You are here: Home / Resources / Browse Resources

Open. Adaptable. Free.

Resources created by our members and partners.

The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

Text Search:
Applied Filters
    Sickle Cell Anemia using Nicholas’ Story
    The goal of this exercise is to introduce students to 3-D structures of biological molecules, visualize and manipulate them to understand their functions. The exercise also helps them see the...

    Keywords: Hemoglobinsickle cell diseaseMolecular Case Study

    1140

    views

    637

    downloads

    0

    comments

    0

    adaptations

    Mentoring Undergraduate Research Projects in Mathematical Biology
    Part of the 2015 SMB Minisymposium: Topics in Biomathematics Education

    Keywords: epidemiologymentoringcurriculumundergraduate researchGene regulatory networkpest management

    1453

    views

    218

    downloads

    0

    comments

    0

    adaptations

    GSEAtheory
    Brief introduction to how gene set enrichment analysis works.

    Keywords: videosbioinformaticsgenomicsyoutubegsea

    1358

    views

    258

    downloads

    0

    comments

    0

    adaptations

    Bioinformatics: the Power of Computers in Biology – a Practical Guide
    This Practical Guide in the Bringing Bioinformatics into the Classroom series introduces simple bioinformatics approaches for database searching and sequence analysis.

    Keywords: NIBLSEGOBLET

    1066

    views

    273

    downloads

    0

    comments

    0

    adaptations

    Module 2: Transcription Part I: From DNA Sequence to Transcription Unit
    This module illustrates how a primary transcript (pre-mRNA) is synthesized using a DNA molecule as the template. Students will learn about the importance of the 5' and 3' regions of the gene for...

    Keywords: data visualizationmolecular biologybioinformaticsGenome BrowsergenomicsTranscription InitiationTranscription Start SiteTranscription Termination Signal

    1698

    views

    3288

    downloads

    0

    comments

    0

    adaptations

    RNA-seq Analysis
    In this computer lab module, students learn how to process an RNA-seq data set to identify differentially expressed genes (DEGs). The samples for this data set were collected from yeast cells...

    Keywords: LabRNAsequencingUndergraduateNIBLSEincubatorsRNAseqInstructional SettingAudience LevelActivity LengthMore than 1 hourC4. Bioinformatics toolsC5. Data retrievalReviewed at NIBLSEdifferentially expressed genes

    1688

    views

    298

    downloads

    0

    comments

    0

    adaptations

    Using Raw Sequence Data to Analyze Tumor Suppressor Mutations
    Learning to identify DNA sequence variants from raw sequencing data (electropherograms) is a basic molecular biology skill with applications to basic research and clinical practice. Yet learning to...

    Keywords: bioinformaticsmutationDNAgenomic visualizationparts of a geneclinical consequencesraw data

    403

    views

    53

    downloads

    0

    comments

    0

    adaptations

    Make It Stick: Teaching Gene Targeting with Ribbons and Fasteners
    Manipulating gene expression is a commonly used tool to study the effect of a single gene or the hierarchy of gene networks in many different biological disciplines. When working with mice, the...

    Keywords: mathematical modelhomologous recombinationCre/loxgene targeting

    1550

    views

    227

    downloads

    0

    comments

    0

    adaptations

    DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.
    Advances in high-throughput techniques have resulted in a rising demand for scientists with basic bioinformatics skills as well as workshops and curricula that teach students bioinformatics...

    Keywords: geneticsbioinformaticsDNAgenotypephenotypegenegene annotation

    2093

    views

    343

    downloads

    0

    comments

    0

    adaptations

    Gene Expression in Stem Cells
    The module served as in introduction to the Gene Expression unit. It was implemented in two phases, a pre-class activity and an in-class activity to introduce chapter concepts and reinforce...

    Keywords: small group activitypre-class activityGeneral Biology

    3124

    views

    718

    downloads

    0

    comments

    0

    adaptations

    Build Multiomic and Visualization Skills in Bioscience Lecture
    This resource promotes inclusive learning by using all free platforms to extend the central dogma to an applied experience. Genomics is focused on with literature reviews that are performed to...

    Keywords: geneticsBiochemistryBiology and Biochemistry EduationProtein StructureBioinformatics and GenomicsFunctional GenomicstranscriptomicsproteomicsRNAseqClinical genomicsprotein structure modelingInclusive teaching3D protein structure /function analysisinclusive classrooms3D protein structuresinclusivegene

    1139

    views

    251

    downloads

    0

    comments

    0

    adaptations

    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

    2551

    views

    786

    downloads

    0

    comments

    0

    adaptations

    Using genome browsers constructed by G-OnRamp to provide students with a Course-based Undergraduate Research Experience in genome annotation
    G-OnRamp (http://g-onramp.org) provides an easy-to-use web platform for educators to create genome browsers to engage undergraduate students in research projects, both collaborative annotation of...
    674

    views

    202

    downloads

    0

    comments

    0

    adaptations

    BLAST-HGT PROJECT
    Genome Solver modules were combined to make one project for students using tools within NCBI BLAST to explore phylogenetics and horizontal gene transfer from phage to Chlamydia.
    1165

    views

    921

    downloads

    0

    comments

    0

    adaptations

    Differential Gene Expression during Xenopus laevis Development
    In Developmental Biology classes, students are challenged with understanding how differential gene expression guides embryonic development. It can be difficult for students to realize that genes...

    Keywords: gene expressionXenopusearly developmentembryofertilizationin situ hybridization

    1572

    views

    306

    downloads

    0

    comments

    0

    adaptations

    Linkage Analysis
    This Excel workbook simulates a linkage analysis problem with up to four alleles. Based on the offspring produced by a multihybrid testcross, the user builds a model of the gene order,...

    Keywords: recombinationlinkage analysis

    67

    views

    21

    downloads

    0

    comments

    0

    adaptations

    DeFinetti 1.0
    This Excel workbook simulates evolution of a single gene with three alleles. The user assigns fitness values to each of the six possible genotypes, then enters starting allele frequencies for each...

    Keywords: population geneticsallelesevolutionary fitness

    63

    views

    33

    downloads

    0

    comments

    0

    adaptations

    The Human Microbiome Biodiversity in Health and Disease
    The students will analyze the human gut and vaginal microbiomes in healthy and diseased states using diversity of bacteria as determined by 16SrRNA sequence.
    1092

    views

    736

    downloads

    0

    comments

    0

    adaptations

    Using Bioinformatics to Understand Genetic Diseases: A Practical Guide
    This Practical Guide outlines a number of basic bioinformatics approaches that can be used to understand the molecular basis of genetic diseases.
    905

    views

    189

    downloads

    0

    comments

    0

    adaptations

    Student and Faculty Tools for Generating High-Quality Phage Annotations
    Phage genome annotation requires collaboration between faculty and their student research team. This set of resources provides tools to assist both students and faculty in the evaluation and...
    1096

    views

    1223

    downloads

    0

    comments

    0

    adaptations

    Close

    Home

    Search