiness
    A sequence of models for the time evolution of one’s happiness in response to external events is described.

    Keywords: happinessoscillation

    209

    views

    93

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search