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    Bioimage Informatics Activity
    Students use basic bioimage informatics techniques to acquire quantitative data from images of cultured cells and test a hypothesis about the effect of a genetic mutation on cellular phenotypes

    Keywords: geneticsResources @ HHMI - BioInteractivegenomicscancergenetic basis of diseasebiology of cells

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    A BioGraphy of Life: How Graph Theory Makes Mathematics Recognizable, Relevant, and Research-Rich in Biology Education
    Presentation given at the 2106 SIAM Conference on Applied Mathematics Education on graph theory.

    Keywords: graph theory

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    Sickle Cell Disease Case Study
    A short film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia. The animation explores the genetic causes and biological...

    Keywords: HHMI BioInteractive

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    Processes that Regulate Patterns of Species and Genetic Diversity
    This activity was developed for an undergraduate upper level ecology course for Environmental or Biological Science majors. Classes of ~20 students work best for the activity.
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    DCS 105 Calling Bull F24 Schedule
    Schedule overview for Bates College Course DCS 105 Calling Bull

    Keywords: datacalling bullmisinformationBates CollegeSchedule

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    Osmosis: Determination of the rate of osmosis and the isotonic concentration
    This module contains exercises designed to help students understand how solute concentrations affect the direction and rate of osmosis. Students are given different scenarios to predict the...

    Keywords: introductory biologyQuantitative reasoninginterdisciplinarycell functionOsmosisNIQBC2. Data and GraphsC4. mathematical modelsC6. Quantitative LanguageC1. NumeracyC5. Logic and Algorithms

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    2009-Su-EtAl-Fitting Compartmental Models to Multiple Dose Pharmacokinetic Data using SAS
    In the case of a multiple dose study where subjects experience different dosing times, a superposition principle can be used to recursively account for each additional dose.

    Keywords: SASsuperpositionpharmacokineticscompartmental modelsmultiple dose

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    Bioinformatics: Investigating Sequence Similarity - A Plant Biology Approach
    This laboratory module is a modification of the original published on CourseSource with a focus on plant biology. In the final activity, students conduct a BLAST to compare histone protein...

    Keywords: phylogeneticsbioinformaticssequencingFASTANCBIplant biologyNIBLSEalgorithmsincubatorsPlant and Fungal EvolutionBLASTmultiple sequence alignmentsequence similarityBLOSUM scoring matrixneighbor-joining distance matrixCourseSourcephylogram

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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently...

    Keywords: modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology

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    Teaching the Central Dogma Using a Case Study of Genetic Variation in Cystic Fibrosis
    The central dogma of biology is a foundational concept that is traditionally included in genetics curricula at all academic levels. Despite its ubiquitous presence throughout genetics education,...

    Keywords: transcriptioncentral dogmatranslationsequence analysisDNA replicationgenetic variants

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    Venom Diversity & Evolution in Reptiles and Amphibians - An education module for university students
    This module contains information for a three part series introducing the venom system in reptiles and discussing it in an evolutionary context. In the first part venom and its ecological roles are...

    Keywords: geneticsEvolutionecologyHerpetologyAmphibans and ReptilesVenom

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    Happy Blue Baby
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved on its own...

    Keywords: mutationHemoglobinmolecular visualization and analysisgenetic basisPDBMolecular Case StudyMol*

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    The Happy Blue Baby Hemoglobin
    This case, about a specific mutant of hemoglobin, focuses on visualizing and understanding the molecular basis of why an infant turned blue soon after birth and how the cyanosis resolved.

    Keywords: mutationHemoglobinmolecular visualization and analysisPDBMolecular Case Study

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    Teaching Genetic Linkage and Recombination through Mapping with Molecular Markers
    Most introductory genetics courses cover genetic linkage, a core concept in the CourseSource genetics learning outcome framework. Although it is a classical genetics topic, genetic linkage remains...

    Keywords: meiosisphenotypegel electrophoresismicrosatellitesBanding PatternGenetic linkageInheritanceMolecular MarkersPhysical Linkage

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    Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems
    In evolution classrooms, introducing and reinforcing the idea of genetic drift and random selection can be challenging, as can be reinforcing appropriate mental models of evolution. Agent-based...

    Keywords: modelingEvolutionecologyagent-based modelingGenetic Driftenvironmental scienceNatural Selectioncompetitive coevolutionsimulation modelingevolutionary reasoning

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    2008-Chernyshov-EtAl-The Problem of Modelling of Economic Dynamics in Differential Form
    The authors have tried to analyze procedures of the construction of differential equations that are employed for modeling of macroeconomic processes. The results prove to be rather unexpected.

    Keywords: Fredholm integral equation ofLeontief’s modelmacroeconomic processes

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    DeFinetti 1.0
    This Excel workbook simulates evolution of a single gene with three alleles. The user assigns fitness values to each of the six possible genotypes, then enters starting allele frequencies for each...

    Keywords: population geneticsallelesevolutionary fitness

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    Navigating Bacterial Changes in Aging Organisms: Graphs, Patterns, and Models
    Aging is an incredibly important area of research, and recent biological advances implicate the intestines in aging pathologies. Given that the gut harbors an immense amount of an organism’s...

    Keywords: statisticsgraphingmathematics for life sciencesmathexponential growthPrecalculus

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    Casting a Wide Net via Case Studies: Educating across the undergraduate to medical school continuum in the biological sciences
    This article seeks to help bridge undergraduate and medical educators by describing shared educational goals and strategies, highlighting resources relevant for both groups, and exemplifying shared...

    Keywords: genetic testingdirect-to-consumer genetic testinginformed consentprenatal screeningsecondary findingswhole genome sequencing

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    Exploring Fitness and Population Change under Selection: Avida-Ed Lab Book Exercise 3
    An introductory activity exploring the process of natural selection in action using the Avida-ED simulation.

    Keywords: population geneticsfitnessavida-edsoftware simulationsSelectionevolutionary fitness

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