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    The Science Behind the ACTN3 Polymorphism
    A common polymorphism in the alpha-actinin-3 (ACTN3) gene results in the lack of ACTN3 protein expression in fast twitch muscle fibers in ~16% of the human population (1). This genetic change has...

    Keywords: protein structure and functionhuman genetic variationskeletal muscle physiology

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    My Dog IS My Homework: Exploring Canine Genetics to Understand Genotype-Phenotype Relationships
    To facilitate understanding of the fundamental genetic concept of the genotype-phenotype relationship in our introductory biology students, we designed an engaging multi-week series of related...

    Keywords: gel electrophoresissequence analysiscanine geneticsdeoxyribonucleic acid (DNA)dog coat morphologygenotype and phenotypemutationsPolymerase chain reaction (PCR)single nucleotide polymorphism (SNP)

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    Cutthroat trout in Colorado: A case study connecting evolution and conservation
    Evaluation of evidence is a key process skill for the core competencies of applying the process of science and using quantitative reasoning. This case study enables upper-division biology students...

    Keywords: population geneticsphylogeneticsSpeciationdivergencegene flow

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    Role of Crop Genetic Diversity on Pathogen Impact: The Tale of Two Pathogens
    Introductory genetics courses are part of the core curriculum in many different fields, including plant breeding, animal science, biology, microbiology, and natural resource management. Concepts...

    Keywords: plant pathologygenetic diversityDisease TriangleModes of Reproduction

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    The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics
    Coursework connecting biology to socially relevant issues and ethical questions can help students think about biology in interdisciplinary terms. Gene drives represent one topic involving both...

    Keywords: bioethicsCRISPR/Cas9Genetic modificationGene drives

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    Student-Generated Analogies for Learning about Information Flow
    Using analogies is a standard practice for both teaching and communicating ideas in science. Here we upend the traditional lesson, where the instructor provides a fully constructed analogy and...

    Keywords: critical thinkingcentral dogmaanalogical reasoning

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    SCIENCE/Fiction: Modular Template for Class Design
    We present a modular scaffold for designing an introductory seminar using speculative fiction and science papers to welcome university undergraduates to the biology major. A list of twelve possible...

    Keywords: geneticscell biologyneurosciencesystems biologyScience Fiction

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    Integrating Manipulatives and Animations to Visualize Holliday Junctions
    The complex molecular architecture of Holliday junctions is often challenging for undergraduate biochemistry students to conceptualize. In particular, they have difficulty translating from...

    Keywords: dna structureDNA damageDNA recombinationGene crossoverHolliday junction

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    From Cre/LoxP to Fate Maps: Inclusive and Equitable Approaches for Engaging Developmental Biology Students in Experimental Design
    Engaging first generation underrepresented minority students in the process of inquiry in developmental biology is important to increase diversity in future graduate STEM education. One important...

    Keywords: experimental designC. elegansCre/LoxPFate mapheart developmentheart regenerationmousereporter constructzebrafish

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    A Case Study for Teaching Toxicology: Using Whales as an Indicator for Environmental Health
    One of the challenges of teaching scientific courses is helping students understand research methods, biological models, and data analysis, which can be especially difficult in classes without a...

    Keywords: absorptionone environmental health hypothesismetals

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    Writing Microbiology Resource Announcements (MRA)
    This resources provides a framework for students to write a Microbiology Resource Announcement, collaboratively.

    Keywords: phageBioinformatics and GenomicsGenome announcementmanuscriptMRA

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    STEM Inclusive Teaching Practices Webinar Series: The Biocultural Labels Initiative
    The Biocultural (BC) Labels initiative is focused on accurate provenance, transparency and integrity in research engagements with Indigenous communities. ...

    Keywords: dataEquitynatural history museumsAttributionBiocultural LabelsTraditional Knowledge LabelsIndigenous data sovereigntyIndigenous rights

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    Responses to Climate Change in California Chipmunks: Move, Adapt, or Die
    A series of three modules using data from natural history museum collections to examine responses to climate change in multiple chipmunk species. Elevation and morphological data, beginner skills...

    Keywords: statisticsmodelingmodulemorphologysummary statisticsmodulesclimate datamuseumsclimate changeundergraduate educationR programming languageprogrammingelevationnatural history museumsmammalssmall mammals community dynamicsmuseum collectionsVertebrate Morphologyopen educational resourceR programming environment

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    Avida-ED Lab Book
    Avida-ED activities, modified for the Argentina 2019 Avida-ED Workshop, presented at the 2019 BioQUEST & QUBES Summer Workshop

    Keywords: Evolutionavida-ed

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    Ripped from the Headlines! Creating Case Studies from Primary Literature.
    Poster on using case studies developed from primary literature presented at the 2018 QUBES/BioQUEST Summer Workshop

    Keywords: case studyprimary literatureSummer Workshop 2018

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    Geoscience Methods and Resources for K-5 Pre-Education Majors
    : Exploring Geoscience Methods was an excellent capstone experience for Elementary Education Majors. The class I used this module with was 24 students of various backgrounds and academic...

    Keywords: geneticsvideosQUBESecologyResources @ HHMI - BioInteractiveMathematical Biologycalculusjavaorganismal biologyquantitative biologybioinformaticsneurosciencegenomicscancerSecondaryyoutubemicrobiomeFaculty Mentoring NetworksalamanderCapture mark-recaptureAudience level - Introductory UG - majorsAudience level - Introductory UG - non-majorsecosystemsgenetic basis of diseasebiology of cellshuman reproductionfood chainIntroduction to Modelingrandom number generatorPost-secondaryLower DivisionPossible TasksModeling ProjectBuildCompareEvaluateexponential decayrecursionabsorptionelimination

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    Sleep and Learning Lab
    Students use sleep and exam data from Introductory Biology students to investigate the question: Does a circadian rhythm, the sleep-wake cycle, influence an important mammalian adaptation, the...

    Keywords: animal behaviorlab activitycircadian biologysmall group workthink-pair-shares

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    Make It Stick: Teaching Gene Targeting with Ribbons and Fasteners
    Manipulating gene expression is a commonly used tool to study the effect of a single gene or the hierarchy of gene networks in many different biological disciplines. When working with mice, the...

    Keywords: mathematical modelhomologous recombinationCre/loxgene targeting

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    Fly Exercise: A Simple Experiment to Test the Physiological Effects of Exercise on a Model Organism
    Model organisms are commonly used to study and experimentally explore biological processes in ways that are technically or ethically not possible in humans. For this reason, model organisms are an...

    Keywords: exerciseenzyme kineticsmetabolite concentrationmodel speciesphysical activity

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    A Rapid Genetic Screen Using Wisconsin Fast Plants®: A Hands-On Approach to Inheritance of de novo Mutations
    Some concepts in genetics, such as genetic screens, are complex for students to visualize in a classroom and can be cumbersome to undertake in the laboratory. Typically, very large populations are...

    Keywords: mutationInheritancegermlinesomaplant lifecycle

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